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Linking together two optimal control theory problems through Bellman's equation we derive closed form solutions for an extractive industry when a shift in the demand curve is perfectly foreseen. Monopoly and competition are compared. 相似文献
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S. M. Miller 《International journal of urban and regional research》1977,1(1-3):126-131
Une stratégie qui se dit neuve pour affronter la crise économique en cours semble avoir provoqué un nombre ? effets négatifs aux Etats-Unis (et ailleurs). Un taux de chǒmage élevé, une inégalité croissante, ainsi que des services publics qui se détériorent, sont les résultats ? un effort de re-capitalisation du capitalisme achevé par la promotion ? investissements et de profits privés. Ceci est le cadre pour un développement possible ? agitation ouvrière et de mouvements sociaux urbains. Les perspectives limités de beaucoup de mouvements sociaux urbains américains ne veulent nécessairement pas dire qu'ils manquent de signification. L'époque de la réforme structurelle doit ětre gagnée; elle est rarement déja acquise. 相似文献
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Ralph P. Insinga David J. Vanness Josephine L. Feliciano Kristel Vandormael Sory Traore Thomas Burke 《Journal of medical economics》2013,16(12):1191-1205
AbstractAims: To describe cost-effectiveness of pembrolizumab plus platinum and pemetrexed chemotherapy in metastatic, non-squamous, NSCLC patients in the US.Materials and methods: A model is developed utilizing partitioned survival analysis to estimate the cost-effectiveness of KEYNOTE-189 trial comparators pembrolizumab?+?chemotherapy (carboplatin/cisplatin?+?pemetrexed) vs chemotherapy alone. Clinical efficacy, treatment utilization, health utility, and safety data are derived from the trial and projected over 20 years. For extrapolating survival beyond the trial, a novel SEER population-data approach is applied (primary analysis), with separate estimation via traditional parametric extrapolation methods. Costs for drugs and non-drug disease management are also incorporated. Based on an indirect treatment comparison, cost-effectiveness of pembrolizumab?+?chemotherapy vs pembrolizumab monotherapy is evaluated for patients with programmed death-ligand 1 (PD-L1)?≥?50%.Results: In the full non-squamous population, pembrolizumab?+?chemotherapy is projected to increase life expectancy by 2.04 years vs chemotherapy (3.96 vs 1.92), for an approximate doubling of life years. Resultant incremental cost-effectiveness ratios (ICERs) are $104,823/QALY and $87,242/life year. In patients with PD-L1?≥?50% and 1–49%, life expectancy is more than doubled (4.53 vs 1.88 years) and (4.87 vs 2.01 years), with a 32% (2.60 vs 1.97 years) increase in PD-L1?<?1% patients. Corresponding incremental costs/quality-adjusted life year (QALY) are $103,402, $66,837, and $183,529 for PD-L1?≥?50%, 1–49%, and <1% groups, respectively. Versus pembrolizumab monotherapy in PD-L1?≥?50% patients, representing current standard of care, pembrolizumab?+?chemotherapy increases life expectancy by 65% (4.53 vs 2.74 years) at an ICER of $147,365/QALY.Limitations and conclusions: The addition of pembrolizumab to chemotherapy is projected to extend life expectancy to a point not previously seen in previously untreated metastatic non-squamous NSCLC. Although ICERs vary by sub-group and comparator, results suggest pembrolizumab?+?chemotherapy yields ICERs near, or in most cases, well below a 3-times US per capita GDP threshold of $180,000/QALY, and may be a cost-effective first-line treatment for metastatic non-squamous NSCLC patients. 相似文献
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Patrick Bajari Phoebe Chan Dirk Krueger Daniel Miller 《International Economic Review》2013,54(2):409-442
Using data from the PSID, we estimate a dynamic model of housing demand with nonconvex adjustment costs, credit constraints, and uncertainty about income and home prices. We simulate how consumer behavior responds to house price and income declines as well as tightening credit. In response to a negative home price shock, households early in the life cycle climb the housing ladder more quickly and invest more in housing assets due to the lower price. With a concurrent negative income shock, however, housing demand falls among young and middle aged households who stay in smaller homes rather than to trade up. 相似文献
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Edward W. Frees F.S.A. Ph.D. Robert B. Miller Ph.D. 《North American actuarial journal : NAAJ》2013,17(2):53-70
Abstract Actuaries, like other business professionals, communicate quantitative ideas graphically. Because the process of reading, or decoding, graphs is more complex than reading text, graphs are vulnerable to abuse. To underscore this vulnerability, we give several examples of commonly encountered graphs that mislead and hide information. To help creators design more effective graphs and to help viewers recognize misleading graphs, this article summarizes guidelines for designing graphs that show important numerical information. When designing graphs, creators should:
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(1) Avoid chartjunk
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(2) Use small multiples to promote comparisons and assess change
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(3) Use complex graphs to portray complex patterns
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(4) Relate graph size to information content
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(5) Use graphical forms that promote comparisons
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(6) Integrate graphs and text
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(7) Demonstrate an important message
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(8) Know the audience.
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Karen Miller 《公共资金与管理》2013,33(1):43-50
The UK government has committed itself to improving the representation of women in public service and has introduced a number of legislative measures, policies and development programmes to do this. In 2006, the government enacted a regulatory duty, placed on public sector organizations, to mainstream gender equality in policy and service delivery. This article explores the extent to which this duty could promote gender equality and makes some recommendations for improving the representation of women. 相似文献