The thesis used NREC to design the hydraulic characteristics of the centrifugal blood pump. The design flow rate was 5 L/min and the design speed was 5 000 rpm. Get the three-dimensional structure design plan of the centrifugal impeller and volute. Based on the whole grid, the thesis conducted a simulation study on the three-dimensional steady flow field under the design conditions. Through analysis of hemolysis index , it was found that the shear stress in the 95% area of the centrifugal blood pump is less than 150 Pa, and the maximum shear stress is less than 500 Pa, which meets the human body's requirements for hemolysis of the blood pump. Then building a test platform for the flow-pressure rise characteristic test of a centrifugal blood pump , the xanthan gum solution with a mass fraction of 0.06% was used as a flowing medium. The test results showed that the actual volume flow at the design speed was larger than the design flow. And the overall pressure rise is around 6 550 Pa.