戊二醛急性毒性研究

目的]为了研究人体和环境的潜在危害。方法]对25%戊二醛样本进行了急性经口毒性试验（大鼠、小鼠）、急性经皮毒性试验、急性吸入毒性试验和鱼急性毒性实验研究。结果]戊二醛小鼠经口LD50为248 mg/kg体重,大鼠经口LD50为239 mg/kg体重,经皮LD50≥2000mg/kg体重,急性吸入毒性4h-LC50为768mg/m3,鱼急性毒性96h-LC50为13.5mg/L。结论]戊二醛对人体的吸入危害风险和环境生态危害风险值得重视。

Acute Toxicity Study for Glutaraldehyde

Glutaraldehyde is a volatile and irritate chemical. It may be get into human body by mouth, by skin or by inhalation, and results in the body harm, or results in the fish death when its liquid waste is discharged into Rivers. This study assayed the acute toxicity of glutaraldehyde by the three exposure routes of body, and assayed fish acute toxicity. The results show that the LD50 （ or LC50 ） is 248 mg/kgbw（ mice, by mouth）, 239 mg/kgbw（ rat, by mouth）, ≥2000mg/kgbw （rat, by skin）, 768mg/m3 （ mice, by inhalation） and 13. 5mg/L （fish, 96h - LC50. ）. According to the acute toxicity grades, the acute toxicity of Glutaraldehyde by mouth, by inhalation and the fish toxicity belong to medium toxicity. According to experimental results, it is well worth further research on the toxicity of inhalation and fish toxicity.