Healthcare professionals’ perceptions of risk in the context of genetic testing for the prediction of chronic disease: a qualitative metasynthesis

Advances in genomic technologies and a growing trend towards stratified and preventive approaches to medicine mean that increasing numbers of individuals may have access to information about their genetic makeup, and their risk of developing diseases. This is likely to impact on healthcare professionals involved in the delivery of genetic tests, or in supporting patients who are affected by a disease with a genetic risk factor. It is therefore important to understand healthcare professionals’ perceptions about providing these services, and how they feel about communicating information about genetic risk to patients. This paper provides a systematic review and metasynthesis of qualitative research exploring healthcare professionals’ perceptions of genetic risk in the context of predictive genetic testing for chronic disease. Healthcare professionals expressed a range of reservations about the utility of predictive testing in this context. Professionals judged patients’ understanding of risk information to be limited and subject to bias and a range of sociocultural influences. Concerns about the psychosocial impact of genetic risk information were frequently cited, both in relation to individual patients and the wider impact on their families and communities. The need for provision of multidisciplinary support was described. The concept of responsibility was also an important theme. Healthcare professionals recognized the responsibility that accompanies risk knowledge, and that ultimately this responsibility lies with the patient, not the provider. Our analysis suggests that professionals’ evaluation of the utility of predictive genetic testing is influenced not only by resource deficits, but may also be interpreted as a response to challenging ethical and social issues associated with genetic risk, that are not well aligned with current medical practice.     

Risk mitigation of post-earthquake fire in urban buildings

Post-earthquake fire (PEF) is considered one of the most high risk and complicated problems affecting buildings in urban areas and can cause even more damage than the earthquake itself. However, most standards and codes ignore the implications of PEF and so buildings are not normally designed with PEF in mind. What is needed is for PEF factors to be routinely scrutinized and codified as part of the design process. A systematic application is presented as a means of mitigating the risk of PEF in urban buildings. This covers both existing buildings, in terms of retrofit solutions, and those yet to be designed, where a PEF factor is proposed. To ensure the mitigation strategy meets the defined criteria, a minimum time is defined – the safety guaranteed time target – where the safety of the inhabitants in a building is guaranteed.     

North–South Outsourcing,Immigration, and Skilled Wages: Through the Lens of Incomplete Contracts

The forces of immigration and offshore outsourcing are subject to factors that leave sufficient room for incompleteness in a contract. The authors present a model that allows one to compare the effects of immigration and offshore outsourcing, on skilled wage, when both are subject to contractual incompleteness. They capture the sensitivity of the effect on the skilled wage, of immigration and offshore outsourcing to complementarities between firm‐specific human capital and human capital that is transferable across firms manufacturing intermediate goods. In particular, the authors show that the North–South gap in skilled wages is likely to (i) increase through the forces of immigration when the intermediate goods' technology is super‐modular in the North but sub‐modular in the South and (ii) decrease through the forces of outsourcing when the intermediate goods' technology is sub‐modular in the North but super‐modular in the South.     

Higher education and growth performance of Pakistan: evidence from multivariate framework

This study investigates the relationship between higher education and economic growth in Pakistan by using the annual time series data from the period of 1980–2011. The ARDL bound testing cointegration approach confirms the valid positive relationship between higher education development and economic growth in long run as well as in short run. Results of Granger causality test, Toda and Yamamoto Modified Wald causality test and variance decomposition test confirm the bidirectional causal relationship between higher education and economic growth in Pakistan. Results of rolling window estimations suggest that the contribution of higher education in economic growth is significantly increased after the formation of higher education commission of Pakistan in 2002. It is clear from our findings that higher education commission plays an important role in the development of higher education in Pakistan which leads to enhance economic growth. It is recommended that policy makers should make policies to strengthen the higher education commission to ensure continuous and rapid economic growth in Pakistan.     

Foreign capital inflows, economic growth and stock market capitalization in Asian countries: an ARDL bound testing approach

This study investigates the effects of foreign capital inflows and economic growth on stock market capitalization in 18 Asian countries by using the panel data from the period of 2000–2010. The ARDL bound testing cointegration approach confirms the valid long run relationship between the considered variables. Results indicate that foreign direct investment has significant negative and economic growth has significant positive relationship with the stock market capitalization, whereas, the results of workers’ remittances is found insignificant in long run. The error correction model confirms the significant positive relationship of economic growth and workers’ remittances while, FDI has negative and significant impact on stock market capitalization in short run. Results of causality test based on Toda and Yamamoto (J Econom 66: 225–250, 1995) show the bidirectional causal relationship of foreign direct investment and economic growth with stock market capitalization. However, no causal relationship is found in between workers’ remittances and stock market capitalization. It is suggested that investor should not idealize the inflow of workers’ remittances to invest in Asian stock markets in long run. Simultaneously, size of the economy is a better leading indicator for Asian stock markets. On the other hand, inflows of FDI may mislead the investor to invest. Investor should keep on eye whether FDI come in the competition of domestic market or not? If this happens so investor should not invest in the stock market of host country.     

Unemployment Benefits and Entrepreneurship

Several recent empirical papers show that unemployment benefits crowd out nascent entrepreneurs. In the present paper provide theoretical support in favour of this interesting result. Over fairly general preference patterns we obtain a measure of the opportunity cost of entrepreneurs in the presence of unemployment benefits and derive conditions under which potential entrepreneurs suffer as unemployment benefits rise. We formulate a clear transmission mechanism in the labour market that links unemployment benefits to occupational choice for a group of risk‐averse individuals.     

Islamic economics versus market economics： The concept of taxations

Taxation plays a major role in both market economics and Islamic economics. The difference is that in market economics, the tax system has evolved throughout the centuries in order to address the constant change in market-based societies. In Islamic economics, however, the tax system bases on the writings of the Qur＇an and the principles of shariah. As a result, it did not flourish as the needs of Islamic society changed. Therefore, governments in Islamic countries that seek to follow Islamic law are facing major economic challenges. Recently, some Islamic scholars have asserted that Islamic governments can go beyond the explicit instructions of the Qur＇an and impose taxes as needed. They justify their arguments based on the interpretation of Qur＇anic verses. This paper briefly compares both rationality and the methods of taxation in both market economics and Islamic economics, and further elaborates on the shortcomings of the original Islamic tax laws.     

Market interconnection and wages

We show that wage behavior as well as the skilled–unskilled wage gap depend on elasticity of import demand. Although, our analysis is in the spirit of the Stolper–Samuelson theorem, factor intensity plays no role in our results.     

Synthesis of Complex Criteria Decision Making: A Case Towards a Consensus Agreement for a Middle East Conflict Resolution

The title of this paper reflects both the process and the outcome of the current undertaking. Frustrated with the current state of the Middle East but encouraged by earlier attempts at modeling complex problems, the authors participated in a panel discussion assembled to address the conflict and propose a possible road-map to peace. However, the participants of this project did not come to a single course of action that will result in peace in the Middle East but did reach a consensus agreement about a resolution that needs to be managed. This paper explores the process, the outcome and the factors that influence the decision as well as potential pitfalls. The Analytic Network Process (ANP), a well known multicriteria decision making approach, applied frequently in recent years to examine conflicts around the world, is used in this analysis. It provides a framework for synthesizing judgments on the diverse aspects of the problem represented in the structure of the decision. It pieces together these judgments in a holistic and logical way.     

Manufacturing and the Trade Balance

When the world shifted to the regime of flexible exchange rates after 1970, economists expected that large trade imbalances would soon disappear. Instead, such imbalances not only persisted but soared in the 1980s and 1990s, in spite of significant changes in important currencies such as the yen, the mark and the dollar. This paper reports that manufacturing importers tend to suffer trade deficits whereas exporters of manufacturing products tend to enjoy trade surpluses. The reason lies in the higher rates of productivity growth experienced by exporters of manufactures.