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21.
In this paper, we develop a computable general equilibrium (CGE) model to shed quantitative light on the implications of a scenario of deeper economic integration between Canada and the United States, where the barriers for foreign direct investment are preferentially eliminated. Our model distinguishes between the activities of domestic and foreign-owned firms at the microeconomic level, both in terms of demand and production characteristics. Overall our findings suggest that further investment liberalization between the two countries will accelerate the shaping of Canada’s industrial structure, as manifested by recent trends.
Yu LanEmail:
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22.
Aims: Peginterferon beta-1a 125?mcg administered subcutaneously every 2 weeks, a new disease-modifying therapy (DMT) for relapsing-remitting multiple sclerosis (RRMS), was approved in January 2015 by the Scottish Medicines Consortium. This study assesses long-term clinical and economic outcomes of peginterferon beta-1a compared with other self-injectable DMTs (interferon beta-1a [22?mcg, 30?mcg, and 44?mcg], interferon beta-1b, and glatiramer acetate 20?mg) in the treatment of RRMS, from the National Health Service and Personal Social Services perspective in Scotland.

Methods: A previously published, validated Markov cohort model was adapted for this analysis. The model estimates changes in patient disability, occurrence of relapses, and other adverse events, and translates them into quality-adjusted life years and costs. Natural history data came from the ADVANCE trial of peginterferon beta-1a, the London Ontario (Canada) database, and a large population-based MS survey in the UK. The comparative efficacy of each DMT vs placebo was obtained from a network meta-analysis. Costs (2015 British Pounds) were obtained from public databases and literature. Clinical and economic outcomes were projected over 30 years and discounted at 3.5% per year.

Results: Over 30 years, peginterferon beta-1a was dominant compared with interferon beta-1a (22, 30, and 44?mcg), and interferon beta-1b, and cost-effective compared with glatiramer acetate 20?mg. Results were most sensitive to variations in each DMT’s efficacy and acquisition costs. Deterministic and probabilistic sensitivity analyses confirmed the robustness of the results.

Limitations: The impact of improved adherence with peginterferon beta-1a on clinical and economic outcomes and the impact of subsequent DMTs after treatment discontinuation were not considered. Oral and infused DMTs were not included as comparators.

Conclusion Long-term treatment with peginterferon beta-1a improves clinical outcomes, while its cost profile makes it either dominant or cost-effective compared with other self-injectable DMTs for the treatment of RRMS in Scotland.  相似文献   
23.
It has been generally assumed that higher levels of scepticism towards advertising invariably lead to higher resistance to advertising appeals. The main purpose of the present research was to examine whether highly sceptical consumers' resistance can be overcome by appeals associated with higher credibility. We tested our hypotheses using message sidedness as an advertising variable that has been associated with higher (two-sided) versus lower (one-sided) credibility. In three experimental studies, we examined more versus less sceptical consumers' responses to two- versus one-sided appeals. We found that two-sided messages are more effective in increasing purchase intentions, through enhanced credibility, but only for consumers who are more sceptical of advertising. Less sceptical consumers trust both messages equally and their purchase intentions are not affected by the type of message. Importantly, we also showed that highly sceptical consumers trust two-sided appeals as much as their less sceptical counterparts. The study contributes to the literature on advertising and persuasion knowledge by showing that advertising scepticism does not elicit a single response tendency, as originally conceptualized. Rather, advertising scepticism is more consistent with the underpinnings of the Persuasion Knowledge Model, in that higher knowledge about persuasion tactics aids consumers to better cope with, and not invariably resist persuasion attempts. We conclude that transparency pays off because it may entice a more sceptical audience and, at the same time, it does not harm less sceptical consumers' trust and purchase intentions.  相似文献   
24.
This study investigates differences in complaining behavior between American and Puerto Rican VCR owners. It is proposed that in Puerto Rico, both cultural values and institutional barriers tend to impose restrictions on complaining behavior that do not exist in the U.S. Hypotheses are developed concerning the impact of cultural differences on: (a) perceptual and attitudinal antecedents to complaining in Day's (1984) model of complaining behavior, (b) the propensity to complain, and (c) the use of public vs. private actions.Results of the data analysis indicate that Puerto Rican VCR owners are less likely to complain than American VCR owners. Also, among complainers, Puerto Ricans were found less likely to take public actions than Americans. Only weak support was obtained for the predicted differences on the antecedent variables to complaining. Implications for marketers and public policy makers are discussed.
Ein interkultureller Vergleich des Beschwerdeverhaltens von Konsumenten: Besitzer von Videokassettenrecordern in den USA und in Puerto Rico
Zusammenfassung Die Studie geht davon aus, daß in Puerto Rico sowohl kulturelle Werthaltungen als auch insitutionelle Barrieren das Beschwerdeverhalten von Konsumenten stärker einschränken als in den USA. Diskutiert werden fünf hinderliche Wertorientierungen, nämlich Passivität, internale Attribution, Abhängigkeit, Vermeidung von Unsicherheit und Fatalismus. Mit institutionellen Barrieren werden Eigenschaften der Marketinginstitutionen gemeint, die direktes Beschwerdeverhalten abwehren. Offensichtlich sind Marketingabteilungen in Puerto Rico weniger empfänglich für kritische Meinungen von Konsumenten als vergleichbare Einrichtungen in den Vereinigten Staaten.Bei der Hypothesenbildung werden die Einflußfaktoren auf das Beschwerdeverhalten nach dem Modell von Day(1984) benutzt, die mit kulturellen Unterschieden variieren dürften. Diese Einflußfaktoren sind(a) die wahrgenommenen Kosten der Beschwerde, (b) die subjektiv empfundene Wahrscheinlichkeit, daß die Beschwerde Erfolg haben wird, und (c) die Einstellung gegenüber dem Beschweren als Verhaltensweise. Die empirischen Ergebnisse zeigen bei Puertoricanern tatsächlich eine geringere Tendenz zum Beschwerdeverhalten als bei Amerikanern, wenn auch im einzelnen nicht alle Hypothesen durch die Daten gestützt werden. Der Beitrag diskutiert Schlußfolgerungen sowohl für das Marketing wie auch für die Verbraucherpolitik. Die Anbieter sollten die Empfänglichkeit für Konsumentenbeschwerden in Puerto Rico erhöhen. Kommunikationspolitische Maßnahmen der Hersteller von Videokassettenrecordern sollten den Konsumenten in Puerto Rico deutlich machen, daß ihnen die Zufriedenheit der Kunden ein echtes Anliegen ist.Andererseits sollte die staatliche Einrichtung für Konsumentenangelegenheiten in Puerto Rico Erziehungsprogramme entwickeln mit dem Ziel, Konsumenten deutlich zu machen, daß Beschwerdeführung bei Produktmängeln ein angemessenes und wünschenswertes Verhalten ist. Ebenso sollte diese Einrichtung prüfen, ob neue gesetzgeberische Maßnahmen zum Verbraucherschutz notwendig sind.


Sigfredo A. Hernandez and William Strahle are Assistant Professors of Marketing and Robert C. Sorensen is Professor of Marketing at Rider College, Lawrenceville Rd, Lawrenceville, NJ 08648, USA. Hector L. Garcia is Assistant Professor of Social Sciences at Universidad del Turabo, P.O. Box 3030, University Station, Gurabo, PR 00658, USA.  相似文献   
25.
This paper measures TFP growth of Telefonica del Peru, and based on this growth rate computes a telecommunications X-factor or offset. More broadly the paper analyses the problem of updating an X-factor under existing price cap regulation. A revised offset must account for the possible restructuring of service offerings resulting from improved efficiencies in response to price cap incentives. Our updating framework focuses on efficiency criteria, and based on economic principles emphasizes the continuity between prior and continuing standards. In the case of Peru, based on annual average TFP growth of 1.66%, the X-factor is computed to be 4.06% per year. An erratum to this article can be found at  相似文献   
26.
We study properties of the mean residual life functions of finite mixtures. Specifically, we study ordering properties, monotonicity and the limiting behaviour. We show, under some mild conditions, that the limiting behaviour is similar to that of the strongest member (in the mean residual life order) of the mixture. We also consider the case of negative mixtures (i.e., mixtures with some negative coefficients) which is applied to study the behaviour of the mean residual life of order statistics and coherent systems with possibly dependent components. Partially Supported by Ministerio de Ciencia y Tecnologí a under grant BFM2003-02947 and Fundación Séneca under grant 00698/PI/04.  相似文献   
27.
This paper analyses environmental reporting practices found in the annual reports published by 51 large companies operating in Spain, with the aim of determining which factors in the firms analysed – belonging to ecologically sensitive sectors – explain the quantity and characteristics of the environmental information published and its evolution. Moreover, the paper takes into account the implementation of the Spanish compulsory accounting standard of 25 March 2002 and its impact on the environmental reporting behaviour. The results of the content analysis for the period 2001–02 show a significant increase in the environmental information compared with the 1992–94 period. For the first year in which the environmental accounting standard was in force (2002), the results show a high percentage of environmental disclosures in the notes to the annual accounts, although the degree and level of disclosures is very heterogeneous, in both form as well as quantity and quality. Copyright © 2006 John Wiley & Sons, Ltd and ERP Environment.  相似文献   
28.
This study examines differences in returns to literacy skills on earnings of black and white men and women. Literacy skill is a composite measure of three scales: reading comprehension, document literacy (the ability to locate and use information in, say, tables and graphs), and mathematics proficiency. Using data from the National Adult Literacy Survey (NALS), we estimate earnings determination models separately for each racial/gender group. Our findings show that the effect of literacy on earnings varies by race and gender. Literacy skills favorably rewarded black men relative to black women and white men and women, net of education and other relevant variables. More importantly, literacy completely explained the effect of a high school diploma and some college on earnings of black men. We conclude that the economic importance of literacy skills is particularly salient for less-educated black men.  相似文献   
29.
This article focuses on the rapid development of the “modernizing wholesale” channel, with a study of guava traders and farmers in Mexico. This adds to a literature on modernization of food markets that has focused primarily on exports, supermarkets, and large processors and addressed less wholesale in general and rarely modernizing wholesale per se. We find that participation in the modernizing wholesale channel, relative to the traditional broker channel, requires greater land, regional, and nonland assets, as well as confers a premium controlling for quality, and spurs employment in harvesting and handling locally.  相似文献   
30.
The importance of credit access to improve economic opportunities in developing markets is well established in the literature. However, there exists a strong need to mitigate adverse selection problems in microlending. A risk scoring model that more accurately predicts the likelihood of repayment of potential borrowers can help address this market imperfection and to benefit both lenders and borrowers. This paper compares the performance of nonparametric versus semiparametric and traditional parametric risk scoring models based on default probabilities. We show the advantages of relying on less structured, data-driven methods for risk scoring using both simulated data and data from credit loans granted to small and microenterprises in rural Peru. The estimation results indicate that nonparametric methods lead to a better evaluation of credit worthiness and can help prevent including potential “bad” borrowers and excluding “good” borrowers from sensitive microcredit markets.  相似文献   
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