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91.
The member countries of the World Health Organization have endorsed its Global Strategy on Diet, Physical Activity, and Health. We assess the potential consumption impacts of these norms in the United States, France, and the United Kingdom using a mathematical programming approach. We find that adherence would involve large reductions in the consumption of fats and oils accompanying large rises in the consumption of fruits, vegetables, and cereal. Further, in the United Kingdom and the United States, but not France, sugar intakes would have to shrink considerably. Focusing on sub-populations within each country, we find that the least educated, not necessarily the poorest, would have to bear the highest burden of adjustment.  相似文献   
92.
Vertical product differentiation and two-sided markets   总被引:1,自引:0,他引:1  
We model platform competition in a market where products are characterized by cross network externalities. Consumers differ in their valuation of these externalities. Although the exogenous set-up is entirely symmetric, we show that platform competition induces a vertical differentiation structure that allows for the co-existence of asymmetric platforms in equilibrium. We establish this result in two set-ups: in the first one platforms commit to prices, in the second one they commit to network sizes.  相似文献   
93.
Objective: Philadelphia chromosome negative [Ph(?)] relapsed or refractory (R/R) B-precursor acute lymphoblastic leukemia (ALL) is an extremely rare condition requiring intensive treatment. This retrospective chart review aimed to quantify hospitalizations and reimbursement in this patient population in France.

Methods: Patients aged ≥18 years and with at least one hospitalization for Ph(?) R/R B-precursor ALL were included in the study. They were relapsed with first remission lasting <12 months, relapsed after first salvage therapy, relapsed any time after hematopoietic stem cell transplant (HSCT), or were refractory to initial or salvage therapy. Data were collected from the index date (first diagnosis of R/R ALL) until death or loss to follow-up. The chemotherapy period was defined as the first chemotherapy date after the index date to the earliest of death, loss to follow-up, last chemotherapy dose plus 30 days, or initiation of HSCT. The primary outcome was the percentage of time hospitalized during the chemotherapy period.

Results: Thirty-three patients were included, with a mean age of 49 years. The mean proportion of time spent in the hospital during the chemotherapy period was 46% (95% CI =34–57%). Patients had a mean of 2.2 (SD =1.5) inpatient hospitalizations and the mean length of stay per hospitalization was 16.8 (SD =14.8) days. During the chemotherapy period, the mean amount reimbursed per hospitalization was €31 067 (SD = €4850) and the total hospitalization reimbursement per patient was €68 344. From the index date to death, excluding HSCT, the total reimbursement per patient was €108 873.

Limitations: The sample size was small, although this was expected given the rarity of the patient population.

Conclusions: Adults with Ph(?) R/R B-precursor ALL had repeated and prolonged hospitalizations during salvage chemotherapy. Approximately half the follow-up period was spent in the hospital, and this time was associated with high economic burden in France.  相似文献   
94.
This paper develops a modelling framework that links GEMINI-E3, a multi-regional, multi-sectoral computable general equilibrium model with a cost-benefit analysis approach at local level using geographical information system tools to assess the physical and economic consequences of sea-level rise (SLR) in the twenty first century. A set of future scenarios is developed spanning the uncertainties related to global warming, the parameters of semi-empirical SLR estimates, and coastal developments (cropland, urban areas and population). The importance of incorporating uncertainties regarding coastal development is highlighted. The simulation results suggest that the potential development of future coastal areas is a greater source of uncertainty than the parameters of SLR itself in terms of the economic consequences of SLR. At global level, the economic impact of SLR could be significant when loss of productive land along with loss of capital and forced displacement of populations are considered. Furthermore, highly urbanised and densely populated coastal areas of South East Asia, Australia and New Zealand are likely to suffer significantly if no protective measures are taken. Hence, it is suggested that coastal areas needs to be protected to ameliorate the overall welfare cost across various regions.  相似文献   
95.
The slow and endogenous twist of economic macro-structure makes up an important evolutionary feature of capitalist economies, and may be at the root of structural crisis. In this line, a Goodwinian growth model with increasing returns and profit-sharing that tries to picture a simple scenario of the seventies crisis is considered. It is shown that the exhaustion of the Kaldor-Verdoorn “productivity law” can entail, in a nonlinear framework, a “catastrophic” bifurcation from a “high” to a “low” growth path. Slow/fast dynamical systems then allow one to formalize a multiple time-scales dynamics where the growth path is shaped by the structural framework in which it takes place, but has also a long -un feedback. Structural change and crisis appear as long term and endogenous outcomes.  相似文献   
96.
The article discusses the development of agricultural cooperatives in Kyrgyzstan from an entrepreneurial ecosystem (EE) perspective. Agricultural development priorities explain cooperatives’ importance in Kyrgyz government's policies, but cooperatives still fail at countering the challenges of the smallholder economy. Considering agricultural cooperatives as a form of rural entrepreneurship, this paper aims to contribute to the discussion of the factors that support cooperatives in developing countries adapting the EE framework to cooperative entrepreneurship. Using a content analysis method, we analysed and coded textual data from documentary and archival publications on the agricultural cooperatives in Kyrgyzstan published by the government, cooperatives and their unions and the reports of international organizations. We identify five main dimensions of the cooperative entrepreneurial ecosystem for cooperatives: (1) policy and regulatory framework; (2) education and skills; (3) market environment; (4) culture; (5) networks. We found that even if the overall structure of cooperatives’ EE can be comparable to conventional enterprises, its sub-elements significantly differ for cooperative enterprises. Despite its exploratory character and single-case research design, this article contributes to the theoretical discussion on cooperative entrepreneurial ecosystems in post-socialist developing contexts and offers a framework of analysis for cooperative development policies and practices.  相似文献   
97.
Subjective well-being (SWB) data are increasingly used to perform welfare analysis. Interpreted as “experienced utility”, it has recently been compared to “decision utility” using small-scale experiments most often based on stated preferences. We transpose this comparison to the framework of non-experimental and large-scale data commonly used for policy analysis, focusing on the income–leisure domain where redistributive policies operate. Using the British Household Panel Survey, we suggest a “deviation” measure, which is simply the difference between actual working hours and SWB-maximizing hours. We show that about three-quarters of individuals make decisions that are not inconsistent with maximizing their SWB. We discuss the potential channels that explain the lack of optimization when deviations are significantly large. We find proxies for a number of individual and external constraints, and show that constraints alone can explain more than half of the deviations. In our context, deviations partly reflect the inability of the revealed preference approach to account for labor market rigidities, so the actual and SWB-maximizing hours should be used in a complementary manner. The suggested approach based on our deviation metric could help identify labor market frictions.  相似文献   
98.
The 2009 Malaysian Government Transformation Programme (GTP) could be useful as a model for reform given its positive impact on improving public services in targeted key result areas. This paper assesses the GTP's approach in the context of the wider debate on whether reforms should be based on best practices or whether they should be diagnostic or problem-solving in approach. The GTP's success was largely the result of blending both approaches. The GTP experience in Malaysia provides a number of insights and lessons for delivering intelligent reforms quickly and effectively.  相似文献   
99.
Universal service and public access in the networked society   总被引:1,自引:0,他引:1  
Concern about access to the new services and facilities emerging from the technologically dynamic telecommunications industry and its ‘convergence’ with broadcasting and information technology has resulted in calls for a reconsideration of the nature and scope of Universal Service Obligations (USOs) so that they are more adequate and relevant in an era of technological acceleration towards a networked information society. This paper assesses approaches to upgrading USOs and to developing policies for public access to the networked society undertaken thus far in various OECD countries, and proposes frameworks for conducting the tasks in a systematic manner.  相似文献   
100.
Let \(S^{F}\) be a ?-martingale representing the price of a primitive asset in an incomplete market framework. We present easily verifiable conditions on the model coefficients which guarantee the completeness of the market in which in addition to the primitive asset, one may also trade a derivative contract \(S^{B}\). Both \(S^{F}\) and \(S^{B}\) are defined in terms of the solution \(X\) to a two-dimensional stochastic differential equation: \(S^{F}_{t} = f(X_{t})\) and \(S^{B}_{t}:=\mathbb{E}[g(X_{1}) | \mathcal{F}_{t}]\). From a purely mathematical point of view, we prove that every local martingale under ? can be represented as a stochastic integral with respect to the ?-martingale \(S :=(S^{F}, S^{B})\). Notably, in contrast to recent results on the endogenous completeness of equilibria markets, our conditions allow the Jacobian matrix of \((f,g)\) to be singular everywhere on \(\mathbb{R}^{2}\). Hence they cover as a special case the prominent example of a stochastic volatility model being completed with a European call (or put) option.  相似文献   
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