Strategic alignment and organizational options in biotechnology firms

Biotechnology has created a number of oflfiortunities for new start-up firms. A feu of these fims have grown rapidly and have ambitious strategies. These strategies reflect the fim growing organizational competences i n the context of rapidly changing technological, competitive, Jinanczal and regulatory circumstances. The firms have pursued adaptive, learning-based strategies which give them advantages over large firms. Underpinning these strategies have been long-term efforts to establish a highly motivated and creative workforce. Using the examples fo the UK's two leading biotechnology firms, some of the features of these strategies are exumined. It is found that there are dgerences i n the organizational forms selected by the two fims. These reflect temporal factors, differing environmental conditioru, and elements of manugement choice. The difficulty oj strategic management in turbulent conditions 6s highlighted by considering some of the strengths and weaknesses of both options.     

External linkages and product innovation in small manufacturing firms

The requirement for small firms to collaborate, as a means to supplementing and complementing limited internal resources, has dominated much of the academic and policy debate on regional development and small firm innovation throughout the late 1980s and 1990s. However, relatively little empirical work has sought to look further than simple frequency enumeration - noting that the most innovative and better performing firms are generally more likely to have links with external organizations. Based upon a sample of 228 small West Midlands' manufacturers, this study considers the source, function, geography and strength of innovation-related co-operation. While the general findings point to innovators making greater use of external linkages, of certain types and in particular directions (notably the preponderance of vertical value chain linkages), the results are less emphatic than might have been anticipated. This leads to consideration of the factors contributing to and impeding joint innovation and the firms' perceptions of the impact of innovation. From this, it appears that much of the observed difference between innovators and non-innovators lies in less objective measures. The data suggest the importance of inter-personal dynamics, attitude and expectations in facilitating successful collaboration.     

Takeoffs

This paper identifies factors associated with takeoff—a sustained period of high growth following a period of stagnation. Countries that experience takeoffs average 2.3% annual growth following their stagnation episodes, while those that do not average 0%. Using probit, we find that de jure trade openness is positively and significantly associated with takeoffs. A one‐standard‐deviation increase in de jure trade openness is associated with a 55% increase in the probability of a takeoff in our default specification. Capital account openness encourages takeoff responses, but measures of de facto trade openness are found to be poor predictors of takeoffs. We also examine the determinants of nations achieving “sustained” takeoffs; i.e. those lasting eight years or longer. Takeoffs in countries with more commodity‐intensive output bundles are less likely to be sustained, suggesting that adverse terms‐of‐trade shocks may play a role in ending long‐term high growth episodes.     

Topical coverage in internal auditing: academic versus practitioner perceptions

This study reports the results of research that investigates whether a gap may exist between academic content and practitioner needs in the area of internal auditing within the USA. Questionnaires were sent to internal auditing faculty and practitioners to identify and quantify the perceived importance of 25 different internal auditing topics, as well as the use of case studies and practitioner classroom visits as pedagogical techniques. Groups were in substantial agreement on the relative importance of the topics. However, some specific topic differences were noted, with educators placing more importance on items including engagement planning, preliminary surveys, audit programmes, risk management and fraud. Practitioners placed more importance on the qualities desired in staff internal auditors, Certificate in International Auditing (CIA) examination preparation, and computer auditing. In addition, there was considerable agreement between the two groups on the use of case studies in the classroom, as well as classroom visits from practicing internal auditors.     

Socioeconomic variations in perceived barriers to recreation participation among would‐be participants

Abstract

The effects of fifteen barriers to participation were examined among people who expressed a desire for but were unable to participate in a new recreational activity. Work commitments, overcrowding of facilities, and lack of partners were the three main barriers. The effects of barriers were not perceived uniformly across the sample but varied between subgroups defined according to socioeconomic variables: the people most likely to be affected by barriers to participation included the poor, the elderly, and single parents. The extent to which recreation practitioners can and should respond to these kinds of research findings is discussed, and several ways in which the effects of barriers to participation might be modified or alleviated are evaluated.     

Comparing Costs and Risks of Retirement Plans for Sponsors

This stochastic simulation analysis compares funding costs and volatilities for private sponsors of traditional defined benefit (DB), pension equity (PE), cash balance (CB), and defined contribution (DC) retirement plans. Plan provisions of equivalent benefit generosity in the different plan types are determined. The modeling includes current funding requirements and practices as well as a comprehensive set of uncertainties in asset and labor markets. The results show that costs and risks for sponsors vary significantly with plan types, investment and funding strategies, and participant demographics. The hybrid PE and CB plans exhibit characteristics of cost efficiency, as in the DB plan, and risk reduction, as in the DC plan, for plan sponsors under conventional investment strategies. These features are more saliently observed in the CB plan, but it is also more difficult to implement effective asset–liability management strategies for it.     

The Policy Choices and Reaction Functions of Bank of England MPC Members

The results of an econometric exercise are presented, showing that Monetary Policy Committee (MPC) members appointed from outside the ranks of Bank of England staff (outsiders) react differently to forecasts of inflation and output than those appointed from within the Bank (insiders). All results are reinforced by the well‐established findings that, compared with outsiders, insiders choose higher interest rates, are more likely to vote as a bloc, and feature on the winning side of policy decisions more frequently. On the basis of these results, it is argued that the current MPC framework is biased toward the policy choices of insiders.     

General Price-level Adjustment: Some Properties of the Edwards and Bell Method

The method of general price level adjustment proposed by Edwards and Bell differs from the traditional CPP method, insofar as it enables historical cost profit to be reconciled with real accounting income (CPP profit) by two steps within a single simple statement. Edwards and Bell's contribution is clarified in this paper, by proving rigorously the two theorems which underlie their method of applying general price level adjustment to historical cost. A numerical example is used to illustrate pure historical cost, traditional CPP, Edwards and Bell general price level adjustment, and Ijiri's dual, which is found to contain similar information to the Edwards and Bell system. This is followed by a discussion of Edwards and Bell's preferred method of price level adjustment to a replacement cost base. This method of adjustment, applied to a current cost base, underlay FAS33 as modified by FAS82 in the USA. Finally, Edwards and Bell's historical cost base is compared with a recent British proposal for a one-line adjustment to capture the effects of inflation on historical cost profit. The simplicity of the latter proposal lies in the form rather than the substance of the information presented.     

ON THE ROBUSTNESS OF RANGE‐BASED VOLATILITY ESTIMATORS

We empirically examine Parkinson's range‐based volatility estimate in the federal funds market, which is unique because institutional regulations create a predictable pattern in interday volatility. We find that range‐based volatility estimates and standard deviations produce the expected volatility pattern. We also find that at trading pressure points where microstructure noise should be greatest, range‐based estimates are less than the standard deviations. Thus, we support the argument that range‐based volatility estimates remove the upward bias created by microstructure noise. We find that the Parkinson method is the most efficient range‐based volatility measure among a set of alternates in this market.