Employment transitions and computer use of older workers

Our empirical analysis studies the impact of computer use on out of employment transitions of older workers, disentangling the effect of using a Personal Computer (PC) at work from that of being PC literate. Data are drawn from the 2000, 2002 and 2004 waves of the Bank of Italy Survey on Household Income and Wealth. We provide empirical evidence that, even controlling for a wide set of covariates, older employees who use a PC at work have a higher probability of remaining employed in the future. However, our results also indicate that, once PC literacy is controlled for, the use of a PC at work decreases only marginally the risk of becoming not employed (i.e. the effect is smaller than the one registered when we do not control for PC literacy).     

A theory of classification and evolution of technologies within a Generalised Darwinism

This paper here proposes a theory of classification and evolution of technology based on taxonomic characteristic of interaction between technologies that is an under-studied field of research in economics of technical change and management of technology. The proposed classification of technologies, in a broad analogy with evolutionary ecology of parasites, within a theoretical framework of Generalised Darwinism, is: (1) parasitic technologies, (2) commensal technologies, (3) mutualistic technologies, (4) symbiotic technologies. This theory here suggests the property of mutual benefaction from interaction between different technologies and the theorem of not independence of any technology to explain and predict characteristics and evolutionary pathways of technologies over time. Overall, then, this study may be useful for bringing a new perspective in economics of innovation to categorise and analyse the interaction between technologies that can be a ground work for development of more sophisticated concepts to explain and predict the evolution of technology and generalise aspects of technological change in human society.     

Collective knowledge production costs and the dynamics of technological systems

Technological knowledge can be understood as a collective good only when its production requires the absorption and integration of external knowledge. Such external knowledge is the outcome of R&D investments that cannot be fully appropriated by firms and generate spillovers. The exploitation of such knowledge spillovers requires specific investments in knowledge communication and absorption, which brings about specific costs. These costs are affected by the structural and dynamic characteristics of technological systems in terms of the knowledge base, the variety of actors and the communication infrastructures and processes. This paper analyzes the costs of collective knowledge production and their implications for the way in which the firm chooses the mix of internal and external knowledge. This choice in turn shapes the evolution of technological systems.     

Limits to creative destruction and technologies in practice: the case of ham radio

Drawing on the structurationist notion of ‘technologies-in-practice’, this article analyses the different types of technological actions that users perform, after technological change, in order to keep a declining technology alive over time. The research question of the article is: How do technologies-in-practice based on the application of new technology hamper the creative destruction of old technology? The case study of ham radio technology and amateur radio operators is explored. The results of the investigation support the development of a technology-in-practice ‘experimentation’ and four inductive research propositions.     

关于中国公务员与企业职工养老保险制度并轨的思考

近年来,专家学者们越来越关注两种养老保险制度并轨的问题,养老制度的改革迫在眉睫,国家应积极促进公务员与企业职工养老保险制度的并轨,同时坚持社会公平的原则,兼顾国家当前和长远的稳定发展,逐渐探索出两种制度顺利并轨的方式。这样养老保险制度才能健康有序的发展下去,才能更好地实现稳定社会的功能。     

Stimulating different types of eco-innovation in the UK: Government policies and firm motivations

In this paper, we adopt a recent OECD framework and examine the role of external policy tools and internal firm specific factors for stimulating three different types of eco-innovations that range on a spectrum of lower to higher technological and environmental impacts: End-of-Pipeline Pollution Control Technologies, Integrated Cleaner Production Technologies and Environmental R&D. Using a novel firm-level dataset from a DEFRA survey, we estimate a Tobit model, which provides empirical evidence showing that these eco-innovations are motivated by different external policy tools and internal firm specific factors. Our findings indicate that End of Pipeline Technologies and Integrated Cleaner Production Technologies are mainly driven by equipment upgrade motives with a view of improving efficiency while environmental regulations are effective in stimulating the End-of-Pipeline technologies and Environmental R&D. Interestingly, alongside government induced regulations, we find that market factors, mainly motivated by cost savings, are effective in driving Environmental R&D. Finally, ISO14001 certification is effective in strengthening the positive impact of environmental management systems on both End-of-Pipeline technologies and Environmental R&D while CSR policies have no significant impact on motivating any of the eco-innovations.     

基于资源的知识型企业技术创新能力评价模型及其应用

通过对企业资源与企业技术创新能力关系的辨析,本文认为,知识型企业的技术创新能力与其获取和开发资源的能力严格相关,通过分析企业在其生命周期内经营的特定资源的种类和数量就可评价企业的技术创新能力。在此基础上,构建了基于资源的知识型企业技术创新能力评价指标体系和综合评价模型,并对实例企业的技术创新能力进行了综合评价。     

Military Planning in a Context of Complex Systems and Climate Change

The task of the U.S. military will continue to grow due to destruction from climate change across the globe. Climate change has caused the loss of military bases due to the ocean rising, and caused drought, more intense storms, and hunger, all of which has led to ethnic cleansing, mass migration, the destruction of institutions, and war in global perspective. Violence will continue to grow at a rate faster than the military’s ability to cope without a change in purposeful planning. Two concerns stressed at the week-long consortium, in which I recently participated at the U.S. Army War College, were (i) the substantial military burden due to climate change and (ii) the need to use the principles of complex systems in planning. Thus, the military needs to reach into areas devastated by climate change in order to reduce the likelihood of violence, and to use the correct understanding of complex systems principles for military planning to prevent war.     

资源计划管理是项目成功的重要基础

资源是项目实施的最根本保证,包括自然资源和人造资源、内部资源和外部资源、有形资源和无形资源,知识作为无形资源的价值表现的更加突出。项目管理是实现组织战略计划的一种手段,项目管理能力直接影响项目的成功与否。通过对企业的多种资源进行计划,实现物流、资金流和信息流的统一,实现企业净利润的最大化。     

Opening a policy window for organisational change and full-cost accounting: The creation of BC Hydro's water use planning program

British Columbia's Water Use Planning (WUP) program is a multi-stakeholder process that revises the operating plans of BC Hydro's hydroelectric facilities in order to consider water values beyond hydropower. Using a model of policy change, this paper analyses the circumstances that enabled the emergence of WUP and prompted BC Hydro to change its decision-making processes to better consider environmental and social concerns.External factors, including dam operations' ecological impacts, an imprecise regulatory environment, and worsening relationships with regulators, highlighted the need for a change in operating BC Hydro facilities. Factors internal to BC Hydro included the development of a business case, concerns regarding the utility's reputation and public expectations. While different approaches were explored for solving BC Hydro's problems, a policy window for change opened within a shifting context provided by the election of a more progressive government, the growth of the environmental movement, and new approaches to taking complex multi-stakeholder, multiple resource decisions. Following a successful pilot process and government direction to expand WUP, factors that enabled its institutionalisation included financial resources to compensate for the foregone power, the presence of visionary individuals, the background preparation that facilitated a successful pilot WUP, and the urgent need of a solution.     

我国自然资源产权制度变迁和改革绩效评价

文章从自然资源产权的初始界定出发,考察我国改革开放以来自然资源产权制度改革的两个阶段,在此基础上指出我国自然资源改革的成效以及现行自然资源产权制度存在的主要问题.     

New technology and old institutions: An empirical analysis of the skill-biased demand for older workers in Europe

Using panel data from nine European countries over the period 1970 to 2007, we examine the impact of information and communication technology (ICT) on the demand for older workers (aged 50 and over). We find evidence of a decrease in demand for older workers in the 1970s and 1980s. It can be argued that the impact of ICT on demand for older workers is skill-biased. However, the skill-biased demand for older workers is mainly reflected in the skill-biased changes in employment shares rather than relative wages. There is some evidence of a gradual deskilling of older workers. We find that labour market institutions such as the national minimum wage, social pacts on wage issues and union density mostly benefit skilled older workers, while coordination of wage setting, extension of collective agreements, social pacts on pensions and centralisation of wage bargaining can alleviate the adverse effects of skill-biased technological change.     

The opportunity cost of land use and the global potential for greenhouse gas mitigation in agriculture and forestry

This paper analyses the role of global land management alternatives in determining potential greenhouse gas mitigation by land-based activities in agriculture and forestry. Land-based activities are responsible for over a third of global greenhouse gas emissions, yet the economics of land-use decisions have not been explicitly modeled in global mitigation studies. In this paper, we develop a new, general equilibrium framework which effectively captures the opportunity costs of land-use decisions in agriculture and forestry, thereby allowing us to analyse competition for heterogeneous land types across and within sectors, as well as input substitution between land and other factors of production. When land-using sectors are confronted with a tax on greenhouse gas emissions, we find significant changes in the global pattern of comparative advantage across sectors, regions, and land types. Globally, we find that forest carbon sequestration is the dominant strategy for GHG emissions mitigation, while agricultural-related mitigation comes predominantly from reduced methane emissions in the ruminant livestock sector, followed by fertilizer and methane emissions from paddy rice. Regionally, agricultural mitigation is a larger share of total land-use emissions abatement in the USA and China, compared to the rest of the world, and, within agriculture, disproportionately from reductions in fertilizer-related emissions. The results also show how analyses that only consider regional mitigation, may bias mitigation potential by ignoring global market interactions. For example, USA-specific analyses likely over-estimate the potential for abatement in agriculture. Finally, we note that this general equilibrium framework provides the research community with a practical methodology for explicit modeling of global land competition and land-based mitigation in comprehensive assessments of greenhouse gas mitigation options.     

Medical resource use and cost of different first-line treatments for metastatic colorectal cancer in Brazil

Abstract

Background: Metastatic colorectal cancer (mCRC) is one of the most common malignancies worldwide. The availability of new chemotherapeutic agents have modified the treatment of mCRC over the years creating the need to evaluate the financial impact of treatment. The aim of this study was to establish and quantify the financial resources needed during the first-line treatment of mCRC in Brazil.

Methods: The authors began by reaching expert consensus using a modified Delphi panel with oncologists working at public and private services in Brazil. Costs were calculated using official databases and the microcosting technique.

Results: The panel reached consensus on six regimens used in the first-line treatment of mCRC, as well as the resources involved in the administration of these regimens. All the regimens contain either fluorouracil (5-FU)/leucovorin or capecitabine, combined with either oxaliplatin or irinotecan. The analysis showed that, when compared with intravenous 5-FU/leucovorin, the cost of capecitabine was offset by administration costs.

Conclusion: The panel concluded that regimens containing capecitabine, especially capecitabine plus oxaliplatin (XELOX) are less expensive than those containing 5-FU/leucovorin. Given the comparable efficacy and good tolerability of the XELOX regimen, it may be an attractive choice for the first-line treatment of Brazilian patients with mCRC.     

The temporal dynamics of technology promises in government and industry partnerships for digital innovation: the case of the Copyright Hub

What is the expectation work required to ensure that technological innovation initially supported by government funding is subsequently taken up by market actors? This paper explores this question by applying a linked ecologies framework to the study of the Copyright Hub, a digital infrastructure for Intellectual Property trading developed in the UK. We draw our analysis from a five year long study, including forty-six interviews and six weeks of participant observation. We found that expectation work in policy-led infrastructural communities entails (1) leveraging technology to reshape the position of actors in the innovation space; (2) exploiting the different temporalities of expectation work in allied ecologies and (3) mobilising ‘slow’ expectations to provide momentum to the newly arranged innovation space. Highlighting difference in temporal dynamics for the various partners involved as a ‘hinging’ factor, our analysis contributes to clarifying the complex temporal alignment of policy and innovation processes in technology projects.     

Cost-utility of celecoxib use in different treatment strategies for osteoarthritis and rheumatoid arthritis from the Quebec healthcare system perspective

Abstract

Objective: To assess the cost-utility of celecoxib in three treatment strategies for arthritis in Quebec, considering both upper gastrointestinal (GI) and cardiovascular (CV) events.

Methods: A Markov analytic framework was used to model patients with osteoarthritis and rheumatoid arthritis at low/average and high risk of GI and CV toxicity over 5 years with monthly cycles. Treatment strategies were modelled in line with Canadian clinical practice. In first-line treatment, patients started on celecoxib; second-line, patients started on a non-selective non-steroidal anti-inflammatory drug (NSAID) and switched to celecoxib after a first GI event; third-line, patients started on a non-selective NSAID, added a proton pump inhibitor (PPI) after a first GI event, and switched to celecoxib after a second GI event (while maintaining the PPI). Model inputs were determined through comprehensive literature searches (MEDLINE and EMBASE) from 1995 to 2006. Included studies evaluated GI (dyspepsia, uncomplicated and complicated ulcers, death) and CV (myocardial infarction, stroke, death) events. Drug and procedure costs were derived from Canadian published sources (Can$2005).

Results: Total costs per patient for celecoxib first-, second-, and third-line treatment were Can$4,790, $3,390, and $3,466, and total quality-adjusted life-years (QALY) were 3.251, 3.231, and 3.230, respectively. In all risk categories, celecoxib second-line was less costly and as effective as celecoxib third-line, producing savings to the healthcare system. Although celecoxib first-line generated incremental expenditures versus celecoxib second-line, it was also more effective. The resulting cost-utility ratio for the high-risk population was Can$54,696/QALY. Based on this analytical approach, a treatment strategy where celecoxib is used before the combination of a non-selective NSAID plus a PPI possesses cost advantages for the Quebec provincial drug programme. One-way sensitivity analysis (varying GI and CV event rates, utilities, and cost) generally showed second-line treatment with celecoxib as the dominant strategy compared with third-line treatment with celecoxib.

Conclusion: Although effectiveness of second- and third-line celecoxib use is similar, total cost is lower for second-line. These results suggest that the use of celecoxib before the combination of a non-selective NSAID plus a PPI is relatively cost-effective in the treatment of arthritis pain and support the full benefit listing of celecoxib in Quebec's drug programme.     

Healthcare resource use and costs of privately insured patients who switch,discontinue, or persist on anti-muscarinic therapy for overactive bladder

Objectives:

To compare the healthcare costs of patients with overactive bladder (OAB) who switch vs persist on anti-muscarinic agents (AMs), describe resource use and costs among OAB patients who discontinue AMs, and assess factors associated with persisting vs switching or discontinuing.

Methods:

OAB patients initiating an AM between January 1, 2007 and March 31, 2012 were identified from a claims database of US privately insured beneficiaries (n?≈?16 million) and required to have no AM claims in the 12 months before AM initiation (baseline period). Patients were classified as persisters, switchers, or discontinuers, and assigned a study index date based on their AM use in the 6 months following initiation. Baseline characteristics, resource use, and costs were compared between persisters and the other groups. Resource use and costs in the 1 month before and 6 months after the study index date (for switchers, the date of index AM switching; for persisters, a randomly assigned date to reflect the distribution of the time from AM initiation to switching among switchers) were also compared between persisters and switchers in unadjusted and adjusted analyses. Factors associated with persisting vs switching or discontinuing were assessed.

Results:

After controlling for baseline characteristics and costs, persisters vs switchers had significantly lower all-cause and OAB-related costs in both the month before (all-cause $1222 vs $1759, OAB-related $142 vs $170) and 6 months after the study index date (all-cause $7017 vs $8806, OAB-related $642 vs $797). Factors associated with switching or discontinuing vs persisting included index AM, younger age, and history of UTI.

Conclusion:

A large proportion of OAB patients discontinue or switch AMs shortly after initiation, and switching is associated with higher costs.