| 非甾体抗炎药(NSAIDs)的新进展 |
| |
| 引用本文： | 傅德才,王淑月,荣杰,张守芳.非甾体抗炎药(NSAIDs)的新进展[J].河北工业科技,2004,21(3):55-57. |
| |
| 作者姓名： | 傅德才 王淑月 荣杰 张守芳 |
| |
| 作者单位： | 河北科技大学化学与制药工程学院,河北石家庄,050018;河北医科大学药学院,河北石家庄,050017;沈阳药科大学制药工程学院,辽宁沈阳,110015 |
| |
| 摘 要： | NO是细胞间重要的信使物质,具有多种生理作用;将释放NO的物质与传统的非甾体的抗炎药连接起来,在保证疗效的情况下有可能克服传统的非甾体抗炎药的胃肠道副作用,因此有可能成为高效低毒的新非甾体抗炎药。20世纪90年代以来,NO释放型的非甾体抗炎药研究取得了很大进展,现就这方面的研究情况作一简要综述。
|
| 关 键 词： | 非甾体抗炎药 前列腺素 NO 进展 |
| 文章编号： | 1008-1534(2004)03-0055-03 |
| 修稿时间： | 2002年10月14 |
The New Development of the Non-steroid Anti-inflammatory Drugs (NSAIDs) |
| |
| FU De-cai,WANG Shu-yue,RONG Jie,ZHANG Shou-fang.The New Development of the Non-steroid Anti-inflammatory Drugs (NSAIDs)[J].Hebei Journal of Industrial Science & Technology,2004,21(3):55-57. |
| |
| Authors: | FU De-cai WANG Shu-yue RONG Jie ZHANG Shou-fang |
| |
| Institution: | FU De-cai~1,WANG Shu-yue~2,RONG Jie~1,ZHANG Shou-fang~3 |
| |
| Abstract: | The development of new non-steroid anti-inflammatory drugs (NSAIDs) with high efficiency and minimal toxicity is based on the discovery of NO , which is an important message substance and has various physiological effects. Compounds which combine traditional non-steroid anti-inflammatory drugs with NO-releasing substance would become new NSAIDs . The study has achieved a great development since 1990s. A brief review is presented. |
| |
| Keywords: | NSAIDs PGs NO development |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
