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A Unifying Framework for Marginalised Random‐Intercept Models of Correlated Binary Outcomes
Authors:Bruce J Swihart  Brian S Caffo  Ciprian M Crainiceanu
Institution:Johns Hopkins Bloomberg School of Public Health, , Baltimore, MD, 21205 USA
Abstract:We demonstrate that many current approaches for marginal modelling of correlated binary outcomes produce likelihoods that are equivalent to the copula‐based models herein. These general copula models of underlying latent threshold random variables yield likelihood‐based models for marginal fixed effects estimation and interpretation in the analysis of correlated binary data with exchangeable correlation structures. Moreover, we propose a nomenclature and set of model relationships that substantially elucidates the complex area of marginalised random‐intercept models for binary data. A diverse collection of didactic mathematical and numerical examples are given to illustrate concepts. Copyright © 2013 John Wiley & Sons, Ltd.
Keywords:Binary outcomes  copulas  marginal likelihood  multivariate logit  multivariate probit
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