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891.
It is argued that the genetic engineering revolution now under way is fundamentally different from other industrial revolutions in that humans are developing the technological power to change themselves. This article begins with an overview of the technology involved, discusses the Human Genome Initiative (HGI) programme and gene therapy research, and then uses several possible future scenarios to discuss potential legal and ethical issues. 相似文献
892.
Assessing and acquiring technology does not have to be chaotic, driven solely by price, clinical preference, and emotion. With the tools available, it can be distilled to a process of organized common sense, which results in maximum flexibility for the user and allows materiel managers to procure the best, most cost-effective equipment for the hospital. 相似文献
893.
Randall S. Billingsley Vittorio Bonomo Stephen P. Ferris 《Journal of Financial Services Research》1992,6(2):137-155
The deregulatory trend and advances in technology during the 1980s removed many restrictions on the ability of U.S. depository financial institutions to obtain and redistribute funds across diverse geographical markets. This pervasive deregulation and innovation should have increased the degree of integration between different geographical financial markets. Yet there is little empirical evidence available on the validity of this expectation. It is important to provide such evidence since much of the U.S. depository institution regulatory policy is predicated on the assumption of highly localized, segmented financial markets. Considering alternative breakpoints at 1980 (DIDMCA) and at 1982 (Garn-St Germain), the current study tests the hypothesis that the degree of geographical financial integration after this period exceeded that prior to this period. Mortgage markets are focused on due to their historical importance in the regulation of funds flows. The study finds a significant increase in the mean contemporaneous correlation among FHLB districts' mortagage rate residuals in a vector-autoregressive system between two test periods. Further analysis shows that the distance between FHLB districts' headquarters and their respective pairwise interdistrict correlation coefficients are negatively related in the prior period but not significantly related in the later period. Economic booms and busts alternated among the districts over the two sample periods in a manner consistent with the reallocation of capital among more integrated financial markets. Individual districts' mortgage rates have been more sensitive to variations in national credit market conditions since deregulation was legally recognized by DIDMCA in 1980. Thus, the collective empirical evidence found in this study indicates that mortgage markets have responded to deregulation and marked technological advances by moving toward a national, highly integrated market. Regulators' preoccupation with highly localized, segmented markets must consequently be reexamined. 相似文献
894.
895.
Sims AC 《Harvard business review》1992,70(3):116-129
Globe Metallurgical Inc., a $115 million supplier of specialty metals, is best known as the first small company to win the Baldrige Award in 1988. But there is much more to this gutsy little company than total quality. During the 1980s, Globe transformed itself from a rust-belt has-been on the verge of bankruptcy into a high-technology, high-quality industry leader. Along the way, the company went private in a management-led leveraged buyout, embraced flexible work teams, adopted a high-value-added, niche marketing strategy, and took its business global. Leading the way in Globe's reinvention was Chief Executive Arden C. Sims, the slow-talking son of a West Virginian coal miner. When he joined the company in 1984, Sims had no experience in the new managerial techniques. He was a product of the old school of management: cut costs and trim operations to regain competitiveness. But he soon discovered that old-style management was not enough to battle offshore competitors, an unproductive work force, rising costs, and outdated production technology. He was forced to go looking for new ideas and practices. In a succession of learning experiences, Sims attended a seminar on total quality in 1985, paving the way for the company's quality program; he discovered the power of flexible work teams when management was forced to run the furnaces during a year-long strike; he organized an LBO, allowing him to change the work order even more dramatically; and he took the company global and into highly profitable niche markets by severing a long-standing relationship with Globe's sales and marketing representative. As a result of these and other changes, Globe leads the specialty metals industry in virtually all performance measures. 相似文献
896.
Dr. Wei-Bin Zhang 《Journal of Economics》1992,55(1):43-63
This study suggests a model of economic development which treats knowledge accumulation as an endogenous variable. It examines possible dynamic processes in an economic system which accumulates knowledge from developed nations. We describe the dynamics of the system by the interactions of three variables—economic conditions, level of knowledge, and openness. The introduction of openness as an important endogenous variable is due to the fact that the development model considered here is primarily concerned with the economic dynamics of the People's Republic of China. We are especially interested in nonlinear phenomena such as catastrophes and limit cycles. We show that small shifts in political policies may result in great social structural changes.The author is very grateful to two anonymous referees for important comments and to an anonymous referee for linguistic help. 相似文献
897.
Donald G. Saari 《Economic Theory》1992,2(3):359-388
Summary Two theorems are given; the first extends the Sonnenschein-Mantel-Debreu theorem characterizing aggregate demand functions from the set ofn2 commodities to all of the 2
n
–(n+1) subsets of two or more commodities. The second theorem concerns spatial voting models for k2 candidates over a space of n2 issues. The theorem characterizes the sincere elecion rankings of thek candidates over all of the 2
n
–1 subsets of one or more issues. Both theorems have the same kind of conclusion; anything can happen. By demonstrating the mathematical reasons for these conclusions and by recalling related, recent results from statistics, voting, and economics, it is argued that this anything can happen conclusion is the type one must anticipate for aggregation procedures; particularly for the processes commonly used in economic models where the procedure is responsive to changes in agents' preferences, changes in data, etc.I am pleased to acknowledge conversations with L. Hurwicz, A. Mas-Colell and C. Simon about this material. In particular, I want to thank J. Jordan for his several helpful suggestions. Also, I benefited from comments made at meetings and seminars where these results were presented; this includes a June, 1990, conference in Stockholm, Sweden. Some stylistic suggestions were made by Arvid and Padon Kalinen. This research was supported, in part, by NSF Grant IRI-8803505. 相似文献
898.
Randolph M. Lee 《Environmental and Resource Economics》1992,2(6):iii-iii
Editorial
An appreciation of our referees 相似文献899.
Operational Research and the environment 总被引:1,自引:1,他引:0
The discipline of Operational Research (OR) is primarily concerned with improving the effectiveness and efficiency of decision processes. These processes take place everywhere in society: industry, banking, agriculture, government, politics. Frequent use of mathematical optimization models is typical of OR. Since the early '80s these models are increasingly packaged in a user-friendly way, as Decision Support Systems. In the following we will illustrate how OR can be used to describe and solve a number of environmental problems. 相似文献
900.
A. D. Rikun 《Environmental and Resource Economics》1992,2(6):593-604
This paper examines a scheme of economic incentives for environmental protection, in which spatially differentiated pollution taxes are in use in compensating the pollution abatement costs. A simple mathematical model is described which determines an incentive system that encourages polluters to reduce the discharges to an acceptable level of ambient quality standards in a cost-effective manner. It is shown that the vector of pollution charges has to be proportional to the marginal abatement cost vector, but is smaller than the latter in magnitude. It is demonstrated that a necessary incentive effect may be achieved even if the total pollution charge is much lower (about three times) than the total abatement costs. It is also estimated how this charge incentive system reconciles conflicting criteria of cost-effectiveness and of equity. These conclusions are verified by numerical experiments with real data. 相似文献