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Three‐period,two‐treatment crossover design under long‐term carryover effect
Authors:Suryasish Chatterjee  Uttam Bandyopadhyay
Affiliation:1. Department of Statistics, Bidhannagar College, Kolkata, India;2. Department of Statistics, University of Calcutta, Kolkata, India
Abstract:The paper describes non‐parametric approach for analysis of a three‐period, two‐treatment, four‐sequence crossover design in which test procedure for interchangeability of the treatment effects is obtained. The proposed procedure is based on a non‐parametric model, which incorporates, along with the direct treatment effects and the usual carryover effects, the long‐term carryover effects. Relevant competitors are obtained. Related asymptotic results are given. By performing simulation study, we compared the procedures with respect to type I error rate and power. Furthermore, confidence intervals for treatment differences are studied. The procedures are illustrated with a data study.
Keywords:asymptotic distribution  asymptotic power  asymptotic relative efficiency  asymptotically distribution free  carryover effect  crossover design  exactly distribution free  parallel group design  AMS classification: primary 62G10: secondary 62L05
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