谈对会计利润与纳税所得差异的分析

企业会计制度是为了真实完整地反映企业的财务状况、经营业绩,以及财务状况变动的全貌,规范企业的会汁核算,保护投资者、他人及其他利益相天者的权益;而税法主要日的是取得国家的财政收入,对经济和社会发展进行调节,处理国家和纳税人之间的分配关系,确定企业应纳税所得额的.     

林业经济重点向林下经济转移的探究

根据林业经济发展现状和林下经济的发展趋势,大力发展林下经济,增加林业资源的产业附加值,改善整个林业经济发展运营.在探讨林下经济特点和国有林场发展林下经济优势的基础上,分析存在问题,探究林下经济的发展模式与发展对策.     

Valuing customers for social network services

In the current Internet environment, many online service companies based on community factors (networks) produce and sell new types of digital products. For example, SNS (social network service) companies now sell customers digital decorative products for the adornment of online avatars. Not only do individual customers consume these digital products, but they also exchange them as gifts in their local neighborhoods. While previous studies on customer valuation (e.g. CLTV, RFM, etc.) focus on some important issues for identifying valuable customers, the literature does not resolve issues related to the effects on customer value of products purchased as gifts for another person. This study attempts to verify empirically the effects of two representative social network properties (tie strength and the number of ties) on customer monetary value.This study selects 2615 customers from a South Korean SNS website who enrolled on the site on the same day. Data include diverse purchase-related information, social network properties in terms of gift-giving for six months, and demographic information. The primary results of this study are as follows. First, the proposed model, which includes social network properties, has a great deal more explanatory power than the baseline model — the RFM-based customer value model. Second, tie strength and the number of ties in a gift-giving network increase customer value. Third, tie strength has a more profound impact on customer value than does the number of ties. The results of this study theoretically expand the domain of customer valuation studies due to the inclusion of social network properties, and suggest important practical implications for some online SNS companies in their efforts to find valuable customers and improve customer value.     

新时期高职院校学生就业心理问题探讨

本文对高职院校学生在就业过程中常见的心理问题进行归类研究,在分析造成这些心理问题主客观原因的基础上,探讨如何从社会、学校和自身层面调适学生就业心理问题,帮助学生走出就业心理困惑,排除心理障碍,树立正确健康的人生观、价值观、职业观,从而实现顺利就业。     

基于新公共服务理论的广西邮政改革的对策研究

邮政业作为公共企业,是公共部门的重要组成部分,以新公共服务理论作为理论基础来研究广西邮政的改革问题具有深刻的内在必然性。本文对如何深化邮政政策进行较为全面的研究和探索。     

新自由主义思潮的全球化历程及其影响

新自由主义思潮在向全球扩张蔓延的过程中,对拉美、东欧和前苏联国家产生了巨大而深刻的影响。对新自由主义的危害,正处于改革发展关键阶段的中国应有清醒而足够的认识。     

Measuring living standards from the lowest: Height of the male Hangryu deceased in colonial Korea

The living standards in Korea during the colonial period (1910–1945) have been debated for a long time. We explored this problem using the height of the Hangryu deceased, a dead person who did not have any acquaintances to claim the body. We found that the height of male Hangryu deceased, ages 25 to 30, increased by 2.2 cm during the colonial period. This result is consistent with recent quantitative studies measuring income levels or demographic information. However, questions such as when this growth in height started and what initiated this pattern need further investigation.     

对农业适度规模经营实现形式和农业劳动力市场培育的探讨

中国要实现从传统农业向现代农业的转型,要走农业规模化、商品化和国际化的道路。本文基于我国农业坚持土地由国家和集体所有的制度安排,对推进适度规模经营的组织形式构建和培育农业劳动力市场等进行探讨。     

Economic modeling for the US of the cost-efficiency and associated expanded treatment access of conversion to biosimilar pegfilgrastim-bmez from reference pegfilgrastim

Abstract

Aims: For this economic analysis, we aimed to model: (1) the cost-efficiency of prophylaxis with biosimilar pegfilgrastim-bmez for chemotherapy-induced (febrile) neutropenia (CIN/FN) compared to reference pegfilgrastim, and (2) the expanded access to CIN/FN prophylaxis and anti-neoplastic treatment that could be achieved with biosimilar cost-savings on a budget-neutral basis.

Methods: In a hypothetical panel of 20,000 cancer patients receiving CIN/FN prophylaxis and using the average sales price (ASP) for the second quarter of 2019 for reference pegfilgrastim, we: conducted an ex ante simulation from the payer perspective of the cost-savings of 10–100% conversion from reference to biosimilar pegfilgrastim-bmez using drug price discounting ranging from 10–35%; estimated the budget-neutral expanded access to biosimilar pegfilgrastim-bmez enabled by these cost-savings; and estimated the budget-neutral expanded access to anti-neoplastic treatment with pembrolizumab. The simulations were replicated using fourth quarter 2019 wholesale acquisition cost (WAC) for reference pegfilgrastim and biosimilar pegfilgrastim-bmez in a post facto analysis.

Results: In ASP simulations, cost-savings of using pegfilgrastim-bmez over reference pegfilgrastim in a 20,000 patient panel range from $1.3?M (at 15% price discount) to $3?M (35%) at 10% conversion rate and from $6.4?M to $14.9?M, respectively, at 50% conversion. These savings could provide prophylaxis with pegfilgrastim-bmez to an additional 352 (15% discount) to 1,076 patients (35%) at 10% conversion or 1,764–5,384, respectively, at 50% conversion. Alternatively, savings could be reallocated for anti-neoplastic treatment with pembrolizumab to 3 (15% discount) to 9 (35%) patients at 10% conversion or 19–45, respectively, at 50% conversion. When utilizing WAC, cost-savings range from $4.6?M (10% conversion) to $23.1?M (50%) which could provide pegfilgrastim-bmez to an additional 1,174 (10% conversion) to 5,873 patients (50%).

Conclusions: Prophylaxis with biosimilar pegfilgrastim-bmez increases the value of cancer care by generating significant cost-savings that could be reallocated to provide expanded access to CIN/FN prevention and anti-neoplastic therapy on a budget-neutral basis.