Strategic alignment and organizational options in biotechnology firms

Biotechnology has created a number of oflfiortunities for new start-up firms. A feu of these fims have grown rapidly and have ambitious strategies. These strategies reflect the fim growing organizational competences i n the context of rapidly changing technological, competitive, Jinanczal and regulatory circumstances. The firms have pursued adaptive, learning-based strategies which give them advantages over large firms. Underpinning these strategies have been long-term efforts to establish a highly motivated and creative workforce. Using the examples fo the UK's two leading biotechnology firms, some of the features of these strategies are exumined. It is found that there are dgerences i n the organizational forms selected by the two fims. These reflect temporal factors, differing environmental conditioru, and elements of manugement choice. The difficulty oj strategic management in turbulent conditions 6s highlighted by considering some of the strengths and weaknesses of both options.     

Broad-based employee stock options grants and IPO firms

This paper examines the broad-based grant of employee stock options (ESOs) in the period following the Initial Public Offering (IPO). Stock option grants are used to reduce the negative effects of conflicts of interests associated with a firm's going public. The study documents that option grants can be seen as corporate governance instruments for a number of model specifications. Also, it is found that there is a robust relation between option grants and market and accounting returns, respectively. To the best of the authors' knowledge, no previous study has investigated the determinants of the grants of employee stock options in the post-IPO period to both upper-level and lower-level executives during a period of sixteen years. Because the cross-sectional data of this study amply encompasses more than a business cycle it is possible to examine the grants of ESOs across tight and soft labour markets. During the former type of labour market it appears that more options are granted. Also, the empirical results provide evidence that option grants are an increasing function of the employees’ benefits for the firm. Finally, the findings show that cash constrained firms appear to use employee stock option grants in place of cash compensation.     

Marketing and r&d strategies for biotechnology firms in the usa

This pape reports on a survey of 64 biotechnology firms in the USA about their R&D strategy, marketing focud and sources of technology. The survey explored the interrelationships among the strategic issues and how they were related with the means of appropriating R&D results. Three stralegic clusters for technology acquisitin emerged from the data: (i) internal developer, (ii) joint developer, and (iii) cooperative financed. Three marketing clusters were: (i) market penetartor, (ii) innovative marketer, and (iii) market developer. The R&D clusters were: (i) defensive strategy, (ii) aggressive strategy, and (iii) research-intensive strategy. External sources of technology appeared to be predominant among thje various firms and apparently marketing strategy and source of technology had no significant relationship. Most of the firms were involved with commercial innovation in their R&D strategy and few were research specialists. Innovative firms were inclined to depend on external sources sources of technology. Issues related to appropriability of R&D results for the different groups have been examined for their implications for public policy.     

Marketing and r&d strategies for biotechnology firms in the usa

This pape reports on a survey of 64 biotechnology firms in the USA about their R&D strategy, marketing focud and sources of technology. The survey explored the interrelationships among the strategic issues and how they were related with the means of appropriating R&D results. Three stralegic clusters for technology acquisitin emerged from the data: (i) internal developer, (ii) joint developer, and (iii) cooperative financed. Three marketing clusters were: (i) market penetartor, (ii) innovative marketer, and (iii) market developer. The R&D clusters were: (i) defensive strategy, (ii) aggressive strategy, and (iii) research-intensive strategy. External sources of technology appeared to be predominant among thje various firms and apparently marketing strategy and source of technology had no significant relationship. Most of the firms were involved with commercial innovation in their R&D strategy and few were research specialists. Innovative firms were inclined to depend on external sources sources of technology. Issues related to appropriability of R&D results for the different groups have been examined for their implications for public policy.     

Strategic planning III: Objectives and program options

This series of papers deals with technological forecasting in strategic planning. In the first paper the author examines forecasting and planning as a process, identifying five roles of forecasting (1) Identifying policy options; (2) Aiding strategy formulation; (3) Identifying program options; (4) Selecting programs for funding, and (5) Selecting opportunities for funding. The subsequent papers deal primarily with the first and third roles.The second paper of the series describes perspective trees—a form of relevance tree—for identifying policy options. A perspective tree is used to interrelate sets of social, economic, political, and technological forecasts that pote threats and present opportunities for strategic consideration.The third paper of the series describes the use of objective trees in structuring program options for selected strategies. R&D programs as well as marketing and other functional business programs are structured—clarifying options for the decision-making process.     

Strategic tariffs, tariff jumping, and heterogeneous firms

The majority of research to date investigating strategic tariffs in the presence of multinationals finds a knife-edge result where, in equilibrium, all foreign firms are either multinationals or exporters. Utilizing a model of heterogeneous firms, we find equilibria in which both pure exporters and multinationals coexist. We utilize this model to study the case of endogenously chosen tariffs. As is standard, Nash equilibrium tariffs are higher than the socially optimal tariffs. Unlike existing models with homogeneous firms, we find that non-cooperative tariffs promote the existence of low-productivity firms relative to the socially optimal tariffs. This highlights a new source of inefficiency from tariff competition not found in models of homogeneous firms. In addition, we find that in many cases the Nash equilibrium tariff when FDI is a potential firm structure is lower than when it is not. As a result, FDI improves welfare by mitigating tariff competition.     

Strategic commitment and Cournot competition with labor-managed and profit-maximizing firms

This paper examines the behavior of a labor-managed income-per-member-maximizing firm and a profit-maximizing firm in a quantity-setting model with a strategic commitment. First, each firm independently decides whether or not to make a commitment to capacity. This capacity may subsequently be increased, but cannot be decreased. Hence, each firm’s investment choice changes its capital cost from a variable one into a fixed one. Second, each firm independently chooses its actual output. The paper examines the equilibrium of the quantity-setting mixed model and shows whether or not capacity investment is effective for the labor-managed firm and the profit-maximizing firm.     

Strategic use of futures and options by commodity processors

The impacts of input–output price relationships on end-users' demands for positions in futures and options are analyzed using a mean-variance portfolio model and applied to price risk management in the bread manufacturing industry. A production relationship was assumed between the input and resultant output, and correlation between the input and output prices were introduced into the portfolio model. The optimal hedge ratio can be either positive or negative depending upon the relationship between the input and output price standard deviation adjusted for production technology and input–output price correlation. Introduction of a call option into the portfolio (in addition to the futures) does not change the hedging demand for futures; however, the speculative component changes. The results show that the addition of input–output linear production and price correlation relationships would not justify a hedging role for options unless there is bias in the futures and/or options markets.     

Strategic foresight and organizational learning: A survey and critical analysis

Learning phenomena are a growing concern for strategic foresight, especially with respect to the question of integration of reflection and action. Although an agreement seems to emerge between practitioners and theorists about strong ties linking strategic foresight and learning (in particular organizational learning), the true nature of this link remains ambiguous. This article seeks to shed light on this link and to analyze the cognitive dimensions of foresight through a critical survey. The investigation follows the original ambivalence between foresight attitude and activity thus underscoring not only the virtues of foresight in learning phenomena, but also the limits of the usual literature.     

扩大对非洲直接投资的策略选择

非洲大陆拥有丰富的资源和巨大的市场潜力,近年来西方国家重新关注非洲,将它视为"世界投资领域的最后一块处女地",并纷纷调整对非政策,对非关系重点由政治转向经济,由援助转向投资和贸易.我国作为世界上最大的发展中国家,拥有与非洲各国深厚的友谊.加强对非洲的直接投资不仅符合我国和非洲国家各自的经济发展需要,而且有利于加强南南合作,建立公正合理的国际政治经济新秩序.     

Technological competence and the influence of networks: a comparative analysis of new biotechnology firms in france and britain

The objective of this paper is to examine the role of external networks not only as a resource but also as a constraint for the evolution ofthe technological competence of twenty new biotechnology firms (NBFs) in France and Britain. The analysis is bared on extensive interviews conducted with the Chief Executive Officers (CEOs) of twenty NBFs, ten in France and ten in Britain. The paper identifies the network structures ofthe tweng NBFs and the impact of netmorks on the evolution of their technologial competence. The paper also attempts to identify the differences between NBFs in France and Britain in terms of the framework developed. It clearly illustrates that the capacity of NBFs to construct appropriate external linkages with other firms andfinanckrs is crucial to their success.     

Strategic analysis of the competitive exercise of certain financial options

Warrants and convertible bonds are claims on the firm which change the outstanding number of common stock shares when exercised or converted. Exercise of such claims in competitive circumstances is modeled here as a noncooperative game played by a continuum of players. First, equilibria of the game are shown to exist by applying results of Schmeidler. Second, the game's equilibria are compared to outcomes that come about when one individual controls the exercise of all the claims, but is constrained to exercise them in one block. The results are analogues of earlier results by one of the authors on the competitive pricing of such claims.     

Why do firms adopt CEO stock options? Evidence from the United States

This paper examines the determinants of stock option introduction as a part of CEO compensation in listed US firms during the 1994–2004 period. The results are consistent with agency costs and recruiting considerations, suggesting that firms do not adjust CEO compensation in order to address the ‘investment horizon’ problem. The findings also suggest that CEO stock option adoption is not necessarily influenced by the same factors that have been found in the literature to affect the level of CEO stock option compensation and the adoption of broad-based stock option incentives. Overall, the findings provide evidence for several theoretical predictions, thus adding to our understanding of managerial incentives.     

Strategic adjustment between innovation and production: generation of integrated archetypes in Spanish service firms

This paper investigates empirically the strategic alignment between innovation and production strategies in a sample of service firms in Spain. It employs the integrated archetypes approach to analyse a dataset of unique, manually collected, firm responses. The results highlight differences in behaviour patterns underpinning both kinds of strategic decisions and, coherent with alignment theory, differential firm performance.     

水电设计咨询业：现状、发展与挑战

加入WTO在给中国国民经济各行业提供更多机遇的同时，也带来了巨大的挑战。作为国民经济命脉的重要基础产业之一的水电行业也是如此。中国欣欣向荣的水电业是国外水电设计咨询巨头们觊觎已久的一块大蛋糕；而拥有雄厚技术实力的中国水电设计咨询部门亦想在国外的水电市场上一展     

Innovation,product development and market value: evidence from the biotechnology industryinnovation in biotechnology industry

The subject of the paper is financial valuation of firm's knowledge assets and returns to innovation in the biotechnology industry, where such assets appear to play key role in the commercial success of a product. The biotechnology industry is extremely research-intensive, and successful R&D drives profitability. Further, the pharmaceutical product development advances in a number of well-defined stages that allow relatively precise measurement of product development outcomes. The study reports recent biotechnology R&D statistics, and provides estimates of private returns to innovation and product development activity in the biotechnology industry. The conclusions indicate that the financial market recognizes the value of drugs in product development stage, as it expects the innovative knowledge embodied in drug development projects to become marketable products in the future.     

Innovation in large and small firms

We find that while there is no unambiguous support for the Schumpeterian hypothesis, the determinants of innovation are generally similar for large and small firms.     

Employee opportunism and redundancy in firms

Firms who share specialized information or client connections with their employees expose themselves to the risk of opportunism, in which their workers leave the firm and go into business for themselves. Legal and contractual solutions to the problem of employee opportunism are not always viable. Instead, firms may organize themselves so as to discourage opportunism. We study an organizational scheme called internal redundancy: the practice of assigning employees to overlapping tasks so that they are less likely to possess sole access to trade secrets or customers, and therefore, less likely to profit if they leave the firm.