Resource utilization and procedure-related costs associated with transfemoral transcatheter aortic valve replacement

Aims: Transcatheter aortic valve implantation (TAVI) is an alternative to surgical valve replacement for patients with aortic stenosis (AS). This study assessed the impact of changing from a self-expandable (SE) valve to a balloon-expandable (BE) valve on healthcare resource use and procedural costs in a population of inoperable AS patients.

Methods: In this retrospective single center study, data for 195 patients who received either an SE or a BE valve between 2010–2014 were collected. Procedural and post-procedural healthcare resource use and cost parameters were determined for the two groups.

Results: The study showed that overall procedural time, including time required by medical personnel, was significantly shorter for TAVI using a BE compared with an SE valve. Post-surgery, patients in the BE valve group had significantly shorter hospital stays than the SE valve group, including significantly fewer days spent in the intensive care unit (ICU). Additionally, trends towards reduced 30-day mortality, incidence of new permanent pacemaker implantation, and incidence of blood transfusion were observed in the BE valve group compared with the SE valve group. Finally, total procedural costs were 24% higher in the SE compared with the BE valve group.

Limitations: The BE valve data were acquired in a single year, whereas the SE valve data were from a 5-year period. However, a year-by-year analysis of patient characteristics and study outcomes for the SE valve group showed few significant differences over this 5-year period.

Conclusions: Overall, changing from an SE to a BE valve for TAVI in patients with severe AS reduced both healthcare resource use and procedure-related costs, while maintaining patient safety. For healthcare providers, this could increase efficiency and capacity within the healthcare system, with the added advantage of reducing costs.     

Determinants of patent value: Insights from a simulation analysis

This paper contributes to understanding the determinants of patent value. By drawing on a real options approach, we develop a theoretical model of patent value, which explicitly considers the uncertainty about future value. On this basis, we rely on Monte Carlo simulations with data from a case study in a large chemical firm to estimate patent value according to our model. In the simulation analyses, we compare an R&D project with patent protection and the same project without patent protection. The difference of the values of the two projects is the surplus in profit that may be expected from having a patent covering the project. This surplus is regarded as the value that is directly attributable to the patent. The results of the simulation analyses indicate that the development costs and expected net cash flows of a patent-protected project are higher than of an unpatented project. The higher net cash flows outgrow the increased development costs, and patent value is positive. However, this value is smaller than the overall project value of the patent-protected R&D project.     

“Fact or artifact? Empirical evidence on the robustness of compromise effects in binding and non-binding choice contexts”

In this article, the compromise effect (CE) is investigated according to which the choice share of a particular product is expected to increase when it is in an intermediate position in a subset of a product line. In a laboratory-based replication study, we tested CE both in hypothetical non-binding settings most commonly used in previous research on CE as well as in settings where experienced consumers make unforced and binding purchase decisions between real brands of two particular categories. While results prove robustness of the compromise effect even in the binding choice context, its magnitude is significantly reduced, hence indicating a hypothetical bias. Thus, since the CE is evidently less prevalent in the more realistic binding choice setting, compromise effects must be considered overrated to a certain degree in the previous studies on hypothetical decisions.     

Verkaufen als Unternehmensaufgabe

Jeder Mitarbeiter sollte sich als Verk?ufer fühlen. Denn die Zeiten, in denen das Verkaufen von Produkten und Dienstleistungen ausschlie?lich Aufgabe der Vertriebsabteilung war, sind l?ngst vorbei. Heute gibt es kaum einen Bereich, der keinen Beitrag zum Vertriebserfolg leisten kann. Dieser Artikel zeigt, wie man die Vertriebsorientierung des gesamten Unternehmens erh?hen kann.     

Testing measurement invariance using multigroup CFA: differences between educational groups in human values measurement

This article applies the testing procedures for measurement invariance using multigroup confirmatory factor analysis (MGCFA). It illustrates these procedures by investigating the factorial structure and invariance of the Portraits Value Questionnaire (PVQ, Schwartz et al.: J. Cross Cult. Psychol. 32(5), 519–542 (2001)) across three education groups in a population sample (N  =  1,677). The PVQ measures 10 basic values that Schwartz postulates to comprehensively describe the human values recognized in all societies (achievement, hedonism, self-direction, benevolence, conformity, security, stimulation, power, tradition and universalism). We also estimate and compare the latent means of the three education groups. The analyses show partial invariance for most of the 10 values and parameters. As expected, the latent means show that less educated respondents attribute more importance to security, tradition, and conformity values.     

Winners and losers: a micro-level analysis of international outsourcing and wages

Abstract.  Our paper investigates the link between international outsourcing and wages utilizing a large household panel and combining it with industry-level information on industries' outsourcing activities from input-output tables. This approach avoids problems such as aggregation bias, potential endogeneity bias, and poor skill definitions that commonly hamper industry-level studies. We find that outsourcing has had a marked impact on wages. Applying two alternative skill classifications, we find evidence that a 1 percentage point increase in outsourcing reduced the wage for workers in the lowest skill categories by up to 1.5%, while it increased wages for high-skilled workers by up to 2.6%. This result is robust to a number of different specifications.     

Desiderata und Perspektiven der Forschung über parasoziale Interaktionen und Beziehungen zu Medienfiguren

Parasocial interactions and relationships are a frequently used framework for studies on media reception in communication research. In spite of its long tradition, however, the concept is still in need of several clarifications. Therefore, this article explores ways to increase the explanatory value of the concept. We briefly present major problems of the definition and conceptualization of parasocial interactions and relationships, namely the understanding of the key elements interaction, relationship, and persona, and suggest first ideas for their solution. Subsequently, opportunities are outlined to enhance the concept by integrating other theories and concepts on media reception and interpersonal perception, taking them from communication research and psychology. Finally, we discuss methodological problems in general and specific shortcomings of the quasi-standard measure, the Parasocial-Interaction-Scale.     

Upper echelons and portfolio strategies of venture capital firms

In this study we analyze how the composition of the top management team (TMT) influences the portfolio strategy choice in venture capital (VC) organizations. We develop a model of risk perception to investigate how education and experience of TMT members impact whether VC organizations invest with a focus on early stage ventures or not, specialize or diversify across industries, and invest with a broad or narrow geographic scope.Evaluation of data on TMTs and portfolio strategies of 136 European VC firms revealed that VC firms with higher proportions of TMT members with science/engineering education and entrepreneurial experience more likely invest with an early stage focus. Furthermore, TMTs with more management education diversify their portfolios more across industries. Finally, the more international experience TMT members of VC organizations have, the broader the geographic scope of investees. We discuss the implications of our findings for the VC literature.     

Trade liberalization and industrial restructuring through mergers and acquisitions

This paper analyzes mergers and acquisitions (M&As) as a channel of industrial restructuring after trade liberalization. Using the Canada-United States Free Trade Agreement (CUSFTA) of 1989 as a source of exogenous variation in trade barriers, I show that trade liberalization increased domestic Canadian M&A activity (Canadian firms buying other Canadian firms) by over 70%. There is no robust link between tariff reductions and either domestic U.S. or cross-border M&As. I also provide evidence that domestic M&As transferred resources from less to more productive firms and that the magnitude of the overall transfer was quantitatively important.