基因组方法在虚拟企业组织优化中的应用研究

文章从影响虚拟企业组织设计的权变因素的角度,分析了虚拟企业组织结构设计的特点,并从理论上论证了基因组方法在虚拟企业组织优化设计过程中的适用性。结合组织设计流程,将基因组方法在以特许经营为特征的虚拟企业——美特斯.邦威中进行了试应用,以说明基因组方法在虚拟企业组织优化应用中的有效性。     

人类后基因组研究进展

人类对自身基因组的研究不断发展，已从结构基因组学转向功能基因组学阶段。本文概述了人类后基因组的研究内容及进展状况。     

基因组方法在项目组织结构优化中应用

针对传统项目管理所存在的局限性，以遗传性项目管理知识领域为基础，提出了一种组织结构优化的新方法——基因组方法。系统地阐述了基因组方法实施的前提条件和实施步骤，为企业提高项目管理水平，进行项目管理方法的创新打开了一个新的思路。     

Mapping the emerging field of genome editing

Targeted genetic modification (TagMo) technologies are being used for new approaches to genetic engineering often called ‘genome editing’. These approaches are in the early stages of development, and basic understandings of what TagMo is, of its likely future, and how it should be governed are still being established. In order to inform these discussions and increase their transparency, we map the scientific landscape of TagMo using advances in tech mining and bibliometrics and in consultation with experts in the field. We assess the sub-topics and disciplines associated with TagMo research, and the actors, institutions, and nations involved, while making observations about the funding of research and the collaborative patterns among actors. The technology assessment approach used in this article has important implications for anticipatory governance of TagMo plant products. It is designed to help scientists, managers, and policy-makers understand trends in TagMo technological development in order to prepare for future governance.     

A Review of Statistical Methods for Genome Mapping

Framework maps of the human genome are an important staging post in the on-going effort to sequence the entire genome. The existence of high quality maps is also a prerequistite for studies attempting to determine the location of genes involved in common diseases. The basic experimental approaches to constructing both genetic and physical maps are briefly described as well as their respective uses. A variety of statistical approaches to map construction are outlined including parsimony, maximum likelihood and Bayesian methodologies. The mostly widely used of these, the method of maximum likelihood, is discussed in detail, particularly in the context of physical mapping using radiation hybrids. Finally, current statistical issues and problems in the field of genome mapping are described.     

赤拟谷盗基因组中microRNA的生物信息学预测与进化分析

本文通过计算机编程技术以及预测miRNA的RNAfold和Triplet-SVM软件在赤拟谷盗基因组中预测了43个miRNA。进一步对预测的miRNA进行长度统计以及保守性分析。     

企业业务基因重组

文章对企业的业务基因重组理论进行了研究,对业务基因和组织基因的关系进行了探讨。分析了企业进行业务基因重组的动因;归纳了企业进行业务基因重组的特征;结合实例揭示了企业业务基因重组的具体战略。     

New plant engineering techniques,R&D investment and international trade

New plant engineering techniques (NPETs) may significantly improve both production and quality of foods. Some consumers and regulators around the world might be reluctant to accept such products and the global market penetration of these products may remain low. We develop a parsimonious economic model for R&D investment in food innovations to identify conditions under which NPET technology emerges in the context of international trade. The framework integrates consumers' willingness to pay (WTP) for the new food, the uncertainty of R&D processes, the associated regulatory cost of approval, and the competition between domestic and foreign products. With generic applicability, the model enables the quantitative analysis of new foods that could be introduced in markets and then traded across borders. We apply the framework to a hypothetical case of apples improved with NPETs. Simulation results suggest that import bans and high values of sunk cost can reduce R&D investment in NPETs to suboptimal levels.