The Lognormal Distribution as a Model for Survival Time in Cancer, With an Emphasis on Prognostic Factors

Despite their long history, parametric survival-time models have largely been neglected in the modern biostatistical and medical literature in favour of the Cox proportional hazards model. Here, I present a case for the use of the lognormal distribution in the analysis of survival times of breast and ovarian cancer patients, specifically in modelling the effects of prognostic factors. The lognormal provides a completely specified probability distribution for the observations and a sensible estimate of the variation explained by the model, a quantity that is controversial for the Cox model. I show how imputation of censored observations under the model may be used to inspect the data using familiar graphical and other technques. Results from the Cox and lognormal models are compared and shown apparently to differ to some extent. However, it is hard to judge which model gives the more accurate estimates. It is concluded that provided the lognormal model fits the data adequately, it may be a useful approach to the analysis of censored survival data.     

The representation of the people with disabilities in the internet publishing: North Cyprus example

The representation of people with disabilities in the media is an issue that is not much emphasized. This article studies the representation of people with disabilities in the internet publications, especially in Northern Cyprus. This research, tries to emphasize the way media discuss the issue of disabled people alongside to show how disabled people be presented to the public as a meta in the consumption society and to discuss the discrimination against disabled people. The research focuses on the presentation of the disability as unprotected individuals and the work carried out by the society to sympathize with the individual and in particular on the decoding of the child with disabilities while doing these activities. Media organizations have a widespread belief in their news that they are discriminatory in that they impose disabilities as ‘needy’ individuals. This study discusses how and where barriers are the layout win if on the internet.

     

Labour inclusion of people with disabilities in Spain: the effect of policies and human resource management systems

Abstract

This research answered the question of which elements, linked to HR management, facilitate the labour inclusion of people with disabilities. We analysed the existence of policies in different organizations, and the interaction between these policies and the adaptation of the human resource management systems in order to archive effective labour inclusion. Spanish Human Resource managers answered a questionnaire theoretically based on the Human System Audit model. Results showed that the existence of a strategic plan for the normalization of disability in the work environment effectively leads to high levels of inclusion. This is especially relevant for those organizations that have not adapted the systems of training, professional development and internal communication to people with disabilities. The added value and newness of this research lies in bringing empirical evidence on the role of a strategic plan to normalize disability in the work environment, a policy with an internal- and external-focus, as a diversity strategy roadmap in the framework of an inclusive culture.     

How Do Social Networks Influence the Employment Prospects of People with Disabilities?

We explore the role of social networks used by people with disabilities for finding employment. In addition, we outline obstacles to network building for those with a disability. We contend that this group is often constrained and they underutilize their networks during job searches. Both factors are likely to result in negative employment outcomes and contribute to the employment gap between those with and without a disability. We outline how key network characteristics such as homophily, tie strength, and centrality influence job search outcomes for those with a disability differently than for those without a disability. Furthermore, we propose that although individuals with disabilities develop and rely upon networks that are comprised of close bonds with similar individuals that are either unemployed or underemployed in lower status positions, optimal networks for employment purposes should consist of diverse acquaintances that occupy central positions and higher status jobs within organizations. Finally, we outline propositions to guide future research on this neglected topic and also suggest practical implications.     

Reflections from Employers on the Disabled Workforce: Focus Groups with Healthcare,Hospitality and Retail Administrators

Historically, employment rates for people with disabilities have been low. Despite legislation that prohibits the discrimination of this group in work settings, employers are reluctant to hire people with disabilities. The purpose of this qualitative study was to explore the experiences of employers with workers with disabilities. Three focus groups were conducted with 21 administrators from three business sectors (i.e., healthcare, hospitality, and retail). Content analysis indicated five primary themes: (1) importance of disability employment agencies and disability advocates; (2) persistence of manager bias; (3) lack of promotion opportunities; (4) costs associated with having workers with disabilities; and (5) benefits associated with having workers with disabilities. Implications include the need for intervention studies that address the challenges experienced by individuals with disabilities, particularly during hiring and promoting phases of employment, and educational efforts to inform administrators and managers of the few costs and numerous benefits associated with having workers with disabilities.     

Performance of methods to conduct mediation analysis with time-to-event outcomes

Previous studies have discouraged the use of the Cox proportional hazards (PH) model for traditional mediation analysis as it might provide biased results. Accelerated failure time (AFT) models have been proposed as an alternative for Cox PH models. In addition, the use of the potential outcomes framework has been proposed for mediation models with time-to-event outcomes. The aim of this paper is to investigate the performance of traditional mediation analysis and potential outcomes mediation analysis based on both the Cox PH and the AFT model. This is done by means of a Monte Carlo simulation study and the illustration of the methods using an empirical data set. Both the product-of-coefficients method of the traditional mediation analysis and the potential outcomes framework yield unbiased estimates with respect to their own underlying indirect effect value for simple mediation models with a time-to-event outcome and estimated based on Cox PH or AFT.     

Increasing Employment of People with Disabilities: The Role and Views of Disability Training and Placement Agencies

Many people with disabilities continue being unemployed or underemployed. One way to rectify this situation is through leveraging the services of disability training and placement agencies which can appropriately train candidates with a disability and then connect them with potential employers. Unfortunately, employers profess ignorance about the availability of such services, such service agencies, and continue being wary of employing people with disabilities. In the present article, based on interviews with twelve policy makers in five agencies, we examine services offered by such agencies. Results showed that agencies engage in the following four roles when trying to secure employment for candidates with a disability- the Facilitator, the Trainer, the Marketer, and the Partner. Based on present findings, we note a few broad recommendations for employers with regards formulating their disability policies.     

Development of a voice recognition based system to help physically disabled people use the facebook

Social network sites (SNSs) have become so popular that the number of people joining and actively participating on such sites is increasing on a daily basis. Although there are several SNSs, Facebook is currently the most popular and most commonly used. SNSs have primarily been developed with able-bodied people in mind and as a result of this, people with disabilities find it difficult to join and participate on these sites. Furthermore, this topic has received little attention by researchers around the world. Facebook pages usually consist of text, graphics, and sound where the users navigate through the pages using a mouse. As a step towards addressing this need and finding a possible elegant solution, the authors have developed a voice-activated PC-based system (called NEU-FACE) in the form of an interface to Facebook. With the aid of this system, a person with a physical disability can join and participate in Facebook by giving voice commands to manage the typical Facebook activities.

     

Comparing hazard models for the growth failure of children in Iran

One of the statistical methods deployed in medical sciences to investigate time to event data is the survival analysis. This study, comparing efficiency of some parametric and semiparametric survival models, aims at investigating the effect of demographic and socio-economic factors on the growth failure of children below 2 years of age in Iran. The survival models including exponential, Weibull, log-logistic and log-normal models were compared to proportional hazards and extended Cox models by Akaike Information Criterion and variability of the estimated parameters. Based on the results, the log-normal model is recommended for analyzing the growth failure data of children in Iran. Furthermore, it is suggested that female children, children born to illiterate mothers and children born in larger households receive more attention in terms of growth failure.     

The Measurement and Structural Modeling of the Reasonableness of Workplace Accommodations

The Americans with Disabilities Act of 1990 (ADA) guarantees protection from discrimination for persons with a disability. The ADA requires employers to make reasonable accommodations for persons with physical and mental disabilities unless doing so would produce undue hardship on the organization. Fifteen years after the passage of the ADA, the question as to what is a reasonable accommodation remains controversial, especially for some types of disabilities. In this study, a reasonable accommodation scale is proposed and tested using structural equation modeling in hopes that such a scale will aid the courts and organizations in determining what is reasonable. Individuals’ level of awareness of disability issues is also examined in the model to examine the relationship between awareness and willingness to accommodate. Results indicate acceptable fit of the model to the data and provide support for the proposed scale. Furthermore, the relationship between awareness of disability issues and willingness to accommodate was significant. Implications for research and practice are discussed.     

Thriving of employees with disabilities: The roles of job self‐efficacy,inclusion, and team‐learning climate

With the growing global emphasis on welfare‐to‐work policies, an increasing number of people with disabilities (PWD) have entered the workforce. However, studies on PWD have focused primarily on company practices to accommodate PWD, with a limited understanding of factors affecting psychological integration of PWD into the workplace. This scarcity in research makes it difficult for managers to utilize the full work potential of PWD. To fill this research gap, the current study focuses on the job self‐efficacy of PWD and investigates how employee disability interacts with inclusion and team‐learning climate to affect job self‐efficacy, and in turn thriving at work. Using a sample of 485 employees in 114 teams, surveys found job self‐efficacy was a key intervening mechanism linking employee disability to thriving at work. These results suggest high workplace inclusion can buffer potential negative effects of disability at the individual level, strengthened further by a high team‐learning climate. The data supported a three‐way cross‐level interaction effect of disability, inclusion, and team‐learning climate on the thriving of employees with disabilities, through job self‐efficacy. Our results demonstrate the importance of inclusion and team‐learning climate to foster employee thriving in a diverse workforce.     

On the treatment of persons with disabilities in organizations: A review and research agenda

Human resource practitioners play a crucial role in promoting equitable treatment of persons with disabilities, and practitioner's decisions should be guided by solid evidence‐based research. We offer a systematic review of the empirical research on the treatment of persons with disabilities in organizations, using Stone and Colella's seminal theoretical model of the factors influencing the treatment of persons with disabilities in work organizations, to ask: What does the available research reveal about workplace treatment of persons with disabilities, and what remains understudied? Our review of 88 empirical studies from management, rehabilitation, psychology, and sociology research highlights seven gaps and limitations in extant research: (a) implicit definitions of workplace treatment; (b) neglect of national context variation; (c) missing differentiation between disability populations; (d) overreliance on available data sets; (e) predominance of single‐source, cross‐sectional data; (f) neglect of individual differences and identities in the presence of disability; and (g) lack of specificity on underlying stigma processes. To support the development of more inclusive workplaces, we recommend increased research collaborations between human resource researchers and practitioners on the study of specific disabilities and contexts, and efforts to define and expand notions of treatment to capture more nuanced outcomes.     

Age and Assessments of Disability Accommodation Request Normative Appropriateness

In the United States, the labor force continues to age. As age increases, so does the likeliness of needing disability accommodation. Prior research indicates that people with disabilities often do not request needed accommodations when they assess that others at work would perceive a request as normatively inappropriate. Little, however, is currently known about the impact of age on these assessments. In this study, we integrate prior research on age, disability, social identity, and climate to propose and then test a model of the relationship between requesters’ age and their normative assessments using survey data from 242 people who became hearing impaired prior to entering the workforce. As hypothesized, requester age was negatively associated with normative appropriateness assessment favorability. Moreover, this negative influence was stronger in for‐profit organizational contexts and in workgroup contexts in which the requester lacked a coworker with a disability. Having a coworker with a similar disability also partially mediated the moderating effect of organization type on the association between age and normative appropriateness assessment favorability. Implications for research and practice are discussed. © 2015 Wiley Periodicals, Inc.     

Mobile device based smart medication reminder for older people with disabilities

With the latest research in the fields of medicine and pharmaceutical sciences, an increasing number of drugs are being invented to cure many fatal diseases and this has enabled people to live healthier and longer. Consequently, the rate of medication usage is increasing, particularly among the elderly. It is important that the medication prescribed by doctors is taken at the correct times of the day and in the correct dosages. This seems to be a significant problem encountered by older people with disabilities. As a result of forgetfulness or other problems, many older patients either do not take the correct medicines or the correct dosage at the appropriate times and this reduces the benefits of treatments and increases both healthcare costs and the mortality rates. In order to find a solution to this problem, a mobile phone and Cloud-based smart application has been developed to improve patient adherence, particularly for older people with disabilities. The novelty of the developed application is the use of a Cloud service to provide two-way communication in the form of feedback between the older patients with disabilities and the doctors so that the medication adherence of the patients can be monitored. Mobile application developers should find the developed mobile phone based medication reminder application for older people with disabilities a useful example application, and it should help them in developing other mobile applications for older people with disabilities.

     

Functioning, Capability and Freedom: A Framework for Understanding Workplace Disabilities

Work-related disability issues have been central in many of the U.S. public policy debates since the late 1970s and early 1980s. Although there is a robust business, legal, and public policy literature dealing with such issues philosophical analyses are not common. Accordingly, the paper examines, from a broadly philosophical perspective, some of the issues associated with restricted workplace employment opportunities due to the presence of one or more real or perceived disabilities. Following a review of the concept of disability, the paper examines disabilities and impairments using the concepts of functionings and capabilities developed by Amartya Sen and Martha Nussbaum. The paper then connects the capabilities approach to disabilities with the concepts of negative and positive freedom developed by Isaiah Berlin. The paper concludes by suggesting how to address employment and workplace discriminations of disabled people.     

Variance components models for survival data

Extensions of the Cox proportional hazards model for survival data are studied where allowance is made for unobserved heterogeneity and for correlation between the life times of several individuals. The extended models are frailty models inspired by Y ashin et al. (1995). Estimation is carried out using the EM algorithm. Inference is discussed and potential applications are outlined, in particular to statistical research in human genetics using twin data or adoption data, aimed at separating the effects of genetic and environmental factors on mortality.     

Socialization of people with disabilities in the workplace

Socialization has crucial outcomes for both the employee and the employer. Through an exploratory qualitative study conducted in India, we examined how people with disabilities (PWD) viewed various aspects of their socialization process. Specifically, we looked at the role of coworkers, supervisors, organizational practices, and employee proactive behaviors in influencing organizational integration. We found that integration was most influenced by coworkers and supervisors. Organizational practices and employee proactive behaviors were less important. Respondent gender and tenure also influenced certain findings. Specifically, PWD with less tenure sought and accepted more help from coworkers and supervisors. Further, more men with disabilities than women with disabilities indicated that they were proactive in terms of obtaining training to make themselves employable, and more men with disabilities indicated that having coworkers with a disability helped them during socialization. We discuss both theoretical and practical implications as well as future research directions based on our findings. © 2011 Wiley Periodicals, Inc.     

Analysis of failure time using threshold regression with semi‐parametric varying coefficients

Many new statistical models may enjoy better interpretability and numerical stability than traditional models in survival data analysis. Specifically, the threshold regression (TR) technique based on the inverse Gaussian distribution is a useful alternative to the Cox proportional hazards model to analyse lifetime data. In this article we consider a semi‐parametric modelling approach for TR and contribute implementational and theoretical details for model fitting and statistical inferences. Extensive simulations are carried out to examine the finite sample performance of the parametric and non‐parametric estimates. A real example is analysed to illustrate our methods, along with a careful diagnosis of model assumptions.     

Accommodating Employees With and Without Disabilities

Efforts to recruit and retain employees with disabilities are often tempered by employers’ concerns over potential workplace accommodation costs. This study reports on accommodations requested and granted in intensive case studies of eight companies, based on more than 5,000 employee and manager surveys, and interviews and focus groups with 128 managers and employees with disabilities. Two unique contributions are that we analyze accommodations for employees without disabilities as well as for those with disabilities, and compare perspectives on accommodation costs and benefits among employees, their coworkers, and their managers. We find people with disabilities are more likely than those without disabilities to request accommodations, but the types of accommodations requested and the reported costs and benefits are similar for disability and non‐disability accommodations. In particular, fears of high accommodation costs and negative reactions of coworkers are not realized; all groups tend to report generally positive coworker reactions. Multilevel models indicate granting accommodations has positive spillover effects on attitudes of coworkers, as well as a positive effect on attitudes of requesting employees, but only when coworkers are supportive. Consistent with recent theorizing and other studies, our results suggest the benefits from a corporate culture of flexibility and attention to the individualized needs of employees. © 2014 Wiley Periodicals, Inc.     

Perspectives on Disability Disclosure: The Importance of Employer Practices and Workplace Climate

Disclosing a disability to a potential or current employer is a very personal decision, with potentially far-reaching consequences for both the employer and employee. Disability disclosure can assure that employees receive appropriate workplace accommodations, and can help employers respond more effectively to diversity and inclusion initiatives aimed at increasing the hiring and retention of individuals with disabilities. However, disclosure may also result in negative employment consequences for employees, such as lowered supervisor expectations, isolation from co-workers, and increased likelihood of termination. Given demographic trends related to disability in the labor force and recent initiatives to increase the employment of individuals with disabilities, it is increasingly important that employers create an environment that encourages disclosure and reduces the likelihood of negative consequences for employees and applicants who disclose their disabilities. This paper presents the findings of a survey of individuals with disabilities focused on identifying and better understanding the factors that influence the disclosure decision. Results highlight the barriers and facilitators that influence individuals’ decision to disclose and the important role that employers, managers, and workplace climate play in the decision. Implications for employer policy and practice are also discussed.