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1.
This paper presents a model of predation based on reputational differences between the entrant and an incumbent. While the incumbent has an established reputation in the debt market, the entrantss quality is not yet known in the debt market. We show that the incumbent may have incentives to prey in order to interfere with the reputation acquisition of the entrant.Received: June 2002 , Accepted: December 2002, JEL Classification: C72, D82, G3, L1I am grateful to one anonymous referee for very valuable comments. In addition, for helpful comments on previous versions of this paper, I thank Drew Fudenberg, Jean Tirole, António Pires, Soumodip Sarkar, and seminar participants at M.I.T., Boston University and Western Ontario University.  相似文献   

2.

This paper examines the relationship between India’s quarterly overall GDP, manufacturing GDP and services GDP and the corresponding monthly data on overall manufacturing and services PMI for the period January 2006 to July 2014. The objective is to see if the two overall PMIs are related to the level and quarterly growth rate of overall GDP and its chosen components. Considering the quarterly time series nature of the data set, the HEGY equation of Hylleberg et al. (J Econom 44:215–238, 1990) extended by adding the PMI variables as exogenous regressors is used as the regression mode to relate a GDP level/growth rate variable to the two overall PMI variables. The results show that the three GDP level variables, but none of the GDP growth rate variables, have significant positive correlation with services PMI, but not with manufacturing PMI. Finally, the marginal effect of services PMI on manufacturing GDP level is found to be the largest, followed by that for overall GDP level and services GDP level.

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3.
This paper is based on a recent nonparametric forecasting approach by Sugihara, Grenfell and May (1990) to improve the short term prediction of nonlinear chaotic processes. The idea underlying their forecasting algorithm is as follows: For a nonlinear low-dimensional process, a state space reconstruction of the observed time series exhibits spatial correlation, which can be exploited to improveshort term forecasts by means of locally linear approximations. Still, the important question of evaluating the forecast perfomance is very much an open one, if the researcher is confronted with data that are additionally disturbed by stochastic noise. To account for this problem, a simple nonparametric test to accompany the algorithm is suggested here. To demonstrate its practical use, the methodology is applied to observed price series from commodity markets. It can be shown that the short term predictability of the best fitting linear model can be improved upon significantly by this method.  相似文献   

4.
Aims: To develop a budget impact model (BIM) for estimating the financial impact of formulary adoption and uptake of calcipotriene and betamethasone dipropionate (C/BD) foam (0.005%/0.064%) on the costs of biologics for treating moderate-to-severe psoriasis vulgaris in a hypothetical US healthcare plan with 1 million members.

Methods: This BIM incorporated epidemiologic data, market uptake assumptions, and drug utilization costs, simulating the treatment mix for patients who are candidates for biologics before (Scenario #1) and after (Scenario #2) the introduction of C/BD foam. Predicted outcomes were expressed in terms of the annual cost of treatment (COT) and the COT per member per month (PMPM).

Results: At year 1, C/BD foam had the lowest per-patient cost ($9,913) necessary to achieve a Psoriasis Area and Severity Index (PASI)-75 response compared with etanercept ($73,773), adalimumab ($92,871), infliximab ($34,048), ustekinumab ($83,975), secukinumab ($113,858), apremilast ($47,960), and ixekizumab ($62,707). Following addition of C/BD foam to the formulary, the annual COT for moderate-to-severe psoriasis would decrease by $36,112,572 (17.91%, from $201,621,219 to $165,508,647). The COT PMPM is expected to decrease by $3.00 (17.86%, from $16.80 to $13.80).

Limitations: Drug costs were based on Medi-Span reference pricing (January 21, 2016); differences in treatment costs for drug administration, laboratory monitoring, or adverse events were not accounted for. Potentially confounding were the definition of “moderate-to-severe” and the heterogeneous efficacy data. The per-patient cost for PASI-75 response at year 1 was estimated from short-term efficacy data for C/BD foam and apremilast only.

Conclusions: The introduction of C/BD foam is expected to decrease the annual COT for moderate-to-severe psoriasis treatable with biologics by $36,112,572 for a hypothetical US healthcare plan with 1 million plan members, and to lower the COT PMPM by $3.00.  相似文献   


5.
Summary This paper views uncertainty and economic fluctuations as being primarily endogenous and internally propagated phenomena. The most important Endogenous Uncertainty examined in this paper is price uncertainty which arises when agents do not have structural knowledge and are complelled to make decisions on the basis of their beliefs. We assume that agents adopt Rational Beliefs as in Kurz [1994a]. The trading of endogenous uncertainty is accomplished by using Price Contingent Contracts (PCC) rather than the Arrow-Debreu state contingent contracts. The paper provides a full construction of the price state space which requires the expansion of the exogenous state space to include the state of beliefs. This construction is central to the analysis of equilibrium with endogenous uncertainty and the paper provides an existence theorem for a Rational Belief Equilibrium with PCC. It shows how the PCC completes the markets for trading endogenous uncertainty and lead to an allocation which is Pareto optimal. This paper also demonstrates that endogenous uncertainty is generically present in this new equilibrium.This research was supported in part by the Fondazione Eni Enrico Mattei of Milan, Italy, and by the National Science Council of Taiwan. The authors thank Carsten K. Nielsen for valuable suggestions.  相似文献   

6.
Summary. This paper explores an old solution for bankruptcy problems, described by Ibn Ezra in the XII century. Particularly, we introduce a new way of extending the Ibn Ezras proposal, the Generalized Ibn Ezra solution, by imposing that the general distribution principle from which it is inspired remains fixed. In this context, we follow the interpretation of bankruptcy problems in terms of TU games given in ONeill (1982), and propose the analysis of the Transition Game associated to bankruptcy problems to provide a characterization for the Generalized Ibn Ezra solution.Received: 14 October 2003, Revised: 26 May 2004, JEL Classification Numbers: C71, D63, D71. Correspondence to: José Alcalde: alasur@merlin.fae.ua.esWe are grateful to Carmen Herrero, Juan de Dios Moreno, William Thomson and an anonymous referee for helpful comments. Authors work is partially supported by the Institut Valenciá dInvestigacions Económiques. Alcalde and Silva acknowledge support by FEDER and the Spanish Ministerio de Educación y Cultura under project BEC 2001-0535. Marco acknowledges support by the Fundación Séneca, and the Spanish Ministerio de Educación y Cultura under projects SEC2000-0838 and BEC 2001-0781.  相似文献   

7.
Summary. We present a new class of rules named augmented serial rules for the provision of an excludable public good. First, we characterize this class by the four axioms of strategy-proofness, envy-freeness, access independence, and nonbossiness. Second, we identify two important subclasses by imposing an additional axiom: (i) anonymous augmented serial rules by anonymity, and (ii) Moulins serial rule by individual rationality.Received: 31 December 2002, Revised: 9 June 2004, JEL Classification Numbers: D71, D82, H41.This paper is a substantial revision of Serial cost sharing with simple games. I would like to thank Hervé Moulin, Yoshikatsu Tatamitani, an associate editor, and three anonymous referees for helpful suggestions and detailed comments. This research was partially supported by the Ministry of Education, Culture, Sports, Science, and Technology in Japan (Grant-in-Aid for 21st Century COE Program Microstructure and Mechanism Design in Financial Markets).  相似文献   

8.

The study examines the Fisher’s hypothesis using India’s macroeconomic data with main objective of ascertaining the empirical relationship between nominal interest rate and expected inflation. The study collected monthly time series data on interest rate (lending rate) and CPI growth rate (inflation) from Reserve Bank of India’s database spanning from 1990M01 to 2015M03. To achieve the objective, the study first examined the univariate stochastic properties of the series using test that assumed the presence of structural: Zivot and Andrews (J Bus Econ Stat 10(3):251–270, 1992) and Perron (J Econ 80:355–385, 1997) on one hand and those that assumed no break: Elliot et al. (Econometrica 64:813–836, 1996) and Kwiatkowski et al. (J Econom 54:159–178, 1992) on the other hand. The result for the univariate stochastic properties revealed that inflation is level stationary whereas lending rate is differenced stationary. This finding is consistent with the two tests considered as mentioned above. To examined the Fisher’s effect, given the result of the univariate stochastic properties, the study checked the multivariate counterpart using test that assumed break; Gregory and Hensen (J Econom 70:99–126, 1996) and the one that assumed no break; Pesaran et al. (J Appl Econom 16:289–326, 2001). The result reveals the absence of long run equilibrium between nominal interest rate and inflation for the full and sub-samples which is against Fisher’s proposition. This finding can be attributed to the following reasons: firstly, the conduct of monetary policy by RBI is passive; that is, the policy rate response less than proportionate to change in inflation. Secondly, the presence of distortion in the interest rate pass-through channel makes the sign, speed and magnitude of monetary policy uncertain and finally, the dominant of informal financial sector in India that makes short term policy rate ineffective monetary policy instrument. Therefore the study concludes that the conduct of monetary policy is responsible for the rejection of Fisher’s hypothesis in India.

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9.
Summary This note reconsiders the well-known model of strategic bequest/ altruistic growth, but with stochastic production satisfying a strong convexity condition: The probability that the next stock exceeds any given level is concave in investment. Existence of a Markov-stationary equilibrium consumption schedule, which is continuous and with all slopes in [0,1], is established. Under smooth data and interiority assumptions, this schedule is differentiable, and marginal consumption is in (0,1). This property allows for a rigorous and straightforward treatment of the equilibrium characterization problem.The author is grateful to Wolfgang Leininger for helpful discussions on the subject of this paper. This research work was carried out while the author was visiting C.O.R.E., Belgium and the University of Dortmund, Germany. The author wishes to thank both institutions for providing a great work environment as well as financial support from the projects Markets as Games and Marktstruktut und Gesamtwirtschaftliche Entwicklung, respectively.  相似文献   

10.
Objective: To evaluate cost-effectiveness of brentuximab vedotin in patients with relapsed/refractory Hodgkin lymphoma who have received autologous stem cell transplantation, from a Scottish healthcare payer perspective.

Methods: A Microsoft Excel-based partitioned survival model comprising three health states (progression-free survival [PFS], post-progression survival, and death) was developed. Relevant comparators were chemotherapy with or without radiotherapy (C/R) and C/R with intent to allogeneic hematopoietic stem cell transplantation (alloSCT). Data were obtained from the pivotal phase II single-arm trial in 102 patients (SG035-0003; NCT00848926), a systematic literature review and clinical expert opinions (where empirical evidence was unavailable). PFS and overall survival for brentuximab vedotin were estimated using 5-year follow-up data from SG035-0003, and extrapolated using event rates observed for comparator treatments from published survival data. Resource use included drug acquisition and administration; alloSCT; treatment of adverse events; and long-term follow-up. Deterministic and probabilistic sensitivity analyses were conducted to evaluate the impact of uncertainty.

Results: In the base case, the incremental cost-effectiveness ratio (ICER) for brentuximab vedotin was £38,769 per quality-adjusted life year (QALY) vs C/R, whereas C/R with intent to alloSCT was dominated by brentuximab vedotin. ICERs for brentuximab vedotin generated by the deterministic sensitivity analysis ranged between £32,000–£54,000 per QALY. Including productivity benefits reduced the ICER to £28,881 per QALY.

Limitations: Limitations include lack of comparative data from this single arm study and the heterogeneous population. Inconsistent baseline characteristic reporting across studies prevented complete assessment of heterogeneity and the extent of potential bias in clinical and cost-effectiveness estimates.

Conclusions: Although the base case ICER is above the threshold usually applied in Scotland, it is relatively low compared with other orphan drugs, and lower than the ICER generated using a previous data cut of SG035-0003 that informed a positive recommendation from the Scottish Medicines Consortium, under its decision-making framework for assessment of ultra-orphan medicines.  相似文献   


11.

The USD-INR currency pair has often been in the news for its excess volatility. This study examines the veracity of this belief by using the extreme value estimator proposed by Rogers and Satchell (Ann Appl Prob 1(4):504–512, 1991) and the VRatio proposed by Maheswaran et al. (J Emerg Mark Finance 10(2):175–196, 2011). The volatility in the USD-INR exchange rate is determined for the period beginning January 2009 and ending June 2015. The volatility of the GBP-INR and EUR-INR currency pairs is also determined for making comparisons. The results show that the EUR-INR and the GBP-INR currency pairs exhibit excess volatility, but not the USD-INR. This result runs counter to the commonly held view. This study also examines the volatility of the three currency pairs using the multiple-days’ time windows for better approximation of Brownian motion while embedding the jumps in the daily opening prices. There is no evidence to support the existence of excess volatility in the USD-INR.

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12.
Throughout the nineties, a number of tender offers occurred in the Portuguese market. This article employs event study methodology to investigate their effects on the involved firms shareholders. On average, these operations increased the market value of the involved firms by 2% to 3%. However, target shareholders appropriated most of this gain, earning 18% over their firms previous value, whereas bidder shareholders seem to have gained nothing. These averages bent in bidders shareholders favour, however, when bidders held significant positions in the targets capital before the bid.Received: December 2002, Accepted: September 2003, JEL Classification: G14, G34This paper corresponds to a revised version of chapter 6 of my PhD dissertation. I have greatly benefited from comments by my supervisors José Manuel Amado da Silva and Victor Mendes dos Santos, Pedro Pita Barros, participants in the 9o Encontro Nacional de Economia Industrial and in an internal seminar at the Faculdade de Economia e Gestão, and two anonymous referees. The responsibility for any remaining errors is, of course, exclusively mine. CMVM and BDP have kindly provided the data used. Grant PRAXIS/PCSH/C/CEG/30/96 partially supported this research.  相似文献   

13.
Aims: Data highlighting the cost drivers for non-valvular atrial fibrillation (NVAF) patients in terms of vitamin K antagonist (VKA) treatment and monitoring are lacking in France. This study aimed to evaluate the real-life daily cost of VKA treatment in 2013, in French patients suffering from NVAF.

Methods: This longitudinal observational study was performed using the EGB (Echantillon Généraliste des Bénéficiaires) database, a random sample of the French national insurance (NHI) database, which covers 80% of the population. All adult patients whose first NVAF anticoagulant treatment in 2013 was a VKA were analyzed. Costs were calculated for the duration of follow-up and then divided by the number of days of therapy. The analysis was performed both from the French NHI perspective (amount reimbursed by the NHI) and from a collective perspective.

Results: In this study, 3,254 NVAF patients treated with VKA in 2013 were included, and this sample comprised 52.6% males. The mean daily cost of VKA treatment was €1.13 (±1.18) according to the collective perspective (89.4% of this cost was associated to INR measurement) and €1.05 (±1.16) according to the NHI perspective.

Limitations: As diagnoses associated with procedures are not available in the EGB database, proxies were used, and an algorithm was created to define the AF population.

Conclusions: This analysis is the first to consider an exhaustive spectrum of the costs of VKA treatment in France using EGB data. VKA medication requires exhaustive follow-up, and, thus, associated costs are important. The results of the present study confirmed this close follow-up for VKA patients, making the cost of treatment by VKA nearly 10-times more expensive than the cost of medication itself.  相似文献   


14.
Summary. This paper studies repeated games with imperfect private monitoring when there exists a third-party mediator who coordinates play by giving non-binding instructions to players on which action to take and by collecting their private information. The paper presents a Nash-threat folk theorem for a communication equilibrium based on such mediation when monitoring is jointly -perfect in the sense that every player is almost perfectly monitored collectively by other players.JEL Classification Numbers: C72, D82.I am very grateful to Mark Armstrong, V. Bhaskar, and Michihiro Kandori for helpful comments. Part of this research was conducted while I was visiting the University College London. Their hospitality is gratefully acknowledged.  相似文献   

15.
The evolution of conventions under incomplete information   总被引:3,自引:0,他引:3  
Summary. We formulate an evolutionary learning process with trembles for static games of incomplete information. For many games, if the amount of trembling is small, play will be in accordance with the games (strict) Bayesian equilibria most of the time. This supports the notion of Bayesian equilibrium. Often the process will select a specific equilibrium. We study an extension to incomplete information of the prototype conflict known as Chicken and find that the equilibrium selection by evolutionary learning may well be in favor of inefficient Bayesian equilibria where some types of players fail to coordinate.Received: 17 March 2003, Revised: 3 December 2003, JEL Classification Numbers: C72.  相似文献   

16.
Summary. We provide conditions under which the heterogenous, deterministic preferences of consumers in a pure exchange economy can be identified from the equilibrium manifold of the economy. We extend those conditions to consider exchange economies, with two commodities, where consumers preferences are random. For the latter, we provide conditions under which consumers heterogenous random preferences can be identified from the joint distribution of equilibrium prices and endowments. The results can be applied to infer consumers preferences when their demands are unobservable.Received: 8 May 2003, Revised: 14 September 2004, JEL Classification Numbers: D12, D51.I am very grateful to an anonymous referee, Donald Brown, and Daniel McFadden for their detailed comments and insightful suggestions. Section 2 of this paper is joint work with Donald J. Brown; it is included here for publication with his permission. Those results were presented at the 1990 Workshop on Mathematical Economics at the University of Bonn, the 1992 SITE Workshop on Empirical Implications of General Equilibrium Models at Stanford University, and, more recently, at the June 2000 Conference in Honor of Rolf Mantel, in Buenos Aires, Argentina. The comments of the participants at those conferences and workshops are much appreciated. The research presented in this paper was supported by NSF Grants SES-8900291, SBR-9410182, and SES-0241858. This paper is dedicated to Marcel K. Richter, who has inspired much of my research.  相似文献   

17.
In this paper we explore the notion that players are decent in the sense that their choices are bounded by certain unwritten social rules. We apply this idea to problems of Bankruptcy and Implementation.JEL Classification: D78, D63The authors wish to express their gratitude for comments and suggestions to N. Baigent, S. Baliga, V. Bashkar, C. Beviá, S. Chattopadhayay, G. Charness, M. Maschler, C. Matutes, P. McAfee, I. Ortuño-Ortín, A. Rangel, J. Roemer, J. Schummer, T. Sjöström, W. Thomson, the participants in seminars in Hakone (Japan), Harvard, Queens University, Rochester, Studienzentrum at Gergenzee (Switzerland), two anonymous referees and an associate editor. The usual caveat applies. This research has been partially supported by grants BEC2002-02194, BEC2001-0535, and GV 01-371. This paper is dedicated to Bob Aumann, from whom we have learned so much.  相似文献   

18.
This paper estimates a VAR including labor productivity, real wage and unemployment rate, to identify the dynamic effects of technology, demand, and mark-up shocks, respectively, on the Italian labor market. Identification is achieved by imposing recursive restrictions on the matrix of long run multipliers. Our results show that both mark up and aggregate demand shocks permanently reduce the unemployment rate. Finally, technology shocks do not significantly affect the unemployment rate in the long run. These findings convey important policy implications: expansionary aggregate demand and deregulation policies reducing the mark up permanently decrease the Italian unemployment rate.Jel classification: C32, E32, J29This paper has been produced as part of a CEPR Research Network on New Approaches to the Study of Economic Fluctuations. We would like to thank Marcello DAmato, Mario Forni, Marco Lippi and Antonio Ribba for useful comments. We are also grateful to Bernd Sussmuth for pointing out to us several significant improvements to the paper.First version received: November 2001/Final version received: October 2002  相似文献   

19.
The Edgeworth-Sargan density has been shown capable of capturing empirical regularities of financial data (thick tails and asymmetries). When compared to other densities used in applied finance, it has the advantage of its analytical simplicity, and the ability to improve data fits by adding more parameters in a natural way. This paper develops an explicit form for the multivariate Edgeworth-Sargan density and compare its performance to the multivariate Students t. The comparison is carried out with daily financial observations, spanning 25 years of data for several financial variables that include stock markets indices and interest and exchange rates for several countries.JEL Classification: C12, G1The author acknowledges Prof. Ignacio Mauleón, PhD supervisor of the dissertation this article is based on, and also to Esther del Brío, Helen Jones and two anonymous referees for their helpful and constructive comments. This paper is financed by the C.I.C.Y.T. under project SEC98-1112 and the J.C.Y.L. under project SA29/99. Responsibility for the contents, as well as possible deficiencies, remains solely with the author.  相似文献   

20.
Bounded rationality in laboratory bargaining with asymmetric information   总被引:2,自引:2,他引:0  
Summary. This paper reports an experiment on two-player sequential bargaining with asymmetric information that features some forces present in multi-round monopoly pricing environments. Buyer-seller pairs play a series of bargaining games that last for either one or two rounds of offers. The treatment variable is the probability of continuing into a second round. Equilibrium predictions do a poor job of explaining levels of prices and treatment effects. As an alternative to the conventional equilibrium model, we consider models that allow for bounded rationality of subjects. The quantal response equilibrium model captures some of the important features of the results.Received: 30 April 2003, Revised: 10 December 2003, JEL Classification Numbers: C78, D82, D42, C91. Correspondence to: Timothy N. CasonThis research was funded in part by the National Science Foundation (SBR-9809110). The experiments were run at the Economic Science Laboratory of the University of Arizona and the Krannert Laboratory for Experimental Economic Research at Purdue University, using the z-Tree software developed at the Institute for Empirical Research at the University of Zurich (Fischbacher [8]). David Cooper, Rachel Croson, Charles Noussair, an anonymous referee, and conference participants at the Economic Science Association and the Society for the Advancement of Economic Theory meetings provided helpful comments. Timothy ONeill Dang, Thomas Wilkening and Marikah Mancini provided expert research assistance.  相似文献   

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