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161.
The advertising budget allocation decision has been recognized as a critical decision that should receive logical, scientific determination. However, actual decision-making practice indicates that marketers typically use qualitative, non-scientific methods when setting advertising budgets. This article discusses the reasons for this practice by focusing on the properties of qualitative models which make them attractive to practitioners and the properties of quantitative models which make them unattractive. To assist in this analysis, a taxonomy for the classification of various qualitative and quantitative budget models is constructed, the emphasis of which is on the perceived usefulness of a budget model to practitioners. 相似文献
162.
J. Maervoet N. Bossers R. P. Borge Jr S. Thompson Hilpert A. van Engen 《Journal of medical economics》2013,16(11):1221-1234
AbstractObjectives: Atrial fibrillation (AF) is the most common arrhythmia and a major marker of ischemic stroke risk. Early detection is crucial and, once diagnosed, anticoagulation therapy can be initiated to reduce stroke risk. The aim of this study was to assess the cost-effectiveness of employing an insertable cardiac monitor (ICM), BIOMONITOR, for the detection of AF compared to standard of care (SoC) ECG and Holter monitoring in patients with cryptogenic stroke, that is, stroke of unknown origin and where paroxysmal, silent AF is suspected.Materials and methods: A Markov model was developed which consisted of five main health states reflecting the potential lifetime evolution of the AF disease: post cryptogenic stroke (index event), subsequent mild, moderate and severe stroke, and death. Sub-states were included to track a patient’s AF diagnostic status and the use of antiplatelet or anticoagulant therapy. AF detection was assumed to result in a treatment switch from aspirin to anticoagulants, except among those with a history of major bleeding. Detection yield and accuracy, clinical actions and treatment effects were derived from the literature and validated by an expert clinician. All relevant costs from a US Medicare perspective were included.Results and conclusions: An ICM-based strategy was associated with a reduction of 37 secondary ischemic strokes per 1000 patients monitored compared with SoC. Total per-patient costs with an ICM were higher (US$90,052 vs. US$85,157) although stroke-related costs were reduced. The use of an ICM was associated with a base-case incremental cost-effectiveness ratio of US$18,487 per life year gained compared with SoC and US$25,098 per quality-adjusted life year gained, below established willingness-to-pay thresholds. The conclusions were found to be robust over a range of input values. From a US Medicare perspective the use of a BIOMONITOR ICM represents a cost-effective diagnostic strategy for patients with cryptogenic stroke and suspected AF. 相似文献
163.
This article argues that economics is currently undergoing a fundamental shift in its method, away from neoclassical economics and into something new. Although that something new has not been fully developed, it is beginning to take form and is centered on dynamics, recursive methods and complexity theory. The foundation of this change is coming from economists who are doing cutting edge work and influencing mainstream economics. These economists are defining and laying the theoretical groundwork for the fundamental shift that is occurring in the economics profession. 相似文献
164.
William Whipple Jr 《工程经济学家》2013,58(3):159-167
ABSTRACT There are many different notations used to describe industrial property mortality; some are mathematical formulas, while others use a graphical format. The Weibull distribution is a mathematical formulation and is commonly used in life testing and quality control. Because of the kinship of life testing and industrial property mortality, the Weibull distribution was selected as a possible distribution to describe mortality characteristics. Tests were performed to determine how well the distribution fulfilled this function. The results indicate that the Weibull distribution describes industrial property mortality patterns as well as the Iowa-type curves. On this basis, the distribution shows promise for use in life analysis. 相似文献
165.
166.
Vernon M. Briggs Jr. 《Journal of economic issues》2013,47(4):1301-1303
167.
Charles S. Jones Jr. M.D. 《North American actuarial journal : NAAJ》2013,17(1):56-63
Recent advances in genetic technology and progress in the multinational Human Genome Project are providing scientists with the ability to look into and manipulate the very makeup of life: the DNA molecule. We can already examine many dozens of plant and animal genes for disease producing abnormalities. In the near future, we will have the ability to alter specific genes in living tissue. This genetic technology holds great promise in our quest for preventing, diagnosing, treating, and predicting disease, not just in humans, but in all forms of life. But there are some problems. Philosophically many are not ready for the implications of this technology. There are social and ethical issues that have not been well addressed, and which have, in part, resulted in an unprecedented amount of legislative activity over the past four years aimed at restricting access to and use of genetic information. The ability of the U.S. insurance industry to risk-select may be severely hampered if these restrictions are widely applied. 相似文献
168.
Edsel L. Beja Jr. 《中国与世界经济(英文版)》2008,16(2):82-92
An examination of available data reveals large trade misinvoicing between China and its trade partners. The analysis finds a net trade misinvoicing of US$287.6bn between 2000 and 2005, while the full magnitude of unrecorded trade is estimated at US$1.4tn. China needs to establish more effective management of its international trade flows. At the same time, the international community needs to provide more effective governance mechanisms to address trade misinvoicing. 相似文献
169.
170.
William N. Pugh Sharon L. Oswald John S. Jahera Jr. 《Managerial and Decision Economics》2000,21(5):167-180
Employee Stock Ownership Programs (ESOPs) have long been promoted as a motivational tool: employees become profit‐minded owners. Latterly, however, more ESOPs are being used as part of a takeover defense: here the ESOPs main purpose is to put more company stock in friendly hands—the employees—who, like existing management, could suffer layoffs, etc. in a hostile takeover. We find that, as a group, only the takeover‐related ESOPs are associated with increased leverage (itself a takeover defense). Non‐target firms show no long‐term increase in debt‐to‐assets. We find little evidence to support the motivation hypothesis: while actual labor costs are lower for ESOP firms, after industry‐adjusting they tend to be unaffected or higher. We find that a few measures of firm financial performance [return‐on‐equity (ROE), return‐on‐assets (ROA), net profit margin (NPM)] do improve significantly, but this appears to be largely a short‐term effect. Industry‐adjusted holding period returns appear to be unaffected by the ESOP; however, ESOP firms that leverage show evidence of long‐term market underperformance. We conclude that ESOPs provide, at best, only a short‐term boost to corporate performance. Copyright © 2000 John Wiley & Sons, Ltd. 相似文献