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91.
Barriers to innovation are heterogeneous, of financial and non-financial nature. The importance of barriers to innovation and their actual influence on innovation depend on firms’ characteristics such as sectoral affiliation, technological behavior and their response to perceived obstacles to innovation. Firms either continue to engage in innovation, or they avoid the activity altogether. This paper explored the nature and perceived importance of the obstacles to innovation that firms confront, in a developing-country context; we build on survey data about firms in Mexico. Our findings suggest that two kinds of policy interventions should help offset a firm’s perception of barriers to innovation. On the one hand, policies should enhance the innovation capacity of firms interested in innovation; on the other hand, policies need to tackle factors that reduce the interest of firms in innovation. Policies that boost demand for locally generated innovations would assist in achieving both these goals.  相似文献   
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Aims: Although several therapeutic options are available for chronic immune thrombocytopenic purpura (cITP), little is known about the treatment of cITP in Brazil.

Materials and methods: A multi-center, retrospective chart review, observational study was designed to describe the treatment patterns, clinical burden, resources use, and associated costs for adult patients diagnosed with cITP and treated in public and private institutions in Brazil. Patient charts were screened in reverse chronological order based on their last visit post January 1, 2012. (All costs were calculated using 1.00 USD?=?3.9571 BRL, from February 2016.)

Results: Of 340 patient charts screened, 50 patients were eligible for inclusion in the study. Single-drug therapy (prednisone, dexamethasone, or dapsone) was the most commonly used treatment, followed by combination therapies (azathioprine?+?prednisone, azathioprine?+?prednisone?+?danazol, and prednisone?+?dapsone). Splenectomy was performed in 22% of patients after at least first-line treatment. Platelet count and number of bleeding episodes at diagnosis were 31,561.1/mm3 (SD?=?±26,396.1) and 40 episodes, respectively; in first-line, 92,631.1/mm3 (SD?=?±79,955.3) and 19 episodes, respectively; in second-line, 96,950.0/mm3 (SD?=?±76,476.4) and 17 episodes, respectively. Private system patients had a higher median cost compared to public system patients (USD 17.49/month, range?=?0–2,020.77 vs USD 9.51/month, range?=?0–192.64, respectively).

Limitations: This study does not allow conclusions for causal explanations due to the cohort study design, and treatment patterns represent only the practices of physicians who have agreed to participate in the study.

Conclusions: The data indicate that available therapeutic strategies for second- and third-line therapies appear to be limited.  相似文献   
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We investigate the relationship between math attitude and students’ math scores using data obtained from PISA 2012 and a 2SLS model. Math attitude is approximated by an indicator that takes into account intangible (parental attitude, student instrumental motivation and student math anxiety) and tangible (parental help in math homework) factors. The presence of one family member in a math-related career is our instrumental variable. We find that an increase of one standard deviation in math attitude increases the student score by approximately 30 points, a relevant effect since 40 points is the equivalent of one year of schooling.  相似文献   
96.
This paper provides original evidence on the impact of import penetration on wages of individuals performing manual/cognitive task-intensive jobs in the Pe  相似文献   
97.
We revisit the highly debated aid‐policy‐growth association. Our results overturn Burnside and Dollar's original findings by simply using new data over the same countries and years. Marginal effects from the extended sample (1962–2013) provide weak evidence that aid can promote growth in the presence of good policies. Post‐Cold War (1990–2013) analysis, however, reveals that aid can decrease growth at any level of policy. The overwhelming majority of the results suggest aid conditional on policy is ineffective. This debate continues because the results are highly sensitive to country‐year selection, choice of methodology, measurement of institutional quality, and growth rate measurement. (JEL F35, O23, O40)  相似文献   
98.
Since PHILLIPS (1958) wrote his landmark article on the relationship between money wage rates and unemployment, much work has been conducted concerning ‘Phillips’ curves'. While some writers, such as LIPSEY (1960), SAMUELSON and SOLOW (1960) and HANSEN (1970), remained relatively close to Phillips' original model, other strayed from it. BRECHLING (1968), DICKS-MIREAUX and DOW (1959), ECKSTEIN (1968), ECKSTEIN and WILSON (1962), HAMERMESH (1970), KUH (1967), PERRY (1966), PHELPS (1968), and TAYLOR (1970) are a few researchers who felt Phillips' formulation did not adequately explain changes in money wage rates. Their approaches ranged from formulating entirely new models to merely adding other explanatory variables to Phillips' model.

The present study estimates a Phillips' curve for the United Kingdom within the framework of Phillips' basic hypothesis. He grouped all observations according to unemployment levels, averaged the wage changes for each group, and fitted a curve by trial and error to the compact body of data. The current approach fits a curve to all data points using a direct estimation procedure. Only two basic variables are used; money wage rates and unemployment.

REES and HAMILTON (1967) pointed out that the estimated relation between wage changes and unemployment is highly sensitive to the form of the variables and the regression employed. One can obtain widely scattered results by either changing the type of numerical analysis on existing data or by changing the defined variables. It would not be surprising if the results of the present analysis differ from previous works. Not only are some of the data sources different from those previously employed but the numerical analysis is entirely new to Phillips' curve theory. Spline theory is used to fit the Phillips' curve.  相似文献   
99.
We consider a set of asymmetrically informed agents, where the information of each trader is susceptible of being altered when she becomes a member of a coalition. For this, we consider a general rule that depending on the coalition, a signal (or an information partition) is assigned to each member of the coalition. We set examples showing that Grodal’s (Econometrica 40:581–583, 1972), Schmeidler’s (Econometrica 40:579–580, 1972) and Vind’s (Econometrica 40:585–586, 1972) core characterizations of a continuum economy may fail in this general informational setting. However, under mild assumptions on the rule, we extend Schmeidler’s and Vind’s results to economies that allocate information to agents in each coalition according to the rule. We then focus on information mechanisms based on the size of coalitions and provide a general characterization result for the corresponding cores. Moreover, we pay close attention to the rule that assigns the shared information to each member of specific coalitions. We prove that the resulting cores are exactly the same independently of whether arbitrarily small or large coalitions share information.  相似文献   
100.
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