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Securing the Sustainability of Global Medical Nuclear Supply Chains Through Economic Cost Recovery,Risk Management,and Optimization
Authors:Anna Nagurney  Ladimer S. Nagurney  Dong Li
Affiliation:1. Department of Operations and Information Management, Isenberg School of Management, University of Massachusetts, Amherst, Massachusetts, USA;2. School of Business, Economics and Law, University of Gothenburg, Gothenburg, Swedennagurney@isenberg.umass.edu;4. Department of Electrical and Computer Engineering, University of Hartford, West Hartford, Connecticut, USA
Abstract:
In this paper, we develop a new generalized network model for the optimization of the complex operations of medical nuclear supply chains in the case of the radioisotope molybdenum, with a focus on minimizing the total operational cost, the total waste cost, and the risk associated with this highly time-sensitive and perishable, but critical, product used in health-care diagnostics. Our model allows for the evaluation of transitioning the production and processing of the radioisotope from highly enriched uranium targets to low enriched uranium targets. A case study for North America demonstrates how our model and computational framework can be applied in practice.
Keywords:generalized networks  health-care security  molybdenum  multicriteria decision-making  nuclear medicine  optimization  radioactive decay  risk management  supply chains  sustainable transportation  time-sensitive products  variational inequalities
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