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危险废物因其成分复杂可能存在各种特殊风险,经过对相关案例进行事故分析,文章认为企业人员的认知能力可能是导致生产安全事故的一个关键因素。文章分析并简述了在安全管理中的认知方法。 相似文献
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质量管理为制药企业管理中的重点,借助信息化技术,对生产过程中的各类质量数据进行采集、贮存、整理、分析,沟通整合各板块,达到资源共享,简化管理流程,提高质量管理效率,最终达到全面管理,实现质量管理目标。 相似文献
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制药企业的科研机构管理特点与新思路 总被引:1,自引:0,他引:1
沈秉正 《中国医药技术经济与管理》2008,2(11):47-51
目的浅析制药企业科研机构的管理在整个研发工作中的重要性,并提出切实可行的改进办法。方法本文通过分析制药企业科研机构管理的功能及特点,从满足科研人员差异化需求的角度入手,并结合作者自身工作实践,提出制药企业科研机构管理的新思路。结果与结论制药企业科研机构的管理工作应同科研工作一样不断进步、不断创新。 相似文献
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Fundamental advances in the life sciences are exerting a profound influence on the structure of the pharmaceutical industry and the strategies of drug companies. The 'biological' revolution makes it possible to apply a scientific method to drug research. This paper argues that pharmaceutical companies can take advantage of the new method only if they encourage 'openness' of their research. We also offer a framework to explain why innovations in this industry increasingly result from networks of agents with complementary skills and resources. Greater use of scientific knowledge implies that important information for innovation can be expressed in relatively general and universal forms. This eases information exchange, and encourages specialisation and division of labour in drug R&D and marketing. Finally, the possibility of a division of labour in innovation opens new opportunities for medium-sized national pharmaceutical firms in Europe. Provided that they found their strategies on high-quality research in specialised niches, they can set up alliances with partners that possess complementary knowledge, and supply resources for clinical development and international marketing. 相似文献
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High-tech firms increasingly rely on inter-firm collaboration (IFC) in new product development (NPD). While there is a growing research interest in exploring the economic rationale of IFC through the transaction cost economics (TCE) and the resource synergy of IFC through the resource-based view of the firm (RBV), little attention has been given to the institution-based view (IBV) that also has important implications for firms’ choice of IFC. In particular, how national institutional environment affects IFC in the NPD process remains under-researched. This study aims to contribute to the literature by extending our understanding of the role of IFC in firms’ NPD process, taking into account transactional, resource, and institutional factors. Based on a case study of two firms: a state-owned and a private pharmaceutical firm in China, our research identifies three key forms of IFC, which are dynamic at different stages of NPD and contingent upon an array of institutional, resource, and transactional rationales underpinning firms’ choice of different forms of IFC. Our study is the first one that investigates the role of IFC in the NPD process bringing together the IBV, RBV, and TCE perspectives. 相似文献
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Knowledge and information flows in supply chains: A study on pharmaceutical companies 总被引:1,自引:1,他引:1
A great deal of attention in the supply chain management literature is devoted to study material and demand information flows and their coordination. But in many situations, supply chains may convey information from different nature, they may be an important channel companies have to deliver knowledge, or specifically, technical information to the market. This paper studies the technical flow and highlights its particular requirements. Drawing upon a qualitative field research, it studies pharmaceutical companies, since those companies face a very specific challenge: consumers do not have discretion over their choices, ethical drugs must be prescribed by physicians to be bought and used by final consumers. Technical information flow is rich, and must be redundant and early delivered at multiple points. Thus, apart from the regular material channel where products and order information flow, those companies build a specialized information channel, developed to communicate to those who need it to create demand. Conclusions can be extended to supply chains where products and services are complex and decision makers must be clearly informed about technology-related information. 相似文献
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Drug regulation and pricing have put strong pressure on the cost-benefit ratio of the innovative pharmaceutical industry. Therefore a study has been conducted in fourteen large and medium sized companies to determine some important organisational and managerial factors influencing success in pharmaceutical innovation. The study consists of structured interviews with Research Directors and questionnaires, submitted to the heads of the different research departments. The following conclusions are tentatively drawn. Firstly, the data suggest that a threshold investment of approximately $150–200 million is needed to maintain the innovative potential. Above approximately $750 million, 'economies of scale' seem to appear in pharmaceutical innovation. Secondly, an incremental strategy aimed at reducing the duration of the development process seems to be more successful than a radical strategy which lays more emphasis on discovery. Thirdly, pure play pharmaceuticals seem to be more successful than the pharmaceutical divisions of conglomerates. Management control, especially the way in which reorganisations are performed, is assessed more positively in pure play pharmaceuticals. Fourthly, the greater emphasis on human resources management in Anglo-American companies, in comparison to continental European companies, seems to be an important explanatory factor for their greater success on the pharmaceutical market. 相似文献
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2008年的金融危机席卷全球,关于在金融危机中中国制药企业怎样通过海外并购来进军海外做大做强,已经成为当下迫切需要研究的问题。本文对中国药企海外并购的必要性及可行性进行了深入分析,归纳了中国药企在金融危机下的海外兼并中的关键问题,在此基础上提出相应对策、 相似文献
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A survey of 45 leading pharmaceutical companies has been used to investigate aspects of their Research and Development (R&D) strategies, the allocation of resources including the financing and staffing of R&D functions, and the numbers of New Chemical Entities (NCEs) in the development process. The companies included the top ten by R&D expenditure in 1992 (top 10 companies). The study identified characteristics of leading companies and provided comparative data. The principal findings are that:
top ten companies had the highest R&D to sales ratios, progressed more NCEs after the drug candidate selection stage in 1992 and had achieved a greater geographical decentralization of staff than any other company.
Japanese companies differed in some respects from western companies, even those of a similar size. They operated with smaller clinical and regulatory affairs functions and made detailed plans for R&D expenditure further ahead than western companies, on average, more than 5 years compared with 3 years.
an increase in aggregated R&D staffing had occurred between 1990 and 1992 in 33 companies for which data for both years were available and staff numbers had decreased in only five of those companies.
top ten companies differed from others in their apparent productivity measured in terms of staff or R&D expenditure per NCE after the drug candidate selection stage, utilizing more staff and having greater R&D expenditure per NCE.
The results also appear to indicate early signs of a change in the structure of the industry according to R&D expenditure, which has since become more apparent. There was a distinct polarization by R&D budget size among the respondent companies: five companies were spending $900m or more on R&D in 1992 while the majority of the rest were spending less than a third of that amount. 相似文献
top ten companies had the highest R&D to sales ratios, progressed more NCEs after the drug candidate selection stage in 1992 and had achieved a greater geographical decentralization of staff than any other company.
Japanese companies differed in some respects from western companies, even those of a similar size. They operated with smaller clinical and regulatory affairs functions and made detailed plans for R&D expenditure further ahead than western companies, on average, more than 5 years compared with 3 years.
an increase in aggregated R&D staffing had occurred between 1990 and 1992 in 33 companies for which data for both years were available and staff numbers had decreased in only five of those companies.
top ten companies differed from others in their apparent productivity measured in terms of staff or R&D expenditure per NCE after the drug candidate selection stage, utilizing more staff and having greater R&D expenditure per NCE.
The results also appear to indicate early signs of a change in the structure of the industry according to R&D expenditure, which has since become more apparent. There was a distinct polarization by R&D budget size among the respondent companies: five companies were spending $900m or more on R&D in 1992 while the majority of the rest were spending less than a third of that amount. 相似文献
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Competition in the industries that develop complex products (such as aircraft engines and radar) depends on the integration of organizational systems as well as the pace of technological change.
Companies in these industries can be regarded as 'system companies'. A framework and taxonomy are developed to indicate the characteristics and types of companies and to understand how organizational learning and integration take place. This makes it easier for companies to anticipate strategic change and some implications of this kind are described. 相似文献
Companies in these industries can be regarded as 'system companies'. A framework and taxonomy are developed to indicate the characteristics and types of companies and to understand how organizational learning and integration take place. This makes it easier for companies to anticipate strategic change and some implications of this kind are described. 相似文献
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国际石油公司的全面风险管理 总被引:1,自引:0,他引:1
能源(石油)公司面临一个"风险金字塔".金字塔最顶端的市场宏观经济风险,很难被一个企业完全规避;中间层面的政策法规风险和行业竞争风险等,可以通过知法守法、制定和实施有效的公司战略来降低;金字塔最底层的公司日常业务运营中面临的各种风险,是公司进行全面风险管理的侧重点.风险管理是识别、测量、评估、呈报和控制所有可能导致公司蒙受损失的各种风险的过程.风险管理的基本目标,一是有效管理和提高公司承受风险的能力,二是将公司资源或资本按风险-回报率最大化原则分配使用.文章介绍了典型的国际能源(石油)公司的风险管理框架,以有效的公司治理和内部控制为基础的风险管理组织结构,风险管理的基础条件和流程,以及能源风险管理从控制职能发展成为战略管理工具的转变等. 相似文献
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文章阐述物业管理企业服务层次的概念,如何针对物业所有人与使用者的不同情况,准确地进行服务层次的定位,指出服务层次定位是否准确将是物业管理企业提高收益水平和最大限度地满足业主要求的关键所在。 相似文献