刺芪参胶囊的制备工艺研究 |
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作者姓名: | 王晓林 戴鹂莹 邸松 钟方丽 |
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作者单位: | 吉林化工学院化学与制药工程学院,吉林 吉林 132022 |
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基金项目: | 吉林省科技厅重点科技攻关项目(编号:20170204001YY);吉林省教育厅“十三五”科学技术项目(编号:JJKH20170225KJ)。 |
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摘 要: | 目的:探索刺芪参胶囊的制备工艺。方法:采用正交实验,以总皂苷质量为指标,优化提取工艺;采用单因素实验优化制剂工艺。结果:在最佳提取工艺条件下,刺芪参胶囊提取物中的总皂苷含量为12.19 mg·g-1;以糊精作为填充剂、硬脂酸镁为助流剂、95%乙醇为黏合剂制备胶囊剂。结论:刺芪参胶囊的制备工艺稳定可行。
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关 键 词: | 人参 黄芪 刺玫果 胶囊 正交实验 |
Study on Preparation Technology of CIQISHEN Capsule |
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Authors: | Wang Xiaolin Dai Liying Di Song Zhong Fangli |
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Institution: | (School of Chemistry and Pharmaceutical Engineering,Jilin Institute of Chemical Technology,Jilin 132022,China) |
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Abstract: | Objective:To explore the preparation technology of ciqishen capsule.Methods:The extraction process was optimized with the quality of total saponins as the index by orthogonal;Single factor experiment was used to optimize the preparation process.Results:Under the optimal extraction conditions,the content of total saponins in the extract of ciqishen capsule is 12.19 mg·g-1;The capsules were prepared with slushee as filler and magnesium distearate as flow aid and 95%as binder.Conclusions:The preparation technology of ciqishen capsule is stable and feasible. |
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Keywords: | Ginseng Astragalus Fruit of Rosa davurica Pall Capsule Orthogonal experiment |
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