创新主体对研发全要素生产率的影响实证研究

利用非参数的Malmquist生产率指数方法研究了1999-2008年我国研发全要素生产率(TFP)的变动及其分解,在对TFP变动的时序特征及地区差异进行比较分析的基础上,考察了公共和企业创新对研发TFP的影响。研究表明:我国研发TFP的增长主要是由技术效率推动的,技术进步改善的作用相对有限,研发技术进步与技术效率显著负相关,地区之间研发TFP增长率也存在显著差异;公共和企业研发对研发TFP的影响均为负,且企业研发对TFP增长的负面效应大于公共研发。     

加拿大总督戴维·约翰斯顿访渝 在重庆大学探讨双方教育科技领域合作机会

正我的5个女儿有4个都来过中国学习或参加交流项目,其中有两个汉语都讲得很不错。出国学习给她们带来很大的提升,希望你们以后能得到同样的体会和经历。2017年7月11日,加拿大总督戴维·约翰斯顿一行访问重庆,在美丽的南滨路,与计划前往加拿大学习的部分中国学生共进火锅晚餐,并寄语中国青年:希望你们通过在加拿大的学习生活,变得更有好奇心、包容心、判断力和同理心,这些可贵的特质将伴随你们成长。     

父母陪伴对青少年非认知能力的影响——基于亲子共餐视角的准实验研究

采用中国教育追踪调查(CEPS)两期面板数据,利用双重差分倾向得分匹配法(PSM-DID),从亲子共餐这一微观视角来探究父母陪伴对青少年非认知能力的影响。结果显示,亲子共餐频率的降低对青少年的非认知能力总水平及其分维度情绪稳定性、宜人性和尽责性均有显著的负向影响,反之,亲子共餐频率的提高对青少年的非认知能力总水平有显著的正向影响,但具体从各维度来看,亲子共餐频率的提高仅对青少年的宜人性产生显著的正向影响,而对情绪稳定性和尽责性均无显著影响。     

锚企业与科技新城共生模式研究:以阿里巴巴和杭州未来科技城为例

以阿里巴巴和杭州未来科技城为例,采用Logistic模型探讨锚企业与科技新城共生模式,结果表明：总体而言,阿里巴巴和未来科技城属于互利共生模式,阿里巴巴成长会促进未来科技城发展,而未来科技城发展也会反哺阿里巴巴的成长。2013-2016年两者共生系数之间的差值不断缩小,表明阿里巴巴和杭州未来科技城的共生模式从偏利共生转向互利共生。     

Cost-effectiveness analysis of utidelone plus capecitabine for metastatic breast cancer in China

Abstract

Objective: To estimate the cost-effectiveness of utidelone plus capecitabine therapy compared to capecitabine alone in patients with metastatic breast cancer (MBC) resistant to anthracyclines and taxanes treatment in the Chinese context and provide a reference for the marketing of utidelone in China.

Methods: A Markov model was developed based on the NCT02253459 clinical trial to simulate the clinical course of patients with metastatic breast cancer who had received taxanes and anthracycline therapy. The quality-adjusted life years (QALYs) and Incremental Cost Effectiveness Ratio (ICER) were then analyzed to evaluate the benefits. Two-parametric Weibull distribution was conducted to fit PFS and OS curves by using R. Sensitivity analyses were performed to evaluate the stability of the model designed.

Results: The addition of utidelone increased the cost and QALYs by $13,370.25 and 0.1961, respectively, resulting in an increased ICER of $68,180.78 per QALY. The most sensitive influential parameter on ICER was the price of utidelone. At the threshold of willingness-to-pay (WTP) of $24,380 (3 per capita GDP of China), the cost of utidelone per 30?mg of less than $18.5, $33.7, and greater than $48.8 resulted in a 100%, 50%, and 0% possibility of cost-effectiveness, respectively. The addition of utidelone was not cost-effective when it was $115.4 per 30?mg—the price of its analog paclitaxel. In consideration of varied economics levels across China, cost-effectiveness could be achieved with the price of utidelone ranging from $5.2 to $35.9.

Limitations: The survival curves extended beyond the follow-up time horizon, of which data were generated not from the real analyses but from our established two-parameter Weibull survival model.

Conclusion: It is recommended that the price of utidelone would be less than $18.5 per 30?mg in order to obtain cost-effectiveness for metastatic breast cancer patients resistant to anthracyclines and taxanes treatment in China.     

科技金融、企业创新投入与产出耦合协调度及不协调来源

运用耦合协调模型对中国省域科技金融、企业创新投入与产出的耦合协调度进行测度,结果显示,除北京外的中国内地省域耦合协调度整体偏低。进一步运用DEA模型进行测度发现：初始创新投入系统中各要素无效率省域分布比较复杂,企业创新禀赋无效率均值最高;创新中间产出与投入系统中,发明专利与商标权产出有效率,但以此作为中间投入的无效率均值高、省域分布广;最终产出系统中,某些省域新产品销售收入产出不足和技术市场成交额产出不足情况比较突出。据此提出创新初始投入系统协调发展观、创新中间投入与产出质量观和创新最终产出知识产权盈利模式观,以改善创新投入与产出不协调的状况,助力企业转型升级。     

ECONOMIC SANCTIONS REVISITED: ADDITIONAL INSIGHTS INTO WHY THEY FAIL

Economic sanctions have a poor track record in achieving their objectives. In most cases, they are ineffective in bringing about policy change, cause increased suffering in the sanctioned country and reduce opportunities for business. This paper provides additional insights into why sanctions fail by examining two overlooked factors: power–dependency theory and pressure for political stability.     

工科专业外语实践教学构想

工科专业外语教学存在诸多不足,其中实践教学几乎没有。建立不同文本为基础、实施全程参与为核心、进行读写训练为辅助等措施的教学实践方面的探索,必将有力推进专业外语教学改革,提升教师专业外语实践教学能力,提高学生的个人综合文化素质。