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881.
The economic significance of conditioning information in the presence of costly short‐selling is investigated. Using a compact testing framework, results demonstrate that fixed‐weight stock‐bond portfolios appear inefficient with respect to stock‐bond portfolios with weights determined by extant predictors. However, this result is highly dependent on ex ante knowledge of the predictor set and the ability to short‐sell at low cost. In the absence of such conditions, fixed‐weight stock‐bond portfolios appear efficient with respect to conditioning information.  相似文献   
882.
The increasing interest in international migration and the African dimensions of that migration in Europe has received considerable attention by scholars recently. Accounting has been largely absent from contributing to that research. In this article, I address how the limits of a managerialist social accounting of African migrants in Naples, Italy might offer useful insight into the social and economic dimensions of irregular African migrants working in the city's underground economy. To do this, I employed the methods of anthropology and ethnographic study. In a case study of a social audit introduced by a public transit company to control petty crime, I examine how that audit produced an excess knowledge about African migrants that extended beyond it procedural purpose. Beyond the limits of its structure it revealed significant knowledge about the informal economies of remittances sent to Africa.  相似文献   
883.
884.
We show that in large finite economies, core allocations can be approximately decentralized as Nash (rather than Walras) equilibrium. We argue that this exercise is an essential complement to asymptotic core equivalence results, because it implies that in some approximate sense individual attempts to manipulate the decentralizing prices cannot be beneficial, which fits precisely the interpretation of asymptotic core convergence, namely the emergence of price taking.  相似文献   
885.
Summary This note provides an elementary short proof of the Knaster-Kuratowski-Mazurkiewicz-Shapley (K-K-M-S) Theorem based on Brouwer's fixed point theorem. The usefulness of the K-K-M-S Theorem lies in the fact that it can be applied to prove directly Scarf's (1967) Theorem, i.e. any balanced game has a non-empty core. We also show that the K-K-M-S Theorem and the Gale-Nikaido-Debreu Theorem can be proved by the same arguments.We wish to thank Roko Aliprantis for useful comments.  相似文献   
886.
The design and creation of anything innovative requires knowledge creation, which in turn often depends upon the introduction of innovative information technology (IT). Since design-related practices are deeply integrated with particular IT artifacts, it is no trivial task to migrate practice-based knowledge to unfamiliar IT artifacts. To explore the challenges associated with such migration, we develop the concept of embeddedness of IT artifacts by drawing on research that highlights the critical role of representational artifacts in knowledge, design, and distributed cognition. We then inductively analyze interview data from an in-depth case study of Frank Gehry, a world-renowned and radically innovative architect known for his use of sophisticated 3D computer-aided design (CAD) technology. By studying construction firms' transition from 2D CAD to 3D CAD, we identify four relevant themes associated with embedding new artifacts into knowledge-creating practice: (1) motivating the new artifact; (2) anchoring the new artifact in the old; (3) experimenting with the new artifact; and (4) confidence in using the new artifact. Through the generation of a process theory of embedding, we elaborate on how this perspective complements and extends research on IT adaptation and assimilation, and discuss the relevance of continuing to develop the IT embeddedness perspective given the continuing need for increased levels of IT-enabled innovation.  相似文献   
887.
Jozef Lodewijk Maria Teugels was born in Londerzeel, Belgium, on February 20, 1939. He received his high school education at Sint-Lievenscollege in Antwerp. He obtained a Candidate diploma in Physics in 1961 and a License degree in Mathematics in 1963 at the Catholic University of Louvain. After serving one year in the army, he obtained his MSc in 1966 and his PhD in 1967 at Purdue University, with Marcel F. Neuts as advisor. In 1967 he was appointed at the Catholic University of Louvain and promoted to Full Professor in 1973. He remained in Leuven until his retirement in 2004. He chaired the Department of Mathematics over the periods 1970–77 and 1982–89. He has held visiting positions at numerous universities in the United Kingdom, Portugal, the United States of America, South Africa, Japan, Indonesia and Australia.  相似文献   
888.
Austrian ideas about the firm have grown rather naturally out of the central body of Austrian thought with its focus on entrepreneurship, subjectivism and market processes. In this paper we critically evaluate some Austrian ideas on the firm, with particular attention to the concept of entrepreneurial judgment. We then describe recent empirical work in entrepreneurship that has identified key elements of what might reside inside the “black box” of entrepreneurial decision making. We conclude that expertise in this type of decision making embodies procedural knowledge that is adaptive in the absence of substantive knowledge, i.e. without judgment.  相似文献   
889.
Little is known about the causal impacts of public transit on local air pollution. Exploiting variation in transit availability resulting from transit strikes in 18 Canadian cities between 1974 and 2011, this study identifies the short-run effect of public transit on air pollution. Our findings indicate that transit leads to a 3.5 part per billion increase in nitrogen oxides while having no statistically significant effect on carbon monoxide or PM2.5. Estimates are robust to a series of specification tests and magnitudes are consistent with a calibrated simulation model. Overall, the results suggest that expanding the current configuration of public transit in North American cities is unlikely to yield improvements in local air quality.  相似文献   
890.
Abstract

Aims: The study evaluated the real-world cost of treatment in multiple sclerosis (MS) patients initiating infused disease-modifying-therapies (DMT) in the United States.

Materials and Methods: This retrospective cohort study using administrative claims data included adult patients with MS initiating index infusion DMT (ocrelizumab (OCR), natalizumab (NTZ) or alemtuzumab (ATZ)) from April 2017–September 2018 with 6-months pre/12-months post-index continuous enrollment. The primary cohort included patients who had prescribed annual dosing visits indicated by the approved product label (PL): 3 OCR, 5 ATZ, and 12–13 NTZ infusion visits within the first year of initiation. Annual treatment cost was the sum of all costs on index DMT infusion visit dates. Costs were summarized for a primary and secondary cohort of patients receiving additional doses than prescribed in PL (>3 OCR, >5 ATZ, and >13 NTZ infusion visits); and an overall cohort of patients who met minimum required annual dose (≥3 OCR, ≥5 ATZ, and ≥12 NTZ), further stratified by insurance type.

Results: For patients in the primary cohort (123 OCR, 18 ATZ, and 48 NTZ), mean (standard-deviation) annual cost of treatment with OCR, ATZ, and NTZ cohorts was $72,066 ($34,480), $121,053 ($51,097) and $93,777 ($38,815), respectively. Among patients initiating OCR and NTZ, 15 and 6% respectively, had additional infusion visits leading to greater costs. Mean annual costs of index infusion DMT treatment in the overall cohort (162 patients treated with OCR, 18 with ATZ, 56 with NTZ) were $80,582, $121,053, and $93,807, respectively. The mean costs for commercial enrollees were higher than those for MAPD enrollees.

Limitations: Small sample size, limited population generalizability, and cost-reduction for ATZ beyond the second year need to be accounted for.

Conclusions: Real-world infusion DMT treatment costs for commercially insured patients were higher than perceived expenditures based on wholesale acquisition cost and administration costs via a physician-fee schedule. Consideration of real-world costs in cost-effectiveness and treatment/coverage decisions is needed.  相似文献   
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