High-quality development of manufacturing industry is the main part of realizing high-quality economic development. Taking Shaanxi Province as the research object, 13 evaluation indexes are selected from five aspects: economic benefit, innovation ability, green development, opening to the outside world, social security and support, the provincial panel data from 2010 to 2020 is obtained, each index is weighted by entropy method, then its high-quality development level is evaluated from five aspects, the comprehensive score of high-quality development level of manufacturing industry in each year is obtained , the overall development status of manufacturing industry in Shaanxi Province in recent years and the development status of all levels are analyzed. Some corresponding countermeasures and suggestions is put forward.