Connecting life science entrepreneurs with resources and expertise: the role of iungens brokerage in life science innovation

Life science innovation demands detailed expertise at each stage of the development of a commercial product. Besides a perceived shortage of venture capital, venturing life science companies face the challenge of limited access to qualified expertise in regulatory affairs and commercialisation. Examining a bio hub initiative at a major pharmaceutical company, a form of in-house incubator wherein life science companies can both take advantage of laboratory facilities and the stock of expertise of the hosting company, it is argued that such initiatives support the life science innovation field. Taking on an iungens brokerage role, the hosting company effectively connects previously separated actors, thus lowering the transaction costs incurred when accessing qualified scientific, regulatory, and commercial know-how, which are all of great value to life science companies during the venturing phase. The iungens brokerage role thus represents a highly valuable position in the field of life science innovation.     

Financial innovation,economic growth,and the consequences of macroprudential policies

We leverage a ‘catch-all’ measure of financial innovation—research and development spending in the financial sector—to assess the net relationship between financial innovation and economic growth and evaluate the influence of macroprudential policy on this relationship. Using a panel of 23 countries over the period of 1996–2014, our results demonstrate a net-positive relationship between financial innovation and gross capital formation. We find no evidence of a net-negative impact of financial innovation on economic growth, challenging the popular and political stigma surrounding financial innovation. We also find little robust evidence of macroprudential policy influencing the relationship between financial innovation and economic growth. Our results support a functional approach to the regulation of financial innovation, which improves the intermediation process, leading to increased capital formation.     

Regional innovation environment and innovation efficiency: the Chinese case

The main goal of this paper is to analyse the connotation of ‘regional innovation environment’ and explore the relationships between the regional innovation environmental components and innovation efficiency (IE). Three regional environmental factors were extracted, namely, economic infrastructure (EI), the quality and structure of innovators (QSI) and regional openness (RO). The relationships between the regional innovation environmental components and innovation efficiency present a chain structure as RO–EI–QSI–IE. Only the QSI component affects IE directly, and all of the effects are positive. Based on these results, the characteristics of Chinese regional innovation systems were analysed, and the implications on science & technology policy were discussed.     

Organisational form and the economic impacts of innovation: the case of patent grant announcements

This study investigates the impact of corporate diversification on the value creation of patent grants. We find that focussed firms experience significantly greater market reactions to patent announcements than diversified firms. Diversification into related industries has little effect on the wealth gains of granted patents, while diversification into unrelated industries significantly reduces the wealth gains. We further find that post-announcement operating performance is significantly associated with the degree of diversification. Overall, our findings suggest that the selection of diversification as a firm's organisational structure has a negative influence on the value creation of innovation, and this influence is exacerbated when this diversification involves unrelated industries.     

Tax-spending policies and economic growth: Theoretical predictions and evidence from the OECD

We present an endogenous growth model to study the growth effects of the composition of government expenditure and the associated tax burden. When we use data from a set of 23 OECD countries during 1970–2000, our econometric results support the predictions of the theory. The share of productive government expenditure is associated with higher growth, and this result is more robust when we use effective average tax rates and statutory tax rates as measures of the tax burden. With respect to the tax burden, different tax rates have different growth effects.     

基于多中心治理理论的农业科技创新

我国提出的建设社会主义新农村,实现城乡统筹发展是一项长期而艰巨的社会系统性工程,以科技创新作为重要推动的手段,将成为农业发展的根本出路。但农业科技创新也需要有新的治理模式,传统的以城市政府为中心的单中心治理模式由于其内在的制度性缺陷严重影响了科技长入经济的进程。城市、农村以及各级政府、市场和城乡社会三维框架下的多中心治理模式打破了单中心制度安排中最高权威单一性的权力格局,由多个相对独立的发展主体构成的治理网络承担起了农业科技创新区域内的管理和服务职责,并显示出一定的优势。应通过借鉴多中心治理理论中的合理内核,通过构建一种政府引导、市场运作、农民为主、社会参与的＂多元共治＂模式,来推动农业科技创新的顺利进行。     

The relationship between business diversification and productivity: considering the impact of process innovation at different corporate life cycles

This paper investigates the link between a firm's process innovation (PI) and its segment productivity at different life cycles. The results show that business diversification is negatively associated with a firm's productivity, and further reveal that a firm's PI moderates the above relationship. In addition, the corporate life cycle literature builds blocks for this study to explain that the involvement of administrative costs varies across life cycles when diversified firms get mature and bigger. Our empirical evidence indicates that the potential costs of a complex organisational structure contingent on business diversification at a firm's mature life cycle could be alleviated by the conduct of process innovation. As process innovation at different life cycles may alter managerial incentive that leads to different firm performance, the managerial implication is that diversified firms should appropriately engage in process innovation to prevent unfavourable liability from the development of their businesses.     

高职科研管理工作创新的对策思考

教学是立校之本，科研是强校之基。重视高职院校的科研工作，加强科研管理创新至关重要。高职院校的科研工作从课题的选题、申报、立项、中期监督以及结题，直至最终的归档，每个环节都离不开科研管理工作。从高职科研管理工作中存在的主要问题出发，在实践探索的基础上，对高职科研管理工作创新提出了一些有价值的对策及建议。     

Understanding reflexive systems of innovation: An analysis of Swedish nanotechnology discourse and organization

We seek to understand how nanotechnology can contribute to the development of a more sustainable society in general, and to investigate Swedish nanotechnology in particular. On the one hand, the research interest is on how nanoscience can be turned into used products, that is, innovation. On the other hand, we acknowledge that innovation itself is the main producer of risk in modern societies. Inspired by sociology and economics of innovation, we try to capture this by introducing the term 'reflexive system of innovation' to denote a system made up of heterogenous elements, such as discursive components (expressions of knowledge and normative and regulative stands) and organizational components (actors and knowledge), evolving in a non-linear way through external influences as well as self re-enforcing and self-regulating processes. We present the evolution of a Swedish nanotechnology system from the 1980s to the present, as it moves through phases characterized by different kinds of discourse and organization. Evaluating the Swedish case against the concept of a reflexive system of innovation, we find advanced academic knowledge production but a lack of interconnectivity between actors, few actors outside the research community entering the system and a weak function of anticipation, guidance and risk handling. Broad national nanotechnology initiatives (NNIs) may be important for the crystallization of the desired processes, but because neither innovation nor risk can be fully contained, an NNI may only be part of the input to a fully fledged reflexive system of innovation in nanotechnology.     

Enhancing innovation through learning: the roles of market orientation and interorganisational knowledge stores

Drawing on the organisational learning theory, this study regards market orientation as a market-based learning and seeks to advance insight into how market orientation and interorganisational knowledge stores together affect different types of innovation. Our findings from a sample of 246 manufacturing firms provide supporting evidence for the positive effect of market orientation on both explorative and exploitative innovation. The effect of market orientation on innovation gets amplified when firms possess large amount of interorganisational knowledge, demonstrating the synergistic effect produced by different types of learning which is less known. This study, therefore, sheds light on the under-researched area of literature surrounding the interaction between different learning activities and the roles of knowledge from different sources on firm innovation.     

Generic innovation dynamics across the industrial technology life cycle: Platform equation modeling of invention and innovation activity

We describe here a generic approach to innovation dynamics based on an integrated framework for inventions and innovations applied via a platform equation and model across the industrial technology life cycle. We test the model for metals and other materials, and demonstrate that this model correctly describes the production activity for several materials and energy conversion technologies.Innovation activity patterns are shown for several oxides, metals, oil and wind energy and its derivatives. The metals Cu, Al, W, Mo and Pb are particularly studied for the amount produced over time. The total activity for the metals encompasses both the invention and innovation stage for a particular metal. Four major stages and two sub stages are identified for the discovery (invention) and subsequent growth regimes (i.e. the innovation stage). The pattern equation appears to clearly capture all these stages for the metals studied — work is ongoing for similar analyses of energy and other materials. Although the metals studied existed over differing periods (e.g. copper greater than 200 years whereas aluminum, just over 100 years), one single pattern equation appears to capture all the major trends. The use of the model is also shown for productivity analysis, especially for the condition of radical innovation (very rapid growth). For sustained radical innovation, namely, when the output of the produced material per unit time, keeps on increasing with time, there are various factors which may influence growth. For the conditions where thermal activation and plant size are the dominant variables, their impact on the growth may be examined in the context of the pattern equation. A preliminary analysis of oxide production activity also appears to follow this same innovation model.The results suggest a fertile field of future research extending the initial platform equation model to include R&D, Patents, and Performance, as well as Sales, as innovation activity. Further, the model shows promise in combination with the ARI methodology model for analysis and assessment of existing and future industrial technology life cycles involving material, process, product, software and service innovations.     

强度与指向：政府支持企业创新发展的注意力研究——基于中央科技政策文本的分析

政府支持企业创新发展的注意力变化及其分配对我国企业的创新发展具有重要的意义,而当前学界缺乏对此问题的深入探索。本文主要采用ROST CM 6.0软件对1983—2019年中央科技政策文本进行分析,总结提炼了此时期内中央政府支持企业创新发展的注意力强度与指向变化。结果表明：(1)中央政府支持企业创新发展的注意力强度经历了从“波动上升”到“相对稳定”的变化过程;(2)中央政府支持企业创新发展的施政重心经历了从“增强企业活力”到“创新驱动发展”的变化历程,不同时期中央政府对支持企业创新发展的认知以及需求存在差异,中央对支持企业创新发展的总体认知也在不断深化。(3)中央政府支持企业创新发展的注意力指向发生了明显转移,技术发展实现了从“重引进学习”到“创新驱动发展”的战略转型,制度建设则朝着从“重管理”到“重服务”的方向转变,体现了政府在“瘦身”的同时,为企业创新发展“放水养鱼”。     

Assessing the relationship between economic and ecological performance: Distinguishing system levels and the role of innovation

In this article we critically discuss the different perspectives that are currently in use for assessing the relationship between ecological and economic performance. Based on a review of the literature we propose that research up till now has made use of four distinct system boundaries: the firm, markets, production and consumption systems, and economic systems. Making these boundaries explicit is helpful in interpreting the mixed results that have been obtained. We describe the consequences of the choice for each of these system boundaries: and look at implications for innovation. We also argue that the production and consumption system boundary offers potential for further advances in the field and deserves more attention in future research.     

Evaluating innovation and labour market relationships: the case of Italy

In this paper the link between labour market flexibility andinnovation is analysed paying particular attention to the differenttechnological regimes of economic activities and the differentgeographical areas of the Italian economy. A dynamic panel dataspecification is used to assess the endogenous relationshipbetween patents, included as a proxy for innovation, and jobturnover and wages, which represent labour market indicators.Our results show that higher job turnover only has a significantand negative impact on patent activities in regional sectorsof Northern Italy, while blue and white collar wages have beengenerally found to have a positive and significant impact oninnovation.     

Evaluation of national science park systems: a theoretical framework and its application to the Italian and Spanish systems

Although many authors have analysed the role and the efficiency of science parks, only a few contributions have analysed national science park systems (SPSs) as a whole. Because of the lack of data, evidence regarding the performance of science parks in a nation is very limited and there is a lack of comparisons between different systems. This paper aims to introduce a simple framework to analyse SPSs and to show its use for comparing the state of development and the main differences of two or more SPSs. Its application to the Italian and Spanish systems shows that science parks play a more important role in Spain than in Italy. The main causes of these differences are argued to be (i) the presence of a set of coherent and particular policies which favour science parks in Spain and (ii) the internal factors of the Spanish science park system, including business models of the science parks and the role of the national association.     

Resolving the innovation puzzle of latecomers: the case of Taiwan

In the currently rapidly changing business world, innovation has not only become the key to survival and success, but also the defining challenge of organisations. For latecomer firms, however, because of their inherent resource constraints, innovation has become a far more complex undertaking, similar to a multidimensional puzzle. Although there have been an increasing number of practitioner-based surveys, a discrepancy still remains between academia and industry concerning the role and importance of R&D in innovation. Therefore, this study carried out an industry–university–institution survey of Taiwan, based on a multidimensional framework of the innovation puzzle: human, R&D, flow and connection. The results reveal several interesting clues and provide a better understanding of the innovation puzzle for latecomers, and more importantly, resolves the puzzle that could help latecomers identify where new opportunities lie and what weaknesses they must strengthen.     

Matthew effect,capabilities and innovation policy: the Argentinean case

The purpose of this paper is to test the presence of Matthew effects in different types of public funding for innovation – non-refundable grants, subsidized loans and tax credits. According to the literature, Matthew effect refers to the impact of past accessing to public funds on reputation, which increases the probability of accessing in the present. The dataset is made of 966 firms that accessed the Technological Argentinean Fund (FONTAR), main instrument to foster innovation in Argentina, during 2007–2013 – 3300 observations. Results confirm the existence of Matthew effects: past accessing to FONTAR increases the probability of accessing in the present, but only when different instruments are taken altogether. Then, Matthew effect is positively associated with the diversification of access to promotional instruments rather than the repeated access to one type of funding tool. Additionally, results show that firm’s innovation investments, R&D activities, and human resources, explain the increase in probability of accessing, which provides evidence regarding the presence of capability effects. All of this suggests that once the firm enters the system of public funding, it remains with an active innovative behaviour, not just because of reputation effects, but because it has accumulated capabilities in the pursuit of a technological advantage.     

The role of the financial sector in economic development: the Malaysian case

In this paper, we empirically examine the finance-economic development relations for the case of Malaysia. Using a battery of time series econometric techniques, we document robust evidence suggesting favorable output effects of financial market development. Likewise, there are consistent results showing the adverse real effects of financial volatility. The results of the development of financial intermediaries, however, are fragile. Moreover, the development of the financial markets hinges crucially on macro-economic performance and financial stability of the country. However, the process of financial market development is likely to be accompanied by financial volatility, leaving Malaysia with the trade-off between financial development and financial volatility. Lastly, we obtain limited evidence indicating the complementarity between financial market and banking sector developments.

Foucault,Weber and the history of the economic subject

Abstract

The present paper begins with a presentation of Foucault's lectures on economic issues. Departing from his previous views on government, Foucault offered a new approach to eighteenth-century liberalism and neo-liberalism, interpreting these political theories in terms of what he called biopolitics. Then the paper endeavours to demonstrate that the line of reasoning pursued by Foucault coincides with that found in Weber's sociology of religion. In as much as Weber studies the relation between the religious and the economic, the paper draws a parallel between the Weberian concept of ‘life conduct’ and the concept of ‘technique of the self’ advanced by Foucault in order to study the moral foundation of the economic agent.     

Homogeneity masquerading as variety: the case of horizontal innovation models

The literature on ‘horizontal innovation’ claimsto analyse cases where unbounded endogenous growth comes froman increasing variety of intermediate goods. The present papercontends that a good sample of representative models in thisliterature share two essential assumptions regarding productiontechnology, and that these assumptions together amount to assumingthe homogeneity of various intermediate goods. In these models,there is no variety of intermediate goods to increase owingto R&D activities; what increases is a mass of a singlehomogeneous intermediate good.