Managing liquidity in research‐intensive firms: signaling and cash flow effects of patents and alliance activities

The effective holding and management of liquid assets is critical to success in research‐intensive industries. The primary output of invention is new knowledge. However, because of its ‘sticky’ characteristics, knowledge may not easily diffuse to external shareholders, leading to knowledge asymmetries between managers/employees and external suppliers of capital. Many valuable R&D projects may thus fail to attract external financing, limiting a firm's ability to invest in R&D. In this study, we examine how the cash flow and signaling properties of a firm's patents and certain aspects of its alliance strategy can attenuate such problems. Specifically, we suggest that a firm's R&D investments positively predict the level of its liquid asset holdings. This is due to the fact that invention‐induced knowledge asymmetries increase the firm's cost of accessing external liquid capital. However, holding cash entails opportunity costs. In this regard, we also find that patent production and certain alliance activities provide important signaling mechanisms, which reduce knowledge asymmetries between the firm and capital markets, and consequently lower the firm's need to hold liquid assets. Empirical tests were conducted using a sample of 108 U.S‐based biotechnology firms. Copyright © 2009 John Wiley & Sons, Ltd.     

Comment on “fishing for sharks: Partner selection in biopharmaceutical R&D alliances” by diestre and rajagopalan

A recent study of R&D alliances between new biotechnology firms (NBFs) and pharmaceutical firms investigated how NBFs deal with the “swimming with sharks” dilemma involved in allying with firms capable of appropriating value. It concludes that NBFs are less likely to select alliance partners with related expertise because of greater appropriation risk. Based on our experience as NBF managers and a survey of NBF executives, we believe that such situations are uncommon, and that the study more likely shows pharmaceutical firms seeking diversification. Thousands of NBFs seek alliances with the top 100 pharmaceutical firms, and the larger company is much more likely to be the one to select among multiple potential partners. Copyright © 2013 John Wiley & Sons, Ltd.     

Response to mason and drakeman's commentary on “fishing for sharks: Partner selection in biopharmaceutical R&D alliances”

We respond to Mason and Drakeman's comment on our published paper titled “Are All ‘Sharks’ Dangerous? New Biotechnology Ventures and Partner Selection in R&D Alliances” (Diestre and Rajagopalan, 2012). We discuss both their survey analysis and alternative explanation and conclude that neither of them invalidates our theoretical premise and our empirical conclusions. Copyright © 2014 John Wiley & Sons, Ltd.     

Experience effects and collaborative returns in R&D alliances

Focusing on the link between prior alliance experience and firm benefits from R&D collaborations, this paper explores whether firms learn to manage their alliances. While prior experience should increase collaborative benefits from the current alliance, I expect these returns: (1) to be most beneficial when alliance activities are more uncertain; and (2) to diminish at high levels of experience. Results from a sample of 464 R&D alliances in the telecom equipment industry generally match these expectations. The positive benefits of prior experience in complex alliances suggest that a broader set of alliance management processes allows the firm to manage situations of ambiguity more readily. The lack of cumulative benefits from prior experience appears to be partly due to knowledge depreciating over time, since only recent experience has a positive impact on collaborative returns. Overall, these results provide empirical evidence of the effect of prior experience on collaborative benefits, both directly and conditionally on alliance characteristics, and have implications for learning to manage organizations more generally. Copyright © 2005 John Wiley & Sons, Ltd.     

国家产业技术政策、技术创新体系与产业技术创新战略联盟——兼论知识产权战略的作用机制

国家产业技术政策是国家为促进产业技术发展,建构产学研一体化的技术创新体系而实施的国家层面的指导性文件和纲领。国家产业技术政策与技术创新之间具有密切联系,建构产学研技术创新体系是实现国家产业技术政策的重要保障。其中产业技术创新战略联盟的建设则是实现产学研一体化技术创新体系和落实国家产业技术政策的重要战略性举措。     

HETEROGENEITY OF FIRM CAPABILITIES AND COOPERATIVE RESEARCH AND DEVELOPMENT: AN EMPIRICAL EXAMINATION OF MOTIVES

This article proposes capability heterogeneity of R&D consortia participants as a condition to distinguish two competing motives for cooperative R&D: cost-sharing vs. skill-sharing. An analysis of 398 questionnaire responses from participants in Japanese government-sponsored R&D consortia finds that the relative importance of the cost-sharing motive in R&D consortia increases when participants’ capabilities are homogeneous or projects are large, while the relative importance of the skill-sharing motive in R&D consortia increases with heterogeneous capabilities. The skill-sharing motive is likely to increase a firm’s R&D spending, implying an additional consideration for management’s evaluation of cooperative R&D participation, as well as adding a new public policy implication of cooperative R&D. © 1997 by John Wiley & Sons, Ltd.     

Electronic transportation marketplaces: a transaction cost perspective

Electronic transportation marketplaces (ETMs) are Internet-based mechanisms that match buyers and sellers of transportation services. With claims of reducing the administrative costs of transportation procurement to virtually nothing, the allure of ETMs is considerable. Shippers (transportation buyers) must therefore determine whether to pursue the new-founded opportunity and buy transportation services through an Internet-based intermediary or to buy services in a traditional manner. To date, there has been little structured thought on the topic to guide managers. Transaction cost economics (TCE) provides a robust framework toward this end. The TCE framework is adapted to present the procurement decision as one of “make” versus “buy.” The analysis is designed to help firms navigate their own determination to use an ETM and, when considered, the most appropriate form of ETM. The merits and caveats of ETM adoption are presented in the article.     

Are all ‘sharks’ dangerous? new biotechnology ventures and partner selection in R&D alliances

We examine how new biotechnology firms (NBFs) select pharmaceutical firms as R&D allies as a function of value creation and value appropriation considerations. We develop a theoretical framework to understand partnering decisions accounting for both, a potential partner's ability as well as incentives to appropriate and create value within an R&D alliance. Our empirical findings show that NBFs are more likely to ally with pharmaceutical firms with the ability to create value, as long as these firms have the incentives to use their skills to create rather than appropriate value. Our study highlights the double‐edged sword nature of value creation skills and provides a deeper understanding into the contextual factors that determine when potential R&D partners will perceive such skills as increasing appropriation risks. Copyright © 2012 John Wiley & Sons, Ltd.     

The role of strategic alliances in high-technology new product development

The authors examined 905 new product innovations introduced since September 1988 to determine the influences on product innovativeness, with a specific interest in strategic alliances, or cooperative strategies. Findings suggest that single firms, horizontal cooperative strategies, small and mixed'sized firms, biochemical industries, cross-industry product offerings, cross-industry cooperations, the progression of time, and European firms tend to indicate significantly more innovative products. Implications are proposed for business practitioners and researchers with specific application to the diffusion of innovation.     

Firm and environmental influences on the mode and sequence of foreign research and development activities

This paper develops an explanation for the mode and sequence of entry that firms select for their international research and development activities. The hypotheses are based on the internalization and evolutionary theory perspectives. I first hypothesize that there is a sequence to the mode of foreign research and development activities initiated. I then discuss two firm capabilities and alternatives which might cause firms to omit parts of the sequence. The context of the study is the foreign research and development activities of incumbents and recent entrants to the Japanese pharmaceutical industry. The results indicate intriguing differences between the motivations of established firms and new entrants in establishing foreign research and development activities. © 1998 John Wiley & Sons, Ltd.     

阀值效应:技术创新的低产业化分析--以中国医药技术产业化为例

技术创新遵循"阀值理论",即只有当研发资源集中到一定程度才能使研发成果成为稳定输出.我国企业规模小,销售收入少,销售收入中研发经费所占比重更低,少量的R&D经费被用在许多项目上,使得企业的新技术成果难以实现规模化的市场开发,难以实现产业化.本文的实证分析表明,R&D的投入存在着一定的"阀值效应",只有当流量、压力、能量都能够达到一定的"临界值",才能获得预期的市场效果.研发资源的极端分散化是目前我国高技术产业化发展的最大障碍,这从医药产业可以清晰地表现出来.欲使技术研发投入达到产业化要求,必须充分实现技术资源的集约化使用.     

基于交易成本分析的建设交易制度创新研究

借鉴已有的经济学研究成果,主要以交易成本经济学理论为分析工具,从交易规则和交易方式两个角度对建设交易制度的交易成本构成和产生机制进行了分析,最终的目的是达到交易成本的节约。在此基础上,提出了建设交易制度的创新思路：即完善建设法规;促进工程保险和工程担保制度的发展;建立有效的建筑市场准入制度和质量体系认证制度;选择或设计科学、合理的交易方式;科学设计或安排交易合同等。     

Behavioral assumptions and theory development: the case of transaction cost economics

From a critical realist perspective, I discuss the role played by behavioral assumptions in organization theories, and use transaction cost economics as an illustrative example. Core behavioral assumptions often constitute the foundation of the mechanismic explanations of a theory, and thus should play a pivotal role in theory development. I distinguish between assumption‐based and assumption‐omitted theory testing, and show that empirical research in transaction cost economics has been dominated by assumption‐omitted testing. To establish a solid foundation for a new theory, management researchers should pay more attention to assumption‐based testing. Copyright © 2006 John Wiley & Sons, Ltd.     

New product introductions below aspirations,slack and R&D alliances: A behavioral perspective

We develop hypotheses based on behavioral theory that explain how high technology firms' new product introduction (NPI) performance below aspiration levels impact the number of R&D alliances, and how slack moderates this relationship. Using panel data of U.S. biopharmaceutical firms, we find that as firms' NPI performance below historical aspiration levels increases the number of R&D alliances they form increases and slack intensifies this relationship. We contribute to alliance research by providing theory and empirical evidence that increases in the distance of NPI below aspirations serve as a motivation for increases in R&D alliances, and empirically to behavioral theory by revealing that NPI goals act similarly to financial performance goals in their impact on firms' actions and slack intensifies this relationship. Copyright © 2015 John Wiley & Sons, Ltd.     

Network patterns and competitive advantage before the emergence of a dominant design

This study examines the performance implications of the alliance networks of 49 firms that competed for two technology standards in the U.S. local area network industry from 1989 to 1996. During the race to define a dominant design, individual firms attract the suppliers of complements by building alliance networks to favor the firms' preferred technology standard. Controlling for the number of suppliers in each technology standard community and the extent of technical progress achieved by individual firms, the panel data analysis shows that central firms with high ego network density, coupled with a strategic intent to acquire and share knowledge broadly within the technological community, achieve better innovation performance. The size of the technological community and some random events in the early formation of the industry do not provide a sufficient explanation of how these firms gain the diverse support of suppliers or enhance their competitive advantage. By demonstrating the independent and contingent effects of alliance network properties, this study explains how network patterns might enhance or limit the benefits of alliance networks when focal firms embrace different innovation strategies. Copyright © 2009 John Wiley & Sons, Ltd.     

Collaboration and technology linkages: a strategic supplier typology

This study uses frameworks from the strategic management and operations strategy literatures to explore the relationships among collaboration, technology, and innovation in small and medium‐sized manufacturers. Statistical analysis of the responses of 200 New Hampshire manufacturing companies in four SIC code industries (fabricated metals, industrial equipment, electrical and electronic equipment, and instruments) leads to the development of a strategic supplier typology which is useful in explaining the differences in the composition and performance of various types of suppliers. Copyright © 2000 John Wiley & Sons, Ltd.     

跨国公司在华R&D机构的问卷调研——动机、职能与技术外溢渠道

本研究针对47家跨国公司在华R&D机构实施调研,运用7点Likert量表问卷获取第一手数据,通过因子分析、信度分析、聚类分析和Scheffe多重比较分析等统计方法,部分证实了“跨国公司R&D机构职能定位因R&D投资动机不同而存在差异”、“跨国公司R&D技术外溢渠道因R&D机构职能定位不同而存在差异”等两项研究假设。揭示出“全球技术型”R&D机构倾向于与本土机构开展研发合作,“技术转移型”R&D机构开展技术交流的意愿较低,“市场导向型”R&D机构对研发成本不敏感等检验结论,并在实证研究的基础上提出了相应的政策建议。     

Relative absorptive capacity and interorganizational learning

Much of the prior research on interorganizational learning has focused on the role of absorptive capacity, a firm's ability to value, assimilate, and utilize new external knowledge. However, this definition of the construct suggests that a firm has an equal capacity to learn from all other organizations. We reconceptualize the firm-level construct absorptive capacity as a learning dyad-level construct, relative absorptive capacity. One firm's ability to learn from another firm is argued to depend on the similarity of both firms' (1) knowledge bases, (2) organizational structures and compensation policies, and (3) dominant logics. We then test the model using a sample of pharmaceutical–biotechnology R&D alliances. As predicted, the similarity of the partners' basic knowledge, lower management formalization, research centralization, compensation practices, and research communities were positively related to interorganizational learning. The relative absorptive capacity measures are also shown to have greater explanatory power than the established measure of absorptive capacity, R&D spending. © 1998 John Wiley & Sons, Ltd.     

Know-how and asset complementarity and dynamic capability accumulation: the case of r&d

Dynamic capabilities enable firms to create new products and processes and respond to changing market conditions. This empirical investigation of dynamic R&D capabilities deals with the role of complementary know-how and other assets in the context of changing conditions in the U.S. petroleum industry during the 1970s and early 1980s. The analysis suggests that, in response to rising oil prices, firms with larger amounts of complementary technological knowledge and physical assets also undertook larger amounts of R&D on coal conversion (a synthetic fuels process). © 1997 by John Wiley & Sons, Ltd.     

Formation of R&D consortia: industry and company effects

This study investigates economic and strategic inducements of R&D cooperation. We focus on industry and company factors that affect a firm's rate of participation in R&D consortia. These factors are analyzed in a dynamic context using a sample of 312 Japanese firms in 74 industries between 1969 and 1992. We find a firm in an industry with weak competition and appropriability conditions has a higher rate of consortia participation. A firm's R&D capabilities, network formation through past consortia, encounter with other firms in product markets, age, and past participation in large‐scale consortia also positively affect its tendency of consortia formation. Copyright © 2002 John Wiley & Sons, Ltd.