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An interesting problem in management of technology and economics of innovation is how to explain the sources of some breakthroughs in research organisations. The present study confronts this problem by analysing the main determinant of the discovery of quasi-periodic materials that has generated a scientific paradigm shift in crystallography. The inductive study shows that radical innovations adopted in research labs, used by high-skilled adopters (called lab-oriented radical innovations; e.g. the Transmission Electron Microscopy), support breakthroughs and enhance discovery processes. This evidence substantiates a theoretical framework, which explains the main relations, characteristics, and properties of lab-oriented radical innovations that improve discovery processes and induce the superior organisational performance in advanced scientific fields. R&D management implications are discussed.  相似文献   

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