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131.
Neeta Tandon Luis A. Balart François Laliberté Dominic Pilon Patrick Lefebvre Guillaume Germain 《Journal of medical economics》2014,17(12):862-871
Background:Chronic hepatitis C (CHC) is associated with significant economic burden. This study evaluated the healthcare cost alleviation associated with treatment of CHC.Methods:Health insurance claims from 60 self-insured US companies were analyzed (01/2001–03/2012). Adult patients with ≥1 CHC diagnosis (ICD-9-CM: 070.44, 070.54), initiating interferon, and with ≥2 dispensings and with ≥48 weeks of follow-up were selected. Patients diagnosed with HIV or who completed only 24 weeks of interferon therapy (a surrogate for CHC genotypes 2 and 3) were excluded from the study. Interferon users were categorized into complete and discontinued therapy cohorts. During the post–48-week treatment period, cohorts were compared for healthcare resource utilization using rate ratios (RRs), as well as healthcare costs using per-patient per-year (PPPY) cost differences.Results:A total of 1017 patients who completed and 953 patients who discontinued interferon therapy were identified. Relative to the discontinued therapy cohort, the completed therapy cohort had significantly fewer hospitalizations (RR [95% CI]?=?0.74 [0.68, 0.81], p?0.001), outpatient visits (RR [95% CI]?=?0.92 [0.91, 0.93], p?0.001), and ER visits (RR [95% CI]?=?0.93 [0.87, 1.00], p?=?0.039), which translated into significantly lower total healthcare costs PPPY (cost difference [95% CI]?=?$4540 [1570, 7680], p?=?0.004) and hospitalization costs (cost difference [95% CI]?=?$3039 [1140, 5248], p?=?0.002). Non–CHC-related costs accounted for 55% and CHC-related costs for 45% of the all-cause cost difference between cohorts.Limitations:Claims data may have contained inaccuracies, and genotypes of patients with CHC could not be confirmed. The study consisted of privately insured individuals and may not be generalizable to the entire CHC population.Conclusion:Compared to discontinued therapy patients, CHC patients who completed interferon therapy and presumably had a higher rate of achieving SVR were found to have lower levels of healthcare resource utilization and costs post-therapy. The reduction was primarily in costs associated with non–HCV-related comorbidities. 相似文献
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134.
Gilles?DufrénotEmail author Aurélia?Jambois Laurine?Jambois Guillaume?Khayat 《Open Economies Review》2016,27(5):923-944
This paper proposes a regime-dependent model to estimate fiscal multipliers in the US. Output, consumption and investment are assumed to respond to tax and spending changes in a nonlinear manner. Fiscal multipliers are time-varying because their size and sign depend upon the state of the economy (upturns and downturns). Keynesian effects appear essentially during downturns, while anti-Keynesian effects are observed during expansions. Transfer payments contributes to a higher private consumption when they are given to consumers in bad times. Reducing taxes boosts consumption in good times. Investment responds positively to lower taxes during downturns, but negatively in the upturn regime. Our results thus suggest that Keynesian effects have been associated to expansionary policies during recessions, while anti-Keynesian effects were observed during expansions illustrating situations of expansionary fiscal consolidation. The effectiveness of fiscal positive impulses increases in downturns relative to upturns. A corollary is therefore that austerity measures during recessions would have detrimental effects on the GDP and its components. 相似文献
135.
Summary. We consider the problem of efficient insurance contracts when the cost structure includes a fixed cost per claim. We prove
existence of efficient insurance contracts and that the indemnity function in such contracts is non-decreasing in the damage.
We further show that either there is no insurance, or the indemnity is positive for all losses, or efficient insurance contracts
have a unique jump. We study variants of the model and provide a generalization to the case of non expected utilities. Our
results are then applied to Townsend's model of deterministic auditing.
Received: November 8, 2000; revised version: March 12, 2002
RID="*"
ID="*" We are grateful to F. Salanié for pointing out an error in the previous version of the paper and for suggesting Proposition
6 to us.
Correspondence to: R.-A. Dana 相似文献
136.
Summary. In simple models of borrowing and lending with ex-post asymmetric information, Gale and Hellwig (1985) and Williamson (1986) have shown that optimal debt contracts are simple debt contracts where borrowers repay a fixed interest rate whenever possible and lenders seize all the profit when borrowers default. In this note, we depart from their works by assuming that borrowers and lenders have heterogeneous beliefs, and show that simple debt contracts do not necessarily survive as optimal contracts.JEL Classification Numbers:
G3, D8. 相似文献
137.
This research aimed to investigate the possible relationships between the concepts of consumer loyalty (attitudinal and behavioral), satisfaction, and team identification in the context of sport spectatorship. Specifically, several models were tested to investigate (1) the direct influence of team identification, consumer behavioral loyalty, and consumer satisfaction on consumer attitudinal loyalty, and (2) the mediating or moderating role of team identification in the relationship between consumer satisfaction, behavioral loyalty, and attitudinal loyalty. Results from a sample of 395 spectators of French ice hockey first division clubs revealed that consumer transaction–specific satisfaction was found to be the stronger predictor for consumer attitudinal loyalty alongside team identification and the average number of home games attended per year. A second indirect route is possible because team identification was also found to play a mediating role between consumer transaction–specific satisfaction, home and away games attended per year, and some dimensions of consumer attitudinal loyalty. Finally, team identification was also found to moderate the impact of consumer satisfaction and the number of away games attended on different facets of attitudinal loyalty. Marketing and theoretical implications are discussed. © 2011 Wiley Periodicals, Inc. 相似文献
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139.
Sanvi Avouyi‐Dovi Françoise Drumetz Jean‐Guillaume Sahuc 《Bulletin of economic research》2012,64(3):377-392
This paper sets out to re‐examine the money demand function for the euro area. Traditional specifications often yield unsatisfactory results: instability of short and long‐term coefficients; relatively large differences between estimated and actual value of variables; and significant changes in the number of long‐term relationships, etc. Using a standard Vector Error Correction Model, we find that the usual specification is indeed unstable. However, introducing a European equity price gives rise to a more stable system. Furthermore, recursive estimates confirm the relative stability of long‐term coefficients. Estimates of the real money gap, based on the money demand equation including equity prices, point to moderate, albeit persistent, excess liquidity in the euro area in recent years. The real money gap contains information about future inflation but this content may have diminished since 2001. 相似文献
140.
Guillaume?R.?Fréchette John?H.?KagelEmail author Massimo?Morelli 《Economic Theory》2012,49(3):779-800
We experimentally investigate a legislative bargaining model with both public and particularistic goods. Consistent with the
qualitative implications of the model: there is near exclusive public good provision in the pure public good region, in the
pure private good region minimum winning coalitions sharing private goods predominate, and in the “mixed” region proposers
generally take some particularistic goods for themselves, allocating the remainder to public goods. As in past experiments,
proposer power is not nearly as strong as predicted, resulting in public good provision decreasing in the mixed region as
its relative value increases, which is inconsistent with the theory. 相似文献