Exact and approximate D-optimal designs in polynomial regression

If the sample sizen is large enough, then the exact polynomial regression designs obtained by rounding the weights of the approximate D-optimal design to integral multiples of 1/n are D-optimal. This was shown by alaevskiî (1966) and Gaffke (1987). In this note, an efficient algorithm to determine the minimum sample sizen _d for a polynomial model of degreed is derived from a condition given by Huang (1987). Under an additional assumption we show that the conditions of Gaffke and Huang are equivalent; we verify the additional assumption for polynomial degreed40.