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1.
Response‐adaptive designs are being used increasingly in applications, and this is especially so in early phase clinical trials. This paper reviews a particular class of response‐adaptive designs that have the property of picking the superior treatment with probability tending to one. This is a desirable property from an ethical point of view in clinical trials. The model underlying such designs is a randomly reinforced urn. This paper provides an overview of results for these designs, starting from the early paper of Durham and Yu (1990) until the recent work by Flournoy, May, Moler and Plo (2010).  相似文献   

2.
Current economic theory typically assumes that all the macroeconomic variables belonging to a given economy are driven by a small number of structural shocks. As recently argued, apart from negligible cases, the structural shocks can be recovered if the information set contains current and past values of a large, potentially infinite, set of macroeconomic variables. However, the usual practice of estimating small size causal Vector AutoRegressions can be extremely misleading as in many cases such models could fully recover the structural shocks only if future values of the few variables considered were observable. In other words, the structural shocks may be non‐fundamental with respect to the small dimensional vector used in current macroeconomic practice. By reviewing a recent strand of econometric literature, we show that, as a solution, econometricians should enlarge the space of observations, and thus consider models able to handle very large panels of related time series. Among several alternatives, we review dynamic factor models together with their economic interpretation, and we show how non‐fundamentalness is non‐generic in this framework. Finally, using a factor model, we provide new empirical evidence on the effect of technology shocks on labour productivity and hours worked.  相似文献   

3.
We consider kernel density estimation for univariate distributions. The question of interest is as follows: given that the data analyst has some background knowledge on the modality of the data (for instance, ‘data of this type are usually bimodal’), what is the adequate bandwidth to choose? We answer this question by extending Silverman's idea of ‘normal‐reference’ to that of ‘reference to a Gaussian mixture’. The concept is illustrated in the light of real data examples.  相似文献   

4.
Although a traditional project model is clearly useful for laying out the patterns of relationships surrounding a project, it does not provide the temporally embedded accounts that enable us to understand how organizational learning takes place. The process thinking perspective offers a means to solving this problem. This article provides an analysis of how different processes interact dynamically in order to benefit project‐based companies' organizational learning. Two findings from this study are: (1) organizational learning is a dynamic concept that emphasizes the continually changing nature of a project‐based company and (2) sensemaking and negotiation of meaning are ongoing processes in project‐based companies.  相似文献   

5.
A rich theory of production and analysis of productive efficiency has developed since the pioneering work by Tjalling C. Koopmans and Gerard Debreu. Michael J. Farrell published the first empirical study, and it appeared in a statistical journal (Journal of the Royal Statistical Society), even though the article provided no statistical theory. The literature in econometrics, management sciences, operations research and mathematical statistics has since been enriched by hundreds of papers trying to develop or implement new tools for analysing productivity and efficiency of firms. Both parametric and non‐parametric approaches have been proposed. The mathematical challenge is to derive estimators of production, cost, revenue or profit frontiers, which represent, in the case of production frontiers, the optimal loci of combinations of inputs (like labour, energy and capital) and outputs (the products or services produced by the firms). Optimality is defined in terms of various economic considerations. Then the efficiency of a particular unit is measured by its distance to the estimated frontier. The statistical problem can be viewed as the problem of estimating the support of a multivariate random variable, subject to some shape constraints, in multiple dimensions. These techniques are applied in thousands of papers in the economic and business literature. This ‘guided tour’ reviews the development of various non‐parametric approaches since the early work of Farrell. Remaining challenges and open issues in this challenging arena are also described. © 2014 The Authors. International Statistical Review © 2014 International Statistical Institute  相似文献   

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