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硫唑嘌呤联合小剂量曲安西龙治疗老年慢性免疫性血小板减少症的疗效观察
引用本文:焦宗久,郭素丽,陈娜飞.硫唑嘌呤联合小剂量曲安西龙治疗老年慢性免疫性血小板减少症的疗效观察[J].中国药物经济学,2014(6):29-31.
作者姓名:焦宗久  郭素丽  陈娜飞
作者单位:河北省邢台市人民医院血液科,河北邢台054031
摘    要:目的探讨硫唑嘌呤联合小剂量曲安西龙治疗老年慢性免疫性血小板减少症(CITP)的疗效,并观察其不良反应。方法 56例非重症的老年CITP患者,随机分为治疗组及对照组,治疗组给予口服硫唑嘌呤1.5mg/kg/d及曲安西龙片20mg/d治疗,对照组仅口服强的松1mg/kg/d治疗。结果治疗6个月后,治疗组总有效率(79.3%)高于对照组(51.9%),治疗组血小板均值高于对照组。结论硫唑嘌呤联合小剂量曲安西龙治疗老年性CITP有效率高,毒副作用少。

关 键 词:老年慢性免疫性血小板减少症  硫唑嘌呤  曲安西龙片  血小板计数

Clinical curative effect Observation of Azathioprine Combined with low dose of Triamcinolone Tablets in Treatment of Senile Chronic Immune Thrombocytopenia
Jiao Zongjiu,Guo Suli,Chen Nafei.Clinical curative effect Observation of Azathioprine Combined with low dose of Triamcinolone Tablets in Treatment of Senile Chronic Immune Thrombocytopenia[J].China Journal of Pharmaceutical Economics,2014(6):29-31.
Authors:Jiao Zongjiu  Guo Suli  Chen Nafei
Institution:Jiao Zongjiu,Guo Suli,Chen Nafei
Abstract:Objective To evaluate the clinical effect of azathioprine combined with smal dose of triamcinolone tablets in the treatment of senile chronic immune thrombocytopenia (CITP) patients,and to observe the adverse reactions.Methods Al 56 patients with CITP,were randomized into the treatment group and the control group:the treatment group was treated with azathioprine 1.5mg/Kg/d and triamcinolone tablets 20mg/d,the control group with prednisone 1mg/kg/d.Resaults After 6 months treatment,the effective rate of the treatment group(79.3%) was much higher than that of the control group(51.9%).The average platelet count of the treatment group is much higher than that of the control group.Conclusion The treatment of azathioprine combined with smal dose of triamcinolone tablets in the senile CITP has a good curative effect,and has no obvious adverse reaction.
Keywords:Chronic immune thrombocytopenia  Azathioprine  Triamcinolone tablets  Platelet count
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