Barriers to scientific and technical knowledge acquisition in industrial R&D

An understanding of how companies acquire external knowledge is important for any organisation which participates in technology transfer partnerships. The process of external knowledge acquisition within the development function of the pharmaceutical industry is described. Six pharmaceutical companies participated in this study. Group depth interviews were conducted with scientists from a wide range of disciplines and at different levels of seniority within their companies. Senior managers and information officers were interviewed individually. The findings indicated that, although this industry is a leader in formalised information services and commercial database usage, even here significant barriers to the acquisition of scientific and technological knowledge exist. In several of the companies examined the process of information acquisition is not addressed strategically and implemented at laboratory level.     

How mutuality reinforces partnership development: Japanese and Korean marketing perspectives

Relationship building is about ‘mutuality’ and how an organizational cultural value system enhances the development of long-term relationships that influence the marketing strategy process. This paper explains how senior managers embrace the concept of mutuality in order to establish a partnership arrangement in the context of a vertical marketing system. From the literature, four propositions relating to customer service policy, the process of innovation, relationship marketing and comparative national culture were developed and placed in the context of a Japanese and a South Korean electronics company based in the UK. The propositions were validated using in-depth, personal interviews with a limited number of senior managers in the two global companies. Evidence suggests that managers in Japanese companies formulate industry and country specific customer service policies, dictate R&D programmes, and spend a long time getting to know an individual in a potential partner organization(s) before they engage in any form of business integration. Whereas managers in South Korean companies are keen to communicate extensively and seek to acquire additional skills and knowledge so that they can innovate and implement cost effective strategies.     

虚拟研究与开发组织的理论及其在医药行业的实践

目的 为有效利用、整合现有资源,提升制药企业新药研究与开发能力提供参考,方法探讨虚拟研究与开发组织的理论及特点,结合新药研究与开发的特点,对我国应用虚拟研究与开发组织模式提升新药研发效率相关问题进行分析论证结果及结论虚拟研究与开发组织是一种适合我国制药企业新药研究与开发工作的新思路,制药企业可以选择三种模式进行虚拟研究与开发的实践政府可以通过建立合作研究中心推动虚拟研究与开发工作．     

Marketing and Organisational Innovations in Entrepreneurial Innovation Processes and their Relation to Market Structure and Firm Characteristics

This paper analyses the influence of marketing and organisational changes on the innovation process. Using data from the German community innovation survey 2007, two topics are investigated: First, we analyse whether firm and market characteristics trigger certain innovation strategies. Second, this paper investigates whether marketing and organisational innovations (MO innovations) are complementary to product and process innovations (PP innovations) or whether they are substitutes. Our results suggest that firms choose broad innovation strategies, which combine MO and PP innovations, if they have large internal resources and intermediate market power. We also find that marketing innovations make product and process innovations more successful.     

When Should RD&E and Marketing Collaborate? The Moderating Role of Exploration–Exploitation and Environmental Uncertainty

Collaboration between research, development, and engineering (RD&E) and marketing has traditionally been regarded as beneficial for new product performance (NPP). However, some studies have pointed out the drawbacks of excessive collaboration. Because collaboration simultaneously presents costs and benefits that vary with conditions, a contingent view of managerial practices suggests that the optimal level of integration should vary according to some factors that indicate when high levels of collaboration are preferable to lower levels. Although the literature on the many different factors that may impact the desirable level of collaboration is abundant, only a few studies have investigated the role of the peculiar characteristics of the new products being developed. This is at odds with several calls for future research on the role of the characteristics of the new product. This paper investigates the moderating role of an explorative versus an exploitive innovation program. It also controls for the moderating role of environmental uncertainty, which has been traditionally considered a moderator of the relationship between RD&E–marketing collaboration and new product program performance. The paper also investigates how a firm's innovation posture—a cultural trait—influences both directly and indirectly, via marketing's technical knowledge, RD&E–marketing collaboration. Indeed, several scholars have recognized that cultural differences create the main barrier between RD&E and marketing. Hence, a firm's culture should have an impact on the cultural barriers between the two departments. Further, the firm's innovation posture affects the extent to which the departments have to share resources and exchange information. In their seminal work, Gupta, Raj, and Wilemon argue that resource dependency is the main factor affecting the integration achieved between RD&E and marketing. Hence, an analysis of a firm's innovation posture is required to gain a deeper understanding of the antecedents of the collaboration between the two departments. The antecedents and effects of RD&E–marketing collaboration are tested in a sample of 80 companies operating in the U.S. auto industry through partial least squares. The paper shows that the extent to which a company develops explorative rather than exploitative innovations is a better moderator than environmental uncertainty in the relationship between RD&E–marketing collaboration and new product program performance. This contradicts much previous literature and sheds light on a partially neglected construct in the new product development literature. Second, the paper demonstrates that firms with a more aggressive innovation posture tend to develop greater collaboration between RD&E and marketing. Also, the marketing department tends to have a better understanding of the RD&E processes and capabilities in companies with an aggressive innovation posture than in companies with a defensive one.     

纺织服装企业营销系统组织创新研究——以陕北地区毛纺织服装企业为例

国内纺织服装企业适应市场能力普遍较弱,市场淘汰率较高,大多数还处于职能式进行单一的产品生产,市场反应能力较差。纺织服装企业要提高市场竞争力,就必须建立起科学、合理的营销组织机构,通过组织创新,合理地配置资源,提高企业的营销能力,从而提升企业的市场竞争力。本文在对陕北毛纺织服装产业进行深入调研的基础上,结合理论分析与实证研究,通过结构方程模型(SEM),分析了毛纺织服装企业在营销组织创新时存在的问题以及营销组织创新与营销能力和绩效间的关系,为陕西省服装企业提升市场竞争力提供具有针对性的对策建议。     

The globalization strategies of business-to-business born global firms in the wireless technology industry

This paper discusses the globalization process of business-to-business born globals in a rapidly growing industry, the wireless technology industry. Deviations in these patterns in regards to the mainstream pattern of internationalization and earlier born global literature are discussed. Furthermore, the roles of the founders and managers, the networks, the financial resources of the companies, and the innovations behind the companies under consideration are analyzed. A conceptual framework and propositions explaining the product, operation and market strategies of born globals are developed. The results suggest that born globals in the wireless sector do in fact deviate from the traditional internationalization process in many areas. Their expansion even to distant markets is rapid and they apply advanced product strategies at an early stage. However, their business operations are found to proceed at a more conventional pace and the notable difference from traditional firms is the rapid establishment of sales and marketing subsidiaries. Results emphasize the key role of the resources and capabilities of born globals in influencing the advancement of product categories, operation strategies, and global market presence. Born global firms were found to lack the resources and capabilities accumulated by traditionally internationalizing firms, and they therefore need to acquire them either through the earlier experience of the founding team, which should be complementary in nature, or from external domestic and international network actors.     

提高中国医药科技国际竞争力途径——中国医药行业研发联盟现状研究

近几年对中国医药行业研发（R＆D）联盟的研究集中于理论模型和策略,对其实践状况的系统研究还很缺乏。本文通过对中国医药行业R＆D联盟的回顾性文献综述和相关信息的整理分析,总结医药R＆D研发联盟近十年在中国的现状,并提出相关建议：“产、学、研”三结合研发新药;政府与商会进行协调;促进科技成果向现实生产力转化;促进R＆D联盟市场化。     

A shift to external alliances for product development in the pharmaceutical industry

For a number of years, pharmaceutical companies have been departing from a tradition of strict vertical integration, looking to external sources for at least some of their novel technology and products. The aim of this study was to determine whether (1) this is a long term, industry-wide trend, or (2) merely a temporary or local response to acquire the technical capabilities of the biotechnology revolution of the 1970's, after which, with the new generation of technology in-house, they will revert to primarily in-house innovation. Analysis of secondary data on a representative sample of the fifteen largest drug companies in the United States, the United Kingdom, Germany and Switzerland indicated that between 1977 and 1987, these pharmaceutical companies increased their external R&D alliances nearly six-fold on average. A large and growing proportion of pharmaceutical companies' R&D alliances are formed with biotechnology firms which have proprietary technology, due to financial and innovative pressures. Far from being temporary, this resort to external sources of technology in the pharmaceutical industry follows the trends of the wider industrial world towards functional specialization. Thus, biotechnology companies are increasingly taking on the role of suppliers of innovation.     

Structural social capital evolution and knowledge transfer: Evidence from an Irish pharmaceutical network

Businesses are becoming increasingly involved in collaboration networks to access external knowledge and sustain innovation. In this context, knowledge and knowledge transfer are considered an important source of innovation and competitive advantage. Social capital theory offers a theoretical approach to explain how individuals, groups, and organizations manage relationships and access knowledge resources. The structural dimension of social capital has stimulated debate regarding optimal network configuration to achieve innovation. The extant literature suggests network structures evolve from a bridging configuration to a bonding configuration without examining the details of how the evolution occurs within the network and its stage-by-stage impact on knowledge transfer. This study explores this relationship by analyzing the evolution of a successful Irish pharmaceutical network involving organizations from industry and academia. This research setting encompasses a rare network configuration in an industry known for its lack of collaboration among competing firms. Findings show that structural holes provide access to a set of complementary and heterogeneous knowledge. However, for such knowledge to be exploited, the network configuration has to evolve from a sparse network (small in size and characterized by weak ties across multiple organizational networks), to a large and cohesive network configuration characterized by high levels of commitment, trust, fine-grained information exchange, and joint problem solving. Mechanisms crucial to this evolution include consistently-scheduled meetings, training to communicate tacit knowledge, wide diffusion of knowledge through an on online portal, and relationship specific investments designed to safeguard intellectual property. Surprisingly, industry members appear to transition to a cohesive network faster than do academic members.     

Creating shareholder value via collaborative innovation: the role of industry and resource alignment in knowledge exploration

Collaborative innovation provides firms with a privileged opportunity to perform exploration in an externally oriented mode. The central challenges in exploration via collaborative innovation lie in the selection of relevant partners and in gaining access to potentially valuable external knowledge that the focal firm lacks. This article focuses on two aspects of inter-organizational alignment that affect knowledge differences and may thus help explaining the shareholder value implications arising from collaborative innovation: industry and resource alignment. Relying on data covering 97 bilateral collaborative innovations (194 innovation partners) in R&D intensive high-technology industries, we used event study methodology and follow-up hierarchical regression analyses to test our conceptual framework. With regard to industry alignment, results suggest that investors value greater industry distance between collaborating partners, especially when the partner firm provides high-level R&D resources. Furthermore, the results show a positive effect of supplementary resource alignment (i.e., a focal firm's R&D resources are supplemented by a partner firm's R&D resources) and, notably, a negative effect of complementary resource alignment (i.e., a focal firm's R&D resources are complemented by a partner firm's marketing resources) on investors' valuation of the collaboration's expected future performance. They, thus, contribute to research on shareholder value implications of collaborative innovation. From a managerial perspective, the study provides a better understanding of partner selection and shows how managers should position a collaboration to signal the shareholder value-creating potential to investors.     

创业板上市公司基于新指标视角的发展能力评价模型及应用研究

本文以创业板355家上市公司为研究样本,结合创业板公司自身特点,从基本指标和发展指标视角设计创业板公司发展能力评价模型,基本指标包括营运能力指标、盈利能力及偿债能力指标,发展指标包括创新研发能力、企业管理技术阶层和全体职工基本素质水平,企业发展前景和企业创利能力等。依据所建模型采用因子分析法对创业板公司的发展能力进行综合评价,并根据因子分析结果将样本公司分为发展能力高低两组,分别从所属行业、资本结构、公司业绩因素、公司创新能力影响因素方面对两组样本公司进行对比分析。研究的主要结论：（１）创业板的355家样本公司总体发展能力较弱,主要原因是我国创业板上市公司两级分化现象较为严重,其中创新能力、营运能力和行业发展能力相对较差。（２）我国创业板上市公司中第一大行业信息技术行业集中度较高并且成长持续性效果较好,而第二大行业新材料与新能源行业成长持续性较差,究其原因是我国新材料与新能源是新兴起行业,行业总体水平较差,需要加强研发。     

A research and development decision model for pharmaceutical industry: case of China

This paper evaluates prospective technology areas, development strategies, and various innovation resources in China's pharmaceutical sector through the use of a hierarchical decision model. The results indicate that although domestic SMEs are the major preferred innovation alternative, it is followed closely by foreign MNCs. The sensitivity analysis indicates that the effectiveness of policy decisions are influenced by certain high technology areas. Recombinant therapeutic proteins, recombinant vaccines, and monoclonal antibody technologies are identified as the major areas that will influence the priority of innovation resources. The research crafts a research framework to formulate innovation strategies in dealing with the uncertainties of technology development and policy decisions in the biopharmaceutical industry.     

Beating the odds in the innovation arena: The role of market and technology signals classification and noise

Innovation is a risky business. Notwithstanding the attention in research on the determinants of innovation success, the estimates of the extremely high failure rates (ranging from 40% to 90%) have not come down. As a result, new approaches have to be found to address the issues that prevent organizations from reaching innovation success over a longer period of time. In this study, Signal Detection Theory (SDT) is introduced to show that it may be less important to improve innovation practices in companies, than it is to change the nature of the projects that enter the corporate innovation funnel. In our empirical study of 44 innovation projects in the pharmaceutical and electronics industry, we show that pursuing more noisy signals (uncertain technological and market opportunities) is currently beneficial for innovation success. In general, companies allocate too few resources to noisy innovation opportunities. Interestingly, we find a positive, and not an inverted U-shaped, relationship between noise/signal ratios and innovation success. This indicates that there are almost no companies that take too much risk in the current competitive environment and that many can gain from increasing their noise tolerance. The implications from this study are quite counter-intuitive in a sense that ‘risk’ is not the cause of the innovation problems, but may be a solution.     

The Role of Marketing Resources in Radical Innovation Activity: Antecedents and Payoffs

While radical product innovations represent significant engines of firm growth, questions remain over whether marketing helps or hurts (1) a firm's radical product innovation activity and (2) its rewards from radical product innovation activity. By attaching an attention‐based view of the firm to a market‐based assets view of marketing, this paper examines the role of three marketing resources—market knowledge, reputation, and relational resources—on radical innovation activity. Our conceptual framework posits differentiated effects among marketing resources as antecedents of radical innovation activity and as moderators of its impact on firms' financial performance. Using a survey of a broad set of high‐tech business‐to‐business (B2B) firms to test hypotheses, it is found that firms with strong relational resources enjoy a higher propensity for, and stronger financial rewards from, radical innovation activity. Reputational resources come with a trade‐off as they hurt the incidence of radical innovation but enhance its financial rewards. However, market knowledge resources appear to hurt both radical innovation activity and its financial rewards. Our results point to the multifaceted role of marketing in radical innovation activity, which is unlikely to come with a single benefit or liability as prior work often posits. Rather, our research heightens the alertness of managers to assess their firms' marketing strength as a bundle of stocks of several marketing resources. Managers must understand the distinct benefits and drawbacks of each resource in developing and launching radical innovations. Our research underscores the differentiated value of marketing in radical innovation activity in B2B high‐tech contrary to the entrenched idea of a limited or even stifling role of marketing in this context.     

New Product Development in the Pharmaceutical Industry: Pooling Network Resources

Pharmaceutical innovation increasingly involves some pooling of resources of finance, equity, technology, information, and intellectual property between pharmaceutical companies and other organizations. The organizations and their exchanges constitute a network which can be regarded as a growing store of these varied resources preferentially accessible to network members. D. Jane Bower examines some network effects in management decision making in Ciba-Geigy (Switzerland) and Elan Corporation (Ireland). She concludes that participation in a common network has enabled these firms to access a pool of resources of knowledge, experience, and finance. This pool has been generated by past exchanges among network members, including providers of finance, and has increased the network's collective reservoir of knowledge.     

Exploring Correlates of Product Launch in Collaborative Ventures: An Empirical Investigation of Pharmaceutical Alliances

This paper examines collaborative ventures leading toward the launch of new products in the pharmaceutical industry. These collaborative ventures are one of the most underresearched areas in the new product literature, yet the preponderance of these collaborative ventures makes it an area of great importance for scholars and practitioners alike. As such, the purpose of the study is to examine why some collaborative projects produce a favorable outcome (the launch of a product) whereas others do not. That is, what characteristics of partner firms in the collaborative ventures and what characteristics of the partnership lead to a successful launch of a new product in the pharmaceutical industry? Secondary data from the pharmaceutical industry are employed in a multinomial logit model. Data from 128 collaborative ventures from 1980 to 2004 are used in the analysis. The partner firms in the collaborative ventures are from various industries ranging from malt beverages to pharmaceutical preparations to electronic and other equipment among others. Of the 128 collaborative ventures, 66 were successful in leading to a new product launch, whereas 62 did not result in the launch of a new product. The results from the multinomial logit analysis suggest that combined marketing resources of parent companies, combined technological intensity of parent companies, and combined asset bases of parent companies contribute to the likelihood of an eventual product launch in a collaborative venture. However, the results of the analysis show that contrary to expectations, technological complementarity of partners in the collaborative venture is not a significant predictor of successful new product launch. The results of the study suggest certain aspects for managers to consider when establishing collaborative ventures. To maximize the possibilities of the collaborative venture leading to the successful launching of a new product, managers should be concerned with the resources potentially available to partners in the collaborative venture from parent firms. These resources are not only of financial nature but also of technological nature. The existence of these resources does not ensure provision of resources to the collaborative venture; however, without the possibility of these resources it appears that successful launch of a product is less likely.     

Learning Capability,Technological Parity,and Innovation Mode Use*

The purpose of this research was to examine whether a firm's learning capability interacts with industry technological parity to predict innovation mode use. Learning capability is conceptualized in the current research as a firm's ability to develop or acquire the new knowledge‐based resources and skills needed to offer new products. Industry technological parity is conceptualized as the extent to which similarity and equality exist among the technological competencies of the firms in an industry. Three generic modes of innovation are considered: internal, cooperative, and external innovation. These modes reflect the development of new products based solely on internal resources, the collaborative development of new products (i.e., with one or more development partners), and the acquisition of fully developed products from external sources, respectively. The premises of this research are that (1) technological parity can create incentives or disincentives for innovating in a particular mode, depending upon the value of external innovative resources relative to the value of internal innovative resources and (2) firms will choose innovation modes that reflect a combination of their abilities and incentives to innovate alone, with others, or through others. Survey research and secondary sources were used to collect data from 119 high‐technology firms. Results indicate that firms exhibit greater use of internal and external innovation when high levels of industry technological parity are matched by high levels of firm learning capability. By contrast, a negative relationship between learning capability and industry technological parity is associated with greater use of the cooperative mode of innovation. Thus, a single, common internal capability—learning capability—interacts with the level of technological parity in the environment to significantly predict three distinct innovation modes—modes that are not inherently dependent upon one another. As such, a firm's internal ability to innovate, as reflected in learning capability, has relevance well beyond that firm's likely internal innovation output. It also predicts the firm's likely use of cooperative and external innovation when considered in light of the level of industry technological parity. A practical implication of these findings is that companies with modest learning capabilities are not inherently precluded from innovating. Rather, they can innovate through modes for which conditions in their current environments do not constitute significant obstacles to innovation output. In particular, modest learning capabilities are associated with higher innovative output in the internal, cooperative, and external modes when industry technological parity levels are low, high, and low, respectively. Conversely, strong learning capabilities tend to be associated with higher innovative output in the internal, cooperative, and external modes when industry technological parity levels are high, low, and high, respectively.     

Innovations—Doomed to Fail? Investigating Strategies to Overcome Passive Innovation Resistance

The constant and successful market introduction of new products is of major concern to companies throughout all industries. However, empirical research points to high failure rates of innovations, indicating that most new products fail as they are rejected by consumers due to their resistance to innovation. Several studies have confirmed the importance of passive innovation resistance as a dominant barrier, which has to be overcome before new product adoption can start. However, empirical evidence on how to overcome passive innovation resistance is still lacking. This study intends to address this gap by evaluating the effectiveness of marketing instruments (i.e., mental simulation and benefit comparison) to reduce negative effects of passive innovation resistance on new product adoption. The results of a scenario‐based experiment (n = 679) confirm high effectiveness for both instruments. However, the effectiveness varied with the type of passive innovation resistance present. More specifically, mental simulation was found to be the most effective instrument in the case of cognitive passive resistance, whereas benefit comparison was found to be most effective in the case of situational passive resistance. Thereby, the effect of both marketing instruments was stronger the more radical the new product was perceived. Hence, companies should assess the type of passive innovation resistance that is predominant in their target market, and align their choice of marketing instruments that accompany a new product launch to most effectively overcome passive innovation resistance. Employing such new product launch tactics should decrease initial market resistance and thus help companies in reducing innovation failure rates.     

In Search of Innovation and Customer‐related Performance Superiority: The Role of Market Orientation,Marketing Capability,and Innovation Capability Interactions

Understanding the mechanisms through which firms realize the value of their market‐based knowledge resources such as market orientation is a central interest of innovation scholars and practitioners. The current study contends that realizing the performance impact of market orientation depends on know‐how deployment processes and their complementarities in functional areas such as marketing and innovation that co‐align with market orientation. More specifically, this study addresses two research questions: (1) to what extent can market orientation be transformed into customer‐ and innovation‐related performance outcomes via marketing and innovation capabilities; and (2) does the complementarity between marketing capability and innovation capability enhance customer‐ and innovation‐related performance outcomes? Drawing upon the resource‐based view and capability theory of the firm, a model is developed that integrates market orientation, marketing capability, innovation capability, and customer‐ and innovation‐related performance. The validity of the model is tested based on a sample of 163 manufacturing and services firms. In answer to the first research question, the findings show that market orientation significantly contributes to customer‐ and innovation‐related performance outcomes via marketing and innovation capabilities. This finding is important in that market‐based knowledge resources should be configured with the deployment of marketing and innovation capabilities to ensure better performance. In answer to the second research question, the findings indicate that market orientation works through the complementarity between marketing and innovation capabilities to influence customer‐related performance but not innovation‐related performance. Managers are advised to have a balanced approach to managing the deployment of capabilities. If they seek to achieve superiority in customer‐related performance, marketing capability, innovation capability, and their complementarity are essential for attracting, satisfying, building relationships with, and retaining customers. On the other hand, this complementarity would be considerably less important if firms placed greater emphasis on achieving superiority in innovation‐related performance. In contrast to many existing studies, this study is the first to model the roles of both innovation capability and marketing capability in mediating the relationship between market orientation and specific performance outcomes (i.e., innovation‐ and customer‐related outcomes).