Sequential estimation in generalized linear models when covariates are subject to errors

Sequential methods have been used for many applications; especially, when fixed sample procedures are not possible and/or when “early stopping” of sampling is beneficial for applications. At the same time, the issue of how to make correct inferences when measurement errors are present has drawn considerable attention from statisticians. In this paper, the problems of sequential estimation of generalized linear models when there are measurement errors in both adaptive and fixed design cases are studied. The proposed sequential procedure is proved to be asymptotically consistent and efficient in the sense of Chow and Robbins Ann Math Stat 36(2):457–462, 1965] when measurement errors decay gradually as the number of sequentially selected design points increases. This assumption is useful in sequentially designed experiments, and can also be fulfilled in the case when replicate measurements are available. Some numerical studies based on a Rasch model and a logistic regression model are conducted to evaluate the performance of the proposed procedure.