The article used meta-analysis method to carry out a re-analysis with 56 independent empirical research samples about the relationship between interpersonal trust and creativity. The conclusion shows that interpersonal trust can motivate employees’ creativity effectively,and there is a mid-level significantly positive relationship (r=0.34) between interpersonal trust and employees’ creativity. Felt trusted by leaders and Mutual trust between colleagues has more powerful impact on individual creativity than trust in leaders; when data come from the same individual,the impacting strength of the relationship will be higher. The impact of interpersonal trust in employee creativity is significantly greater in the new generation employee group than in the older employee group. The correlation level between interpersonal trust and employees’ creativity is stronger in organizations under eastern cultural background than that of western cultural background,so do the organizations in low development level nations compared with organizations in high development level nations.