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21.
This article provides a comparative analysis of changes in numerical and functional labour flexibility in the French and the UK food processing industry. Based upon case study data, it explores the interaction between competitive pressures and institutional and regulatory structures and their impact on workplace practices. The findings indicate that, faced with a similar competitive environment, firms in both countries have sought to increase labour flexibility. However, the predominant forms of flexibility vary across the two countries, partly reflecting the characteristics of national labour market institutions. Numerical flexibility dominates in the UK, with high levels of paid overtime and temporary agency work. In contrast, French workplaces rely more on internal functional flexibility while also achieving numerical flexibility through seasonal variations in work schedules and a wide range of short‐term employment contracts.  相似文献   
22.
This paper investigates the effects of largest-shareholder ownership concentration, foreign ownership, and audit quality on the amount of firm-specific information incorporated into share prices, as measured by stock price synchronicity, of Chinese-listed firms over the 1996–2003 period. We show that synchronicity is a concave function of ownership by the largest shareholder with its maximum at an approximate 50% level. Further, we find that synchronicity is higher when the largest shareholder is government related. We also find that foreign ownership and auditor quality are inversely associated with synchronicity. Finally, we show that the amount of earnings information reflected in stock returns is lower for firms with high synchronicity.  相似文献   
23.
This paper explores hotel employees’ perception on work–life balance issues. In-depth interviews and self-administered questionnaires were used to collect the data. Factor analysis discovered seven factors: (1) enough time-off from work; (2) workplace support on work–life balance; (3) allegiance to work; (4) flexibility on work schedule; (5) life orientation; (6) voluntary reduction of contracted hours to cater for personal needs; and (7) upkeep the work and career—the determinants perceived by employees to attain “better” work–life balance in the dynamic hotel environment. Adopting an employee-centric and integrative approach are the critical success factors for implementation of a work–life balance program.  相似文献   
24.
Objective: To describe the setting, duration, and costs of induction and consolidation chemotherapy for adults with newly-diagnosed acute myeloid leukemia (AML), who are candidates for standard induction chemotherapy, in the US.

Methods: Adults newly-diagnosed with AML who received standard induction chemotherapy in an inpatient setting were identified from the Truven Health Analytics MarketScan (2006–2015) and SEER-Medicare (2007–2011) databases. Patients were observed from induction therapy start to the first of hematopoietic stem cell transplant, 180 days after induction discharge, health plan enrollment/data availability end, or death. Induction and consolidation chemotherapy were identified using Diagnosis-Related Group codes (chemotherapy with acute leukemia) or procedure codes for AML chemotherapy administration. AML treatment episode setting (inpatient or outpatient), duration, and costs (2015 USD, payers’ perspective) were described for commercially insured patients and Medicare beneficiaries.

Results: In total, 459 commercially insured patients and 563 Medicare beneficiaries (mean age?=?54 and 66 years; 53% and 54% male; respectively) were identified. For induction therapy, mean costs were $145,189 for commercially insured patients and $85,734 for Medicare beneficiaries, and median inpatient duration was 31 days (both). Following induction, 64% of commercially insured patients and 53% of Medicare beneficiaries had ≥1 consolidation cycle; 75% and 65% of consolidation cycles were in an inpatient setting, respectively. For consolidation cycles, in the inpatient setting, mean costs were $28,137 for commercially insured patients and $28,843 for Medicare beneficiaries, median cycle duration was 6 days (both); in the outpatient setting, mean costs were $11,271 for commercially insured patients and $5,803 Medicare beneficiaries, median duration was 5 days (both).

Limitations: Granular information on chemotherapy type administered was unavailable.

Conclusions: This is the first exploratory study providing a complete picture of recent AML treatment patterns and management costs among commercially insured patients and Medicare beneficiaries. There is substantial heterogeneity in the management and costs of AML.  相似文献   
25.
Objective: To evaluate the cost-effectiveness of second-line nilotinib vs dasatinib among patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (Ph+?CML-CP) who are resistant or intolerant to imatinib, from a US third-party perspective.

Methods: A lifetime partitioned survival model was developed to compare the costs and effectiveness of nilotinib vs dasatinib, which included four health states: CP on treatment, CP post-discontinuation, progressive disease (accelerated phase [AP] or blast crisis [BC]), and death. Time on treatment, progression-free survival, and overall survival of nilotinib and dasatinib were estimated using real-world comparative effectiveness data. Parametric survival models were used to extrapolate outcomes beyond the study period. Drug treatment costs, medical costs, and adverse event costs were obtained from the literature and publicly available databases. Utilities of health states were derived from the literature. Incremental cost-effectiveness ratios, including incremental cost per life-year (LY) gained and incremental cost per quality-adjusted life-year (QALY) gained, were estimated comparing nilotinib and dasatinib. Deterministic sensitivity analyses were performed by varying patient characteristics, cost, and utility inputs.

Results: Over a lifetime horizon, nilotinib-treated patients were associated with 11.7 LYs, 9.1 QALYs, and a total cost of $1,409,466, while dasatinib-treated patients were associated with 9.5 LYs, 7.3 QALYs, and a total cost of $1,422,122. In comparison with dasatinib, nilotinib was associated with better health outcomes (by 2.2 LYs and 1.9 QALYs) and lower total costs (by $12,655). Deterministic sensitivity analysis results showed consistent findings in most scenarios.

Limitations: In the absence of long-term real-world data, the lifetime projection could not be validated.

Conclusions: Compared with dasatinib, second-line nilotinib was associated with better life expectancy, better quality-of-life, and lower costs among patients with Ph+?CML-CP who were resistant or intolerant to imatinib.  相似文献   
26.
27.
A bstract    Fisher's virulent positions on such themes as "race degeneration", the necessity of sterilization measures for certain categories of the American population, and his urgent call for the control of the genetic quality of new immigrants are hardly consistent with the opalescent subtlety of academic disputes over the nature of capital and interest. Although Fisher repeats it often: in his work, this question of the nature of capital and interest is directly linked to eugenic assumptions and analysis. This second body of Fisherian work illuminates the strong epistemological and theoretical references in Fisher's work as an economist. This paper addresses this question through three major themes: the constant denunciation of a «racial decay>> of the American population and its corollary: the project of setting up a «scientific humaniculture>>; the plea against the eugenic effects of World War I, and the then haunting question of the closing of the «Golden Door>>.  相似文献   
28.
This paper is based on empirical research conducted with directors in large UK organizations, first in 1987–89, and again in 1998–2000. While the time frame has changed, the focus of the inquiry has remained constant – how do you 'run' a large organization – and data gathered reflect significant changes over time as to how the question is answered. This paper addresses one particular aspect of this complex material: the changing power of practitioner and academic explanations across the decade, highlighted by comparing and contrasting this data and its analysis over time.
The paper illustrates a surprising degree of consistency (in contrast to 1987–89 findings) in practitioners' contemporary explanations of their organizing: all talk of strategic focus, shareholder value and corporate governance, phrases previously never mentioned. This reflects a variety of changes across the decade, including an important concentration of power amongst investors. As well as the methodological implications of 'repeating' this study, the changing power of academics' explanations 'on' organization is also discussed as conceptual frameworks gain and lose their resonance with the times. The paper concludes that sensemaking (Weick, 1995) offers the most appropriate perspective by which such shifts in the power of explanations may best be appreciated.  相似文献   
29.
Though the USSR officially touted equal opportunity for women, women in Russia earned only 70 percent of men's wages. The combination of women's dual roles in society and inadequate investment by the Soviets in household time-saving devices are often cited as reasons for a lack of commitment and advancement in the labor market. With the recent transition towards a market economy, there is reason to think these effects may be changing. As women become increasingly freer to substitute between formal-sector and household work, the relative importance of commitment in explaining the gender-wage disparity may have diminished. Using data from the Russian Longitudinal Monitoring Survey, this study hopes to shed light on whether differences in time allocated towards household production are capable of affecting wages.  相似文献   
30.
A survey of 38 airports in British Columbia, Alberta and Saskatchewan, Canada, is used to document and explore differences in use of Airport Wildlife Management Plans; common wildlife attractants; wildlife countermeasure usage and outcomes; and animal strike record keeping systems. Hazardous activities and practices for managing waste and agricultural crops commonly occurred within 8 km of airports, but also occasionally airside or groundside. Maintaining long grass was the most routinely used countermeasure, but there are conflicting responses regarding the most appropriate grass length to deter wildlife. Removal of diverse habitat had the highest success ranking among listed countermeasures. Over 75% of airports kept strike records, but less than 7% used them to measure the outcomes of countermeasure implementation.  相似文献   
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