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101.
International Advances in Economic Research - The share of world trade attributed to intra-firm trade is large and fast-growing. This paper offers new information on the welfare outcome of these... 相似文献
102.
Abdalla Aly Courtney Johnson Shuo Yang Sumati Rao Arif Hussain 《Journal of medical economics》2019,22(7):662-670
Aims: Medicare patients with metastatic or surgically unresectable urothelial carcinoma (mUC) often receive platinum-based chemotherapy as first line of therapy (LOT), but invariably progress, requiring additional LOTs and healthcare resource use (HCRU). To better understand the evolving mUC treatment landscape, the economic burden of chemotherapy-based mUC treatments among US Medicare patients was estimated.Methods: Newly diagnosed Medicare patients with mUC were identified from the Surveillance, Epidemiology, and End Results (SEER)-Medicare database. Patients were followed from diagnosis to death, disenrollment, or end of study to characterize LOTs (first [LOT1], second [LOT2], and third or greater [LOT3+]). Kaplan-Meier methods were used to estimate overall survival (OS) by LOT. HCRU and mean costs were reported over the follow-up period, LOT duration, and maximum LOT received.Results: Among 1,873 eligible patients with mUC (median age?=?77?years; median follow-up?=?7.5?months), 1,035 (55%) received no chemotherapy. Among chemotherapy-treated patients, 61% had LOT1 only, 25% had LOT1 and LOT2 only, and 14% had LOT3+. Median OS was 8.1?months, range was 4.3 (untreated) to 29.8 (LOT3+) months. HCRU frequency increased with additional LOTs. Mean cumulative per-patient cost was $82,912 for all patients, increasing with additional LOTs (untreated?=?$57,207; LOT1?=?$99,213; LOT2?=?$125,190; LOT3+?=?$163,884). Mean per patient per month cost was $18,827 for all patients, decreasing with increasing number of LOTs received (untreated?=?$27,211; LOT1?=?$9,601; LOT2?=?$7,325; LOT3+?=?$6,017).Limitations: Potential for treatment misclassification when using the algorithm defining LOTs and non-generalizability of results to younger patients.Conclusions: Over 50% of Medicare patients with mUC received no chemotherapy. Among chemotherapy-treated patients, most received only one LOT. Additional LOTs led to higher mean costs and HCRU, but as patients were followed longer, monthly costs decreased. As treatments evolve to include immuno-oncology agents, these findings provide a clinically relevant economic benchmark for mUC treatment across different traditional LOTs. 相似文献
103.
在缺乏卖空机制的环境下,可转债相对价值的实现将主要来源于转债与股票之间的资产替换。尤其是在杠杆放大的资产替代策略下,可转债投资的盈利模式将出现根本性变化,股票价格的波动成为影响策略应用效果的最重要因素。本从对冲套利的角度,通过对等额和杠杆放大资产替换策略的模拟与分析,就资产替换策略的应用环境、杠杆选择与实证效果等问题进行了较为详尽的研究。 相似文献
104.
“长三角”旅游服务质量预警机制建立的研究 总被引:1,自引:0,他引:1
打造中国旅游的“金三角”,苏、浙、沪三地必须实现旅游资源的整合。而建立有效的旅游服务质量预警机制是实现旅游资源整合的基础。 相似文献
105.
本文设计了一种新型的艺术彩灯控制系统,该系统使用单片机作为控制核心,采用了PWM脉宽调制技术。在系统硬件电路中增加了过零检测,利用三极管电路控制彩灯颜色的变化和组合。改进了传统艺术彩灯制作工艺要求严格,色彩变化单一的缺点。通过实验,该系统运行稳定,易于扩展。 相似文献
106.
创业不仅是经济持续增长的动力,也是新常态下我国经济增长方式转变的重要源泉。从个人社交指数和风险倾向着手,分析其对个人创业的影响,同时考虑政府干预、市场成熟度和产权保护水平对社交指数和风险倾向与创业之间的调节作用,并将个人特质和区域因素作为控制变量纳入分析框架,运用CGSS 3年的数据进行实证分析。结果表明,个人社交指数对创业具有正向影响,个人风险倾向对创业的影响存在区域异质性。在农村地区,个人风险倾向对创业活动具有正向影响,即风险倾向越高,创业概率越大;而在城镇,个人风险倾向对创业的影响为负。在制度环境层面,政府干预和市场成熟度对创业具有负向影响,产权保护水平与创业之间存在“倒U型”关系,制度环境对社交指数与创业之间的关系具有调节作用,较高政府干预力度和较低市场成熟度使社交指数与创业负相关,而产权保护水平的调节作用则较弱;制度环境对风险倾向的调节作用较弱。 相似文献
107.
Purpose: The purpose of this study is to examine whether buyers perceive different electronic marketplaces (EMs) as distinct types of procurement platforms. More specifically, it empirically investigates to what extent professional buyers expect different benefits from different EM types and perceive different barriers associated with their usage. Methodology: A Web-based survey of purchasing professionals in the United States was conducted with 359 responses received. A multivariate analysis of variance (MANOVA) was performed to determine if there are significant differences between EM types with respect to expected benefits (market aggregation and inter-firm collaboration) and perceived barriers (financial risks and trust barriers). Findings: The results show buyers' expectations of benefits differ significantly between public EMs (i.e., third-party exchanges and industry-sponsored marketplaces) and private EMs (i.e., private trading networks), and between neutral EMs (i.e., third-party exchanges) and biased EMs (i.e., private trading networks and industry-sponsored marketplaces). Likewise, their perception of barriers differs significantly between public and private EMs. Research limitations/implications: The research confirmed empirically that EMs are a distinct platform for business-to-business procurement. Nevertheless, by examining EMs from business buyers' perspective, this study necessarily limits itself to purchasing-related issues. Practical implications: By providing insights into buyers' perceptions, our findings can help managers focus their promotional efforts aimed at potential firms that would like to use EM for procurement by emphasizing specific benefits or addressing specific perceived barriers based on the type of EM they manage. Originality/value: This study fills a void in academic literature on EMs that currently contains few empirical studies with respect to EM types. Its main contribution is in establishing empirically that EMs do not constitute a single, homogeneous marketspace but are instead comprised of distinct types that offer users specific benefits and expose them to certain risks. 相似文献
108.
Stanley E. Griffis Shashank Rao Thomas J. Goldsby Tarikere T. Niranjan 《Journal of Operations Management》2012
Pressure continues to build on the operations management function to facilitate system and firm level benefits. In the online marketplace, one area of growing interest is that of product returns. Though commonly viewed as a cost center from an operations perspective, operations’ actions have the potential to strongly influence future customer buying behavior in several ways. Using an archival database of actual purchase and returns history provided by a moderately sized online retailer, this study examines the relationship between a customer's experience of product returns, and subsequent shopping behavior. Employing transaction cost, consumer risk, and procedural justice theories, we demonstrate that the returns management process, rather than being regarded as an afterthought to the production and deployment of goods, can significantly and positively influence repurchase behavior. Additionally, we provide evidence that certain customers should be considered for prioritization in the returns process. We suggest ways through which operations managers can take care in discharging their responsibilities in this area – to make returns processing more than simply a “necessary cost of doing business” rather, using it to their advantage in engendering repeat and increased purchase behavior. 相似文献
109.
Anusorn Singhapakdi Janet K. Marta Kumar C. Rallapalli C. P. Rao 《Journal of Business Ethics》2000,27(4):305-319
This study examines the influence of religiousness on different components of marketing professionals' ethical decision making: personal moral philosophies, perceived ethical problem, and ethical intentions. The data are from a national survey of the American Marketing Associations' professional members. The results generally indicate that the religiousness of a marketer can partially explain his or her perception of an ethical problem and behavioral intentions. Results also suggest that the religiousness significantly influences the personal moral philosophies of marketers. 相似文献
110.
营业税改征增值税的税制改革一直是中国近年来财税体制改革领域的热点问题,其涉及改革范围、政府间财政关系的调整等诸多方面,堪称中国“十二五”时期财税体制改革的“牛鼻子”。文章以上海市为例就“营改增”税制改革从系统循环角度出发,分析此次改革对上海市地方财政收入规模结构的影响,从而对其地方财政支出规模结构的影响,最终影响到其地方经济的发展,并在这个基础上又对其地方财政收入开始新的一轮的循环影响。由于“营改增”税制改革现已在全国范围内开展,为顺利推进此次改革.保持其地方政府财力不变.文章也提出了一些改革的相应配套措施. 相似文献