Treatment patterns,complications, and direct medical costs associated with ankylosing spondylitis in Chinese urban patients: a retrospective claims dataset analysis

Aim: To describe treatment pattern, complications, and direct medical costs associated with ankylosing spondylitis (AS) in Chinese urban patients.

Methods: The 2013 China Health Insurance Research Association (CHIRA) urban insurance claims database was used to identify patients with AS. The identified patients were stratified by AS treatments for the comparisons of well established AS-related complications and direct medical costs. Conventional regression analyses adjusted the collected patient baseline characteristics to confirm the impact of treatments on complications and direct medical costs.

Results: Of the identified 1299 patients with AS, 18.0% received non-steroidal anti-inflammatory drugs (NSAID), 11.2% received immunosuppressant, 48.2% received NSAID plus immunosuppressant, 4.6% received biologic agents, and 17.9% received medications without indication for AS. Biologic group was associated with the lowest proportion of AS-related complications (8.3%) that was confirmed by multiple logistic regression analysis (odds ratio = 0.200, p?=?.017). The biologic group was also associated with highest direct medical costs (median: RMB?=?14,539) that were confirmed by the multiple generalized linear model (coefficient = 1.644, p?Conclusions: Biologics were not commonly used for AS in Chinese patients likely due to their high cost. Future studies are needed to confirm the potential long-term clinical benefits associated biologic treatment for AS.     

Investigation of institutional changes in the UK housing market using structural break tests and time-varying parameter models

This paper investigates the effects of institutional changes within the UK housing market in recent decades using structural break tests and time-varying parameter models. This approach is motivated by models of institutional change drawn from the political science literature which focus on the existence of both fast-moving and slow-moving institutional changes and the interactions between them as drivers of the dynamics of asset prices. As a methodological contribution, we use several time-varying parameter models for the first time in investigations of institutional change. Our findings support the existence of both structural breaks and continuous variance in parameters. This contributes to our understanding of the housing market in two respects. Firstly, the dates of structural breaks appear to better match unexpected market shocks rather than remarkable political events, and this supports prior institutional theory. Secondly, assessment of the effect of slow-moving institutional changes shows that people’s biased expectations rather than the economic fundamentals have increasingly played an important role in driving housing prices in the short run although fundamentals continue to drive house prices to converge to their long-run equilibrium.     

组织创新的消极影响:创新研究中的盲点

创新带来的消极影响开始引起学术研究者和管理实践者的关注。从组织创新的概念界定出发,辨析创造力和革新的区别与联系,综述创新在个体层面、团队层面以及组织层面可能产生的消极影响,从前因变量和调节变量两个方面探讨创新产生消极影响的原因,指出未来研究不应忽视创新的消极影响,而应更加科学地解释组织创新的效能。     

Chinese Capitalism and the Maritime Silk Road: A World-Systems Perspective

As China tries to catch up from a semi-peripheral status in the hierarchy of a capitalist world-system, three decades of fast economic growth have recently shown serious signs of capital glut, overproduction and decreasing returns to capital, indicating the beginning of a phase of contraction and stagnation in the long-cycles of capitalist accumulation. The combination of “capital logic” and “territorial logic” in Giovanni Arrighi’s framework gives both the Chinese state and Chinese capital strong incentives and pressure to actively engage in a “spatial fix” by reconfiguring its geographic vision in order to further capital accumulation and expansion on a larger spatial dimension, culminating in the “One Belt, One Road” Initiative, including the Maritime Silk Road Initiative (MSRI). The official promotion of the MSRI hopes to revitalise the historical precedents of the “Silk Road” so that the modern-day hyper-connectivity across Asia, Africa and Europe will facilitate the formation of a China-led reorganised world economy, operating under open and equal participation, possibly leading to common development for all countries involved. However, the nature and impact of such a grandiose initiative, especially its core mission of “connectivity”, is still highly contingent on the hybrid nature of Chinese capitalism in the world-system and how China engages capitalism at the global scale.     

自恋型领导的双面特质对员工组织公民行为的作用机制——一个被调节的中介效应模型

基于51位主管和438名员工的配对问卷调查数据,采用层次回归分析法,探讨了员工的心理授权在自恋型领导与员工组织公民行为间的传导机制,并分析了员工主动性人格的调节作用。结果表明:自恋型领导的双面特质对员工的组织公民行为具有显著影响;员工的心理授权在自恋型领导影响员工组织公民行为的过程中起中介作用;员工的主动性人格调节了自恋型领导通过员工心理授权影响员工组织公民行为的中介作用。     

FDI与OFDI溢出对高技术产业区域创新的门槛效应研究

选取2003-2016年省域高技术产业面板数据,以R&D人员投入为门槛变量,实证分析FDI与OFDI溢出对高技术产业区域创新的非线性影响。得出以下稳健性结论：FDI和OFDI溢出对高技术产业区域创新具有双门槛效应,FDI溢出呈现先升后降的特征,而OFDI溢出则呈现先降后升特征;R&D人员投入、R&D资本积累、城镇化水平有利于高技术产业区域创新,而金融成熟度未产生明显推动作用;政府支持可能对R&D人力投入较高省份产生抑制作用;2003-2016年跨越R&D人员投入中、高门槛的省份在不断增加。     

研发模式对制造业企业创新绩效的影响

将企业研发模式分为自主研发、合作研发和双重研发三种,使用世界银行对中国制造业企业的调查数据,通过倾向得分匹配方法探究不同研发模式对企业创新绩效的作用效果及其在异质性企业中的差异情况。全样本研究结果表明：企业双重研发对创新绩效的激励效果最好,合作研发的激励效果次之,自主研发的激励效果最弱。企业异质性研究结果显示：自主研发对高成长性企业创新绩效的激励效果最显著,合作研发对低成长性企业和小微企业的激励效果最显著;对于无融资约束的企业,双重研发模式是提升创新绩效的最佳选择,但是对有融资约束的企业,其提升效果最弱。     

环境规制科技政策对科技进步与经济增长的影响

基于事件系统理论构建系统性、多层次性和综合性的政策量化分析框架,从政策属性、政策目标和政策工具3个维度对我国1985—2015年制定的198条环境规制科技政策进行量化研究。基于政策评估中的工具理性和价值理性两个层面,从环保科技进步效果和经济增长效应两个维度对环境规制科技政策有效性进行评估。研究发现,我国环境规制科技政策工具及政策工具协同对环保科技进步和经济增长的影响存在显著方向性差异。为此,进一步讨论了我国环境规制科技政策工具及工具协同的政策有效性评估结果,可为我国环境规制科技政策的完善和有效实施提供决策依据。