Literature-related discovery (LRD): Lessons learned, and future research directions

Literature-related discovery (LRD) is the linking of two or more literature concepts that have heretofore not been linked (i.e., disjoint), in order to produce novel, interesting, plausible, and intelligible knowledge (i.e., potential discovery). The open discovery systems (ODS) component of LRD starts with a problem to be solved, and generates solutions to that problem through potential discovery. We have been using ODS LRD to identify potential treatments or preventative actions for challenging medical problems, among myriad other applications. The five immediately preceding papers in this Special Issue describe the application of ODS LRD to Raynaud's Phenomenon (RP), cataracts, Parkinson's Disease (PD), Multiple Sclerosis (MS), and Water Purification (WP). We describe the lessons learned from each application, and how the techniques can be improved further.Generation of much potential discovery using ODS LRD is possible when the conceptual roadblocks to discovery are removed. Some of these roadblocks include use of numerical filters that are unrelated to generating discovery, and excessive reliance on literatures directly related to the problem literature of interest. The issue of how to handle large amounts of potential discovery has not been addressed in the literature, since most ODS LRD researchers have tried to find a relatively few potential discovery items. We present a development strategy that capitalizes on the large amounts of potential discovery we have identified.     

亚洲直面通胀挑战

近日，各中央银行纷纷上调利率，或采取其它措施抑制物价上涨，启动新一轮的货币紧缩。尤其是印度，该国家已采取前所未有的强硬措施并大幅上调利率，而中国等其它国家也再度提高准备金要求。亚洲终于觉醒，开始直面通胀挑战。     

Asia Confronts Its Inflation Challenge

Asia is finally waking up to its inflation challenge.Recent weeks have seen a further round of monetary tighten-ing, with a succession of central banks raising interest rates, or taking other measures to put a cap on rising prices.India, in particular, has taken tougher action than before, with a large rate hike, whilst others such as China have again pushed up reserve requirements.     

香港交易所致力推动可持续发展新动向

香港交易所《环境、社会及管治报告指引》的公共意见征求工作将在四月初结束,之后交易所准备进入指引制定的下一阶段,在致力推动亚洲的可持续发展方面迈出实质性的一步。在全球金融市场中,香港交易所已经成为IPO的重要中心,所以此次加强信息披露的要求很重要。通过该指引,香港交易所开始驶上国际轨道,与其他交易所及机构型投资者一样注重企业在环保及社会方面披露信息的重要性,要求     

MUTUAL FUND MORTALITY, 12B‐1 FEES,AND THE NET EXPENSE RATIO

The Securities and Exchange Commission is currently reviewing Rule 12b‐1, which governs how fund advisors may pay for the distribution of fund shares. We provide evidence that even after adjusting for economies of scale, funds with 12b‐1 fees have higher expense ratios net of the 12b‐1 fees than do funds without such fees. This finding suggests that 12b‐1 fees are more than just a deadweight cost. We also demonstrate that 12b‐1 fees are highest for funds that ultimately fail, that the proportion of funds with 12b‐1 fees is increasing over time, and that the level of those fees is also increasing over time.     

展望“里约＋20峰会”把握企业可持续发展趋势

1992年，联合国在巴西里约热内卢举办了联合国环境和发展大会，有183个国家的代表出席。当时各国已感受到生态破坏的威胁，推动了一系列的国际条约以及新的承诺，并正式提出了可持续发展的理念。时隔20年，“联合国可持续发展大会”将于今年6月在巴西里约热内卢举行，因此也被称为“里约＋20峰会”。     

F. L. McDougall: Éminence grise of Australian Economic Diplomacy

This paper examines the principal economic ideas of F. L. McDougall, a largely forgotten, sometime government official and 'amateur' economist who exercised an enigmatic influence upon Australia's economic diplomacy in the interwar years. Beginning with his conception of 'sheltered markets', the international manifestation of the Bruce Government's vision for Australia of 'men, money, and markets', the paper explores McDougall's later advocacy of a 'nutrition approach' to world agriculture and its extension into 'economic appeasement'. McDougall's ideas were theoretically unsophisticated, and realized little in the way of immediate achievements. In the longer run they could be viewed more favourably. Naive perhaps and idealistic certainly, McDougall's ideas were part of a broader movement that, after the Second World War, redefined the role of international economic institutions. If nothing else, McDougall's active proselytizing of his ideas lent Australia an unusual 'voice' in international forums at a time when it was scarcely heard.     

Corporate Ethical Values and Altruism: The Mediating Role of Career Satisfaction

This study explores the ability of career satisfaction to mediate the relationship between corporate ethical values and altruism. Using a sample of individuals employed in a four-campus, regional health science center, it was determined that individual career satisfaction fully mediated the positive relationship between perceptions of corporate ethical values and self-reported altruism. The findings imply that companies dedicating attention to positive corporate ethical values can enhance employee attitudes and altruistic behaviors, especially when individuals experience a high degree of career satisfaction.