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81.
This paper reports an experiment designed to assess the effects of a rotation in the marginal cost curve on convergence in a repeated Cournot triopoly. Increasing the cost curve's slope both reduces the serially-undominated set to the Nash prediction, and increases the peakedness of earnings. We observe higher rates of Nash equilibrium play in the design with the steeper marginal cost schedule, but only when participants are also rematched after each decision. Examination of response patterns suggests that the treatment with a steeper marginal cost curve and with a re-matching of participants across periods induces the selection of Nash Consistent responses. 相似文献
82.
Der-Yuan Chen Chao-Hsiun Tang Lindsay Claxton Satish Valluri Robert A. Gerber 《Journal of medical economics》2019,22(8):777-787
Aims: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This analysis investigated the cost-effectiveness of the second-line treatment with tofacitinib, compared with adalimumab, both plus methotrexate (MTX), in patients with moderate-to-severe RA and an inadequate response to the first-line MTX, from a Taiwan National Health Insurance Administration perspective.Materials and methods: A patient-level simulation model was used to project lifetime costs and quality-adjusted life-years (QALYs). Base-case analysis compared second-line treatment with tofacitinib 5?mg twice daily plus MTX vs adalimumab 40?mg every 2?weeks plus MTX. Patients switched or discontinued treatment due to a lack or loss of effectiveness or a serious adverse event. Efficacy was measured by change in Health Assessment Questionnaire-Disability Index (HAQ-DI) score. HAQ-DI scores were used to predict mortality and resource utilization, and were mapped onto utility values to estimate QALYs. Efficacy and safety data were derived from clinical trials and other secondary sources. Uncertainty in model parameters was explored using one-way deterministic and probabilistic sensitivity analyses.Results: Patients gained 0.09 more QALYs with second-line tofacitinib plus MTX compared with adalimumab plus MTX (5.13 vs 5.04, respectively) at an additional cost of New Taiwan Dollars (NT$) 12,881. The incremental cost-effectiveness ratio was NT$143,122/QALY. One-way sensitivity analysis confirmed the base-case result was robust.Limitations: The lack of available clinical data, particularly for HAQ-DI scores, may introduce some bias in the analysis. No patients were in an early stage of RA, which may limit the generalizability of these results. Base-case results from our study are not necessarily generalizable to countries with healthcare systems that differ considerably from Taiwan.Conclusions: From a payer perspective, second-line treatment with tofacitinib plus MTX is a cost-effective treatment strategy, compared with adalimumab plus MTX, in patients with moderate-to-severe RA in Taiwan.Trial registration: ClinicalTrials.gov identifier: NCT00853385. 相似文献
83.
We assess the contribution of European authors to 10 topjournals of economics from 1980 to 1998. Despite efforts on the European Union and national levels topromote academic excellence, European authors still play a minor role in top journals. Examining the development overtime we find little evidence for an increasing share of European contributions. Particular attention has been paidto the educational background of European authors. There is still a segmentation of academic education alonglanguage barriers in continental Europe. However, a considerable proportion of European authors has received a PhD from the US. 相似文献
84.
There is growing evidence of a litigation mentality rampant in organizations, which has created a legalistic mindset in many managers. Increasingly, managerial decisions are becoming dominated by a concern for what is legally defensible at the expense of broader social considerations such as justice and fairness. The papers in this special issue explore how this legalistic mindset has created new organizational and social dilemmas, and situations of law whithout justice. 相似文献
85.
This paper presents empirical evidence that bond mutual funds which have adopted the use of 12b-1 fees have not achieved the goal of lowering expense ratios. Using a model specific to bond funds, as opposed to generic models used in previous studies on equity funds, the analysis confirms that the 12b-1 fee is an additional cost borne by shareholders of the fund without any additional benefit. However, this cost as a percent of the net asset value of the fund has decreased from 1991 through 1994. This reduction coincides with the submission of a proposed rule change by the National Association of Security Dealers concerning maximum sales charges imposed by mutual funds on December 28, 1990 and the implementation of limits on 12b-1 fees which became effective in July of 1993. 相似文献
86.
Whistle-blowing in America business and industry has increased as interest in ethical business behavior and the cost of unethical
behavior have grown. Whistle-blowing plays the important role of helping to fill the gaps in the regulatory system that is
designed to check the abuse of organizational power. However, the practice of whistle-blowing is controversial and whistle-blowers
often pay a high price for their actions. Firms can engage in a number of actions to encourage whistle-blowing. Creating a
climate that encourages employees to report organizational wrong doing and that protects the whistle-blower is critical. To
create such a climate the organization must build trust and cooperation by educating employees in the benefits of ethical
and legal behavior. 相似文献
87.
The relative importance of journals used in operations management research A citation analysis 总被引:1,自引:0,他引:1
Robert J. Vokurka 《Journal of Operations Management》1996,14(4):345-355
Journal rankings are important for a variety of reasons, most importantly as the basis of academic tenure and promotion decisions. A common approach in other fields is the citations methodology which is used in this study to determine the relative importance of various operations management (OM) journals. The citations analysis noted the frequency that all other journals are cited in Decision Sciences, Journal of Operations Management, and Management Science during the period 1992 to 1994. Rankings are provided based on total citations, citations per article, and citations per words published. The study shows that the journals with the most importance to OM research are Management Science, Decisions Sciences and Operations Research. Other journals important to OM research are the Harvard Business Review, Journal of Operations Management, and IIE Transactions. 相似文献
88.
Abstract . The economic performance and the political history of Botswana during 1974-84 contrasted significantly with the experience of virtually every other African country. The South African republic, immediately north of the Republic of South Africa, achieved steady real economic growth with improved social services and provision for its people's basic needs. This was achieved in spite of world recession and drought because its mineral wealth Was reserved for the people and mining companies had to pay for the privilege of extracting that wealth through a tax program limited to appropriating its surplus, while assuring the investors and entrepreneurs an adequate long-term return on capital and enterprise. But sound macroeconomic policies failed to provide even reasonably equitable benefits for the majority of the people. Sound micropolicies are needed to widen access to employment and earned income and to asset accumulation. 相似文献
89.
PROPRIETORIAL CONTROL IN FAMILY FIRMS: SOME FUNCTIONS OF 'QUASI-ORGANIC' MANAGEMENT SYSTEMS 总被引:1,自引:0,他引:1
The purpose of this paper is to investigate the strategies of managerial control which are used by the proprietors of family-owned business enterprises. Interviews with the proprietors and senior managers of businesses in the building industry illustrate the ‘quasi-organic’ nature of management structures. These grant some autonomy to senior managers without threatening proprietorial decision-making prerogatives. Although the family firm has certain distinctive features, similar control strategies designed to ensure that delegated decisions are ‘reliable’ and ‘responsible’ are evident in various types of business enterprise. There is, then, scope for further comparative research within a conceptual framework which does not entirely divorce the family firm from other business organizations. 相似文献
90.
Bias is a much-debated issue in survey research. Answer effects (respondents claim to have behaved differently than they did in reality), nonresponse bias (nonrespondents differ on important variables from the respondents) and stimulus effects (by participating in a previous wave of a study, respondents change their behavior or attitude) can seriously distort the results of survey research. By using data from the 1998 Dutch National Election Study the authors show that the results of election research can indeed be affected by bias. Not only are significant effects found in the distribution of political attitude and voting behavior variables as a result of both nonresponse bias and stimulus effects, it is also shown that relations between variables change as a result of bias. 相似文献