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81.
This article examines the effects on the demand of voluntary labeling for the use of genetically modified growth hormone for retail fluid milk using supermarket scanner data. Retail fluid milk tracks one of the first biotechnology products approved, is fairly standardized and ubiquitous, and allows for cross-sectional differentiation between labeled and unlabeled products and between conventional and organic brands. The results indicate that voluntary labeling increases the demand for recombinant bovine growth hormone free milk. In addition, the estimated effects of labeling appear to have increased over time.  相似文献   
82.
Pharmaceutical firms are reluctant to disclose proprietary information about a drug's likelihood of approval by the U.S. Food and Drug Administration (FDA) for fear of losing their competitive advantage. Instead, firms may use signals, like the FDA fast‐track designation, to indicate to investors the likelihood of a drug's approval. This analysis uses an event study methodology, with stock and market data from the Center for Research in Security Prices. The results show that the fast‐track designation is a strong, positive signal to investors (1998–2015), but its strength has markedly decreased over time. Results also show that the signal is strongest for the smallest firms. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
83.
In the context of high-risk industries, risk assessment takes place not only through standardized methods for risk analysis, but is frequently negotiated and discussed as an integral part of operational decision-making. This is not least the case in the context of operational planning. Frequent changes in operations require ongoing assessment of risk as tasks are rescheduled and resources reallocated. The current study explores how professionals account for the presence or absence of risk in a setting in which risk analysis is not the primary objective. With data from the offshore petroleum industry, the rhetorical aspects of risk assessments are examined. A series of interprofessional planning meetings were video recorded, transcribed, and analyzed using a rhetorical discourse analytic framework. The data are analyzed at a micro-interactional level in order to study how accounts of risk are presented and negotiated in this particular setting. The meaning and consequences of operational plan changes, and their implications for safety, are seen as negotiated discursively through interprofessional meeting talk. The analysis shows that accounts of risk are characterized by shifting rhetorical strategies that can be heard to echo established risk discourses often referred to as ‘technico-scientific’ and ‘contextualized’ conceptions of risk. Rhetorical devices are used interchangeably and strategically by the participants as they account for risk from their respective institutional positions and their specific areas of expertise and responsibility. The accounts are found to be increasingly persuasive and rhetorical in style as disagreements over risk and prioritizations surface. Accounts of risk, then, are not simply objective presentations of probability and consequence, but rather powerful tools for achieving specific professional outcomes. The study contributes to the understanding of risk assessment at its most concrete and practical level; as it takes place through professional interaction in an operational setting.  相似文献   
84.
  • Nonprofit organizations are pertinent players in making the world a better place. Their websites aid in fulfilling their socially beneficial missions by being a platform to present themselves, to interact with stakeholders around the world, and to perform e‐transactions to raise funds. This interdisciplinary research explores nonprofit websites in Thailand, an emerging market, to determine their progress through an adapted e‐business stage model. A manual website decoding process was used to determine the development of websites, within the sector. On average, almost three‐quarters of the websites offered interactivity and just less than half conducted online transactions, but internationally connected organizations in Thailand were significantly more likely to do so. The findings suggest that while nonprofit websites in Thailand are progressing, there is significant lag between local Thai websites and those that have international connections. While the model successfully provided new data for understanding nonprofit websites in less developed markets, it may need to be modified in future studies.
Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
85.
86.
This paper applies standard input-output methodology to estimate the employment affects of aid flows for the UK and the FRG. The conclusion is at variance with what some other economists have claimed earlier in that it shows that aid flows to developing countries do not generate a lot of jobs at home. Indeed, it is estimated that they generate fewer jobs than alternative uses of money at home, hence this paper contends that the argument of ‘self-interest’ for channelling aid to developing countries does not hold water. It is concluded that overseas development aid as a tool of alleviating domestic problems (unemployment, regional problems etc.) is pretty ineffective and aid allocation priorities should be based on grounds other than those of domestic economic considerations.  相似文献   
87.
Objectives: To examine suboptimal responses (SR) in attention deficit hyperactivity disorder (ADHD) among pediatric patients in the Texas Medicaid program receiving osmotic-release oral system methylphenidate (OROS-MPH) or lisdexamfetamine (LDX) and apply an SR prediction model to identify patients most likely to experience an SR to either OROS-MPH or LDX therapies.

Methods: A retrospective cohort study was conducted using Texas Medicaid claims data of ADHD children and adolescents (6–17?years of age) initiating OROS-MPH or LDX. Primary SR endpoints were drug discontinuation, switching, and augmentation 12-months post-ADHD drug initiation. Logistic regression models were developed to predict SR to OROS-MPH and LDX in 1:1 matched groups of children and adolescent cohorts.

Results: A total of 3,633 children and 1,611 adolescents were matched for each cohort. SR was observed among more children (76.4% vs 72.3%; p?p?=?0.002) initiating OROS-MPH compared to LDX. Patient sub-groups with the highest predicted risk of OROS-MPH SR experienced significantly lower observed SR rates (p?Conclusions: This study demonstrated how a personalized medicine approach using administrative claims data can be used to identify sub-groups of child and adolescent ADHD patients with different risks for suboptimal response with OROS-MPH or LDX in a Medicaid population.  相似文献   
88.
China's accession to the WTO in 2001 completed the country's entry into the global economy. We investigate environmental implications of WTO-accession. There are several hypotheses in this area: The scale hypothesis says that production is scaled up and in turn, pollution increases. The technique hypothesis says that production methods become cleaner and pollution decreases. The composition hypothesis says that composition of industries changes and pollution reflects the new composition. We analyse the relative strength of the hypotheses by means of an environmental CGE-model, and in the case of air pollution find support for a composition effect in favour of clean industries. Thanks to the composition effect, emissions to air of greenhouse gases fall. Emissions of particles and SO2 also fall, but emissions of NOx and VOC rise. Since particle and SO2-emissions fall we estimate that public health improves.  相似文献   
89.
Based on the theory of professional competition, this paper identifies and investigates four strategic options of supreme audit institutions (SAIs) through a case study of four Nordic national audit offices: a performance auditing strategy; a financial auditing strategy; a portfolio strategy; and a hybrid strategy. The analysis of the Nordic SAIs shows that while one SAI appears to have adopted a hybrid strategy, the portfolio strategy has been chosen by the three other SAIs, although with some variations in the portfolio. The paper concludes by discussing the implications of these strategic options for public sector auditing.  相似文献   
90.
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