The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

近10年日本宏观经济的理论分析与展望

近10年日本经济停滞不前，一方面对外经济状况不佳：日元对美元汇率技术下跌。且不断加剧；出口增长放缓，贸易顺差连续下滑，另一方面国内宏观经济状况严峻；失业率不断上升，内需不振；通货紧缩逐步加深；工业增长持续低迷，工业生产与效益下降，究其原因，用内外均衡模型理论分析得出，日本经济没有达到均衡的0点，内外均衡遭到了破坏，而展望今后的日本经济和日元走势，基于日本财政状况的恶化及货币政策的失效，估计还不会导致资本的大量外流。也不会对资本流动产生重要的影响，而结构改革也将可能引致日元升值。     

对我国上市银行非经常性损益披露的分析和建议

本文通过分析2001至2004年上市银行年报非经常性损益的披露状况,对照监管部门法规,发现存在披露不充分的现象,对非经常性损益的确认也有理解偏颇,由此造成很多重大的可疑事项未计入非经常性损益。本文认为这对银行利润的真实性产生一定的影响,故建议政策制定者制定更详细的法规来规范披露行为,并就一些特殊事项做出释疑。     

On estimating the mean of the selected normal population under the LINEX loss function

Following Parsian and Farsipour (1999), we consider the problem of estimating the mean of the selected normal population, from two normal populations with unknown means and common known variance, under the LINEX loss function. Some admissibility results for a subclass of equivariant estimators are derived and a sufficient condition for the inadmissibility of an arbitrary equivariant estimator is provided. As a consequence, several of the estimators proposed by Parsian and Farsipour (1999) are shown to be inadmissible and better estimators are obtained. Received January 2001/Revised May 2002     

违约损失率问题初探

巴塞尔新资本协议强调内部评级法在风险管理和资本监管中的重要作用。内部评级法的关键在于对违约率及其相关因素的测量,其中违约概率(PD)和违约损失率(LGD)是内部评级法的核心变量。对国际上关于LGD的表现及影响因素的讨论进行了总结与分析,并重点对LGD与PD之间的关系进行了介绍。     

中小私营企业融资中"逆向选择"失灵现象新探

对某些地域中小私营企业融资行为的实证分析表明与常规的设想相反,同国有企业极高的融资热情相比,一般被人们认为风险较大的私营中小企业在融资中存在“逆向选择”失灵的现象。本建立了一个模型对导致此现象的原因进行了探讨。     

中国乡镇企业产出增长来源实证分析

本文简要介绍了中国乡镇企业的发展概况和影响其发展的主要因素 ,以实际总产值作为产出指标 ,对乡镇企业产出增长与全要素生产率增长率、资本投入、劳动投入和规模损益之间的联系进行了详细的实证分析 ,分别考察了技术进步 (全要素生产率增长率 )、资本投入、劳动投入和规模损益对乡镇企业产出增长的绝对拉动作用和相对贡献份额 ,并分别考察了乡镇企业产出增长的波动程度、乡镇企业的资本生产率、劳动生产率及有机资本构成情况。在此基础上 ,提出了保证乡镇企业健康、稳定、持续增长的若干政策建议     

公共经济视角下的国有企业改革分析

国有企业的发展状况表明,单纯从产权方面进行国有企业改革的理论研究和实践是有很大缺陷的,需要从新的视角去探索国有企业的改革思路。之所以从公共经济学的角度去分析国有企业问题,是因为国有企业或多或少具有公共产品的性质,政府对国有企业改革的态度及其行为反映了市场配置资源的能力和国有企业改革所引起的福利改变。     

Using technology to improve the management of development impacts on biodiversity

The mitigation hierarchy (MH) is a prominent tool to help businesses achieve no net loss or net gain outcomes for biodiversity. Technological innovations offer benefits for business biodiversity management, yet the range and continued evolution of technologies creates a complex landscape that can be difficult to navigate. Using literature review, online surveys, and semi-structured interviews, we assess technologies that can improve application of the MH. We identify six categories (mobile survey, fixed survey, remote sensing, blockchain, data analysis, and enabling technologies) with high feasibility and/or relevance to (i) aid direct implementation of mitigation measures and (ii) enhance biodiversity surveys and monitoring, which feed into the design of interventions including avoidance and minimization measures. At the interface between development and biodiversity impacts, opportunities lie in businesses investing in technologies, capitalizing on synergies between technology groups, collaborating with conservation organizations to enhance institutional capacity, and developing practical solutions suited for widespread use.     

风险溢价、预期损失与预测贷款损失准备金

在信贷市场完全信息的假设下,以贷款风险溢价为基础计提的贷款损失准备金能够完全覆盖贷款预期损失.而在经济或行业处于繁荣或上升时期,银行扩张贷款总量、增加长期贷款、放松贷款标准的行为,实际上低估了贷款预期损失.应用马尔科夫链预测理论构建的预测贷款准备金模型,克服了预期现金流折现法、动态准备金法和压力测试准备金法存在的实施难度大、监管制约等缺陷,能够保持银行经营的稳定以及客观地反映盈利状况,可以作为改革贷款准备金政策的参考.