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1.
硅酸铁锂是一种锂离子电子的正极材料,由于其晶胞在理论上可允许可逆脱嵌两个锂原子,使得其理论比容量有巨大的提升空间,加上原料易得、无污染及成本低的优势,受到了人们的重视。正极材料掺杂被认为是改善其导电性能的有效途径。论文通过运用基于第一性原理方法的计算机仿真技术,对铬掺杂硅酸铁锂的结构和导电性能的影响进行了计算机仿真研究,结果表明未掺杂的硅酸铁锂其带隙快读为2.44eV,掺杂铬之后硅酸铁锂带隙减小为2.31eV,表明铬掺杂可提高硅酸铁锂的导电性能。  相似文献   
2.
目的:探讨帕罗西汀治疗强迫症患者的临床疗效。方法选取2011年8月至2013年8月收治的符合中国精神障碍分类与诊断标准第3版(CCMD-3)强迫症诊断标准患者100例,按随机数字表法将其分为A组和B两组,各50例。A组患者常规应用帕罗西汀治疗,B组患者应用盐酸氯米帕明治疗。比较两组患者的临床疗效。结果两组患者治疗8周的Yale-Brow强迫量表评分均明显低于治疗前、治疗后4周,呈时间依赖性,差异均有统计学意义(均P<0.05);A组患者的总有效率为96.0%,明显高于B组的80.0%,差异有统计学意义(P<0.05);A组患者的不良反应发生率为10.0%,明显低于B组的28.0%,差异有统计学意义(P<0.05)。结论临床对强迫症患者采用帕罗西汀治疗,效果明显,不良反应发生率低,同时还具有用药方便、剂量小等特点。  相似文献   
3.
《Finance Research Letters》2014,11(4):362-368
Using the Chinese stock market data from 1997 to 2013, this paper examines the “Sell in May and Go Away” puzzle first identified by Bouman and Jacobsen (2002). We find strong existence of the Sell in May effect, robust to different regression assumptions, industries, and after controlling for the January or February effect. However, part of the puzzle is subsumed by the seasonal affective disorder effect. We then construct a trading strategy based on this puzzle, and find that it outperforms the buy-and-hold strategy and could resist the market downside risk during large recession periods.  相似文献   
4.
Abstract

Aims: The current study examined the association between insufficient major depressive disorder (MDD) care and healthcare resource use (HCRU) and costs among patients with prior myocardial infarction (MI) or stroke.

Methods: This was a retrospective study conducted using the MarketScan Claims Database (2010–2015). The date of the first MI/stroke diagnosis was defined as the cardiovascular disease (CVD) index date and the first date of a subsequent MDD diagnosis was the index MDD date. Adequacy of MDD care was assessed during the 90 days following the index MDD date (profiling period) using 2 measures: dosage adequacy (average fluoxetine equivalent dose of ≥20?mg/day for nonelderly and ≥10?mg/day for elderly patients) and duration adequacy (measured as the proportion of days covered of 80% or higher for all MDD drugs). Study outcomes included all-cause and CVD-related HCRU and costs which were determined from the end of the profiling period until the end of study follow-up. Propensity-score adjusted generalized linear models (GLMs) were used to compare patients receiving adequate versus inadequate MDD care in terms of study outcomes.

Results: Of 1,568 CVD patients who were treated for MDD, 937 (59.8%) were categorized as receiving inadequate MDD care. Results from the GLMs suggested that patients receiving inadequate MDD care had 14% more all-cause hospitalizations, 4% more all-cause outpatient visits, 17% more CVD-related outpatient visits, 13% more CVD-related emergency room (ER) visits, higher per patient per year CVD-related hospitalization costs ($21,485 vs. $17,756), higher all-cause outpatient costs ($2,820 vs. $2,055), and higher CVD-related outpatient costs ($520 vs. $434) compared to patients receiving adequate MDD care.

Limitations: Clinical information such as depression severity and frailty, which are potential predictors of adverse CVD outcomes, could not be ascertained using administrative claims data.

Conclusions: Among post-MI and post-stroke patients, inadequate MDD care was associated with a significantly higher economic burden.  相似文献   
5.
目的探讨逍遥丸对人类免疫缺陷病毒(HIV)感染患者抗病毒治疗初期情绪障碍的疗效。方法选取2019年2月至2019年9月于沈阳市第六人民医院AIDS门诊进行治疗的HIV阳性患者300例作为研究对象,采用随机数字表法将其分为对照组和观察组,每组150例。对照组仅进行抗病毒治疗和对症处置,观察组加用逍遥丸,治疗1个月,观察3个月,比较两组治疗前后汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评分变化及CD4^+T淋巴细胞计数变化、不良反应发生情况。结果治疗后,观察组HAMA及HAMD评分优于对照组,CD4^+T淋巴细胞计数升高幅度大于对照组,失眠、腹泻发生率低于对照组,差异有统计学意义(P<0.05)。结论逍遥丸可以改善HIV感染患者抗病毒治疗初期的焦虑及抑郁状态,减少临床相关症状,进而间接提升CD4^+T淋巴细胞数。  相似文献   
6.
空气质量能够通过情绪渠道和信息渠道去影响投资者的决策和投资行为,从而影响股票市场。采用2014年5月14日至2017年2月17日的上证指数、全国PM2.5指数以及百度指数数据,对空气质量如何影响股票市场及其影响力度进行实证分析。结果显示空气质量能够显著地影响股票市场,且季节性紊乱会加剧这一影响力度。此外空气质量对上证工业指数的影响大于上证综指,表明空气质量对特定行业的影响大于整体市场,而信息获取方式又会影响到影响的方向和力度。  相似文献   
7.
生态环境的可持续性已成为中国经济发展面临的最严峻挑战,持续发展问题的探讨却"外热内冷",表面上被频繁提及,实际上却被严重忽视,除去外部性和"公地悲剧",阻碍可持续发展的"非经济"因素更加复杂。首先,由于环境恶化是一个渐变过程,普遍的短视行为使得文明崩溃的历史总是被遗忘;其次,在现实观念中,对技术过分依赖和敌视两种态度限制了其合理利用;复次,知识无序积累造成学术型无知和错误的知识传播,而片面追求经济增长指标的后果要在长期中才会显现出来;最后,对不受约束的奢侈生活方式的追求导致无止境地向地球索取。因此,实现可持续发展需要彻底的观念变革,建立基于系统性的科学教育体系,以及开放的信息管理。  相似文献   
8.
Abstract

Objective:

To compare the demographics, clinical characteristics and resource utilization of patients with bipolar disorder who required frequent psychiatric interventions (FPIs) with those needing fewer interventions in the Duke Healthcare System database between 1999 and 2005.

Methods:

This retrospective analysis was conducted using electronic medical records of bipolar patients with FPIs, defined as having ≥4 clinically significant events (CSEs) in any 12-month period while in the Duke University Healthcare System. CSEs were composed of emergency room visits, inpatient hospitalizations, or a change in psychotropic medication due to psychiatric symptoms (score ≥4 on the Clinical Global Impressions–Severity scale). Data were compared between patients with and without FPIs.

Results:

Of 632 patients with bipolar disorder 52.5% were identified as having FPIs. These patients were younger and more often female and African American than those with fewer interventions (p?<?0.01 for all). Patients with FPIs were generally prescribed more psychotropic and non-psychotropic medications, utilized more healthcare resources and experienced more psychiatric co-morbidities than those who did not require FPIs (p?<?0.01 for all).

Limitations:

These results are from a single healthcare system and may not be generalizable to all patients with bipolar disorder. This analysis was retrospective and relied on availability of adequate information recording and coding of diagnoses by physicians.

Conclusions:

Patients with bipolar disorder who required FPIs were significantly different from those with fewer clinically defined interventions with respect to their demographic and clinical characteristics and prescribed medications.  相似文献   
9.
The undeniable success of order-maintenance policing (also community policing or broken windows policing) is despite the deficiency in the theory which propelled the practice into policy: Wilson and Kelling's broken windows theory. We discuss what is wrong with the theory and why it nevertheless works when put into practice.  相似文献   
10.
Abstract

Objective: To determine the treatment pattern and impact on healthcare costs of anxiety disorders and major depressive disorder (MDD), and influence of their concomitance and subsequence.

Methods: A retrospective cohort study was conducted using a US reimbursement claims database. Adult patients with an incident diagnosis of anxiety or MDD (index date) were included. Their sociodemographic data, diagnoses, healthcare resource use and associated costs were collected over the 6 months preceding and 12 months following index date.

Results: A total of 599,624 patients were identified and included. Patients with phobia or post-traumatic stress disorder had the highest 12-month costs ($8,442 and $8,383, respectively). Patients with social anxiety disorder had the lowest costs ($3,772); generalized anxiety disorder ($6,472) incurred costs similar to MDD ($7,170). Costs were substantially increased with emergence of anxiety during follow-up in MDD patients ($10,031) or emergence of MDD in anxiety patients ($9,387). This was not observed in patients with both anxiety and MDD at index date ($6,148).

Conclusion: This study confirms the high burden of costs of anxiety, which were within the same range as MDD. Interestingly, the emergence of anxiety or MDD in the year following a first diagnosis of MDD or anxiety, respectively, increased costs substantially. Major limitations were short follow-up and lack of absenteeism costs.  相似文献   
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