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Market challenges facing academic research in commercializing nano-enabled implantable devices for in-vivo biomedical analysis
Authors:E Juanola-Feliu  J Colomer-Farrarons  P Miribel-Català  J Samitier  J Valls-Pasola
Institution:1. Department of Electronics, Bioelectronics and Nanobioengineering Research Group (SIC-BIO), University of Barcelona, Martí i Franquès 1, Planta 2, 08028 Barcelona, Spain;2. IBEC-Institute for Bioengineering of Catalonia, μnanosystems Engineering for Biomedical Applications Research Group, Baldiri Reixac 10-12, 08028 Barcelona, Spain;3. CIBER-BBN-Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, María de Luna 11, Edificio CEEI, 50018 Zaragoza, Spain;4. Department of Economics and Business Organization, University of Barcelona, Av. Diagonal 690-696, 08034 Barcelona, Spain;1. Faculty of Dentistry, The University of Hong Kong, Hong Kong, China;2. Industrial Centre, The Hong Kong Polytechnic University, Hong Kong, China;3. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China;1. Hogeschool-Universiteit Brussel and KU Leuven, Brussels, Belgium;2. Belgian Science Policy Office, Brussels, Belgium;1. Department of Health Administration, Virginia Commonwealth University, PO Box 980203, Richmond, VA 23298-0203, USA;2. Department of Health Administration, Virginia Commonwealth University, 1008 East Clay Street, PO Box 980203, Richmond, VA 23298-0203, USA
Abstract:This article reports on the research and development of a cutting-edge biomedical device for continuous in-vivo glucose monitoring. This entirely public-funded process of technological innovation has been conducted at the University of Barcelona within a context of converging technologies involving the fields of medicine, physics, chemistry, biology, telecommunications, electronics and energy. The authors examine the value chain and the market challenges faced by in-vivo implantable biomedical devices based on nanotechnologies. In so doing, they trace the process from the point of applied research to the final integration and commercialization of the product, when the social rate of return from academic research can be estimated. Using a case-study approach, the paper also examines the high-tech activities involved in the development of this nano-enabled device and describes the technology and innovation management process within the value chain conducted in a University–Hospital–Industry–Administration–Citizens framework. Here, nanotechnology is seen to represent a new industrial revolution, boosting the biomedical devices market. Nanosensors may well provide the tools required for investigating biological processes at the cellular level in vivo when embedded into medical devices of small dimensions, using biocompatible materials, and requiring reliable and targeted biosensors, high speed data transfer, safely stored data, and even energy autonomy.
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