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21.
Bayesian MCMC Mapping of Quantitative Trait Loci in a Half-sib Design: a Graphical Model Perspective
N.A. Sheehan B. Gulbrandtsen M.S. Lund D.A. Sorensen 《Revue internationale de statistique》2002,70(2):241-267
Graphical models provide a powerful and flexible approach to the analysis of complex problems in genetics. While task-specific software may be extremely efficient for any particular analysis, it is often difficult to adapt to new computational challenges. By viewing these genetic applications in a more general framework, many problems can be handled by essentially the same software. This is advantageous in an area where fast methodological development is essential. Once a method has been fully developed and tested, problem-specific software may then be required. The aim of this paper is to illustrate the potential use of a graphical model approach to genetic analyses by taking a very simple and well-understood problem by way of example. 相似文献
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Background risk can influence the performance of insurance markets that must deal with adverse selection when applicants are risk vulnerable, since they are more averse to bearing the insurable risk as a result of their exposures to background risk. We show that background risk always results in a lower deductible for the incentive constrained contract, and that a broader range of markets attains the stable sequential equilibrium cross-subsidized pair of separating contracts. We conclude that background risk always improves the performance of markets for coverage against (insurable) foreground risks that must deal with adverse selection. We also find, however, that these improvements are never sufficient to offset the cost to insureds of bearing the background risk. 相似文献
24.
Small accounting practices (SAP), most of which are sole principals, are an important part of the accounting profession and the Australian economy. This exploratory study identifies issues and challenges experienced by small accounting principals in Far North Queensland, Australia. The findings generally correspond with previous research, ranking staffing and keeping up to date through professional development as key areas of concern, and also highlighting the expectation gap between SAP principals and their clients. Stress emerged as a major concern for principals, and new areas of possible conflict of interests were uncovered. A number of potential areas for future research, including comparative studies in city and suburban areas, have been identified. 相似文献
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Atlantic Economic Journal - 相似文献
26.
"A projection model based on a multivariate continuous state, stochastic process is presented. The model allows multiple time-varying covariates to be used so parameters can be estimated from time series information on health changes and mortality, and their interaction. Health changes are simulated by altering parameters controlling the age trajectory and diffusion of risk factor means, variances, and covariances....By increasing the information used in projections it may be possible to better (a) anticipate the state of health at extreme ages, (b) forecast changes in health at specific ages over time, (c) stimulate the effects of specific interventions, and (d) determine the sensitivity of outcomes to a range of interventions." 相似文献
27.
Tannen MB 《Review of urban and regional development studies : RURDS : journal of the Applied Regional Conference》1992,4(1):32-49
"In this paper 1980 [Brazilian] Census microdata are used to evaluate the experiences of males who moved from the Northeast to the Southeast in the post- 'miracle' period. Using regression analysis, migrant earnings are compared to those of persons who remain in the Northeast, to estimate the average earnings gain from relocating. These results are then disaggregated by education, age at migration, period of residence, and particular sending and receiving location, to provide more specific information on which groups benefit most. Wide variation in gains is observed, but substantial improvements in earnings are reported in most cases." 相似文献
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Ginsberg RB 《Regional Science and Urban Economics》1979,9(4):369-392
The main results of eleven studies of the nature and determinants of the timing of moves and duration of residence effects are presented. The studies (see table 1) illustrate the use of the methodological framework for studying individual histories of the previous article. There are substantial duration of residence effects in most population subgroups, implying that the migration process in non-Markovian at the mocro level and that the semi-Markov model is required. However, characterization of effects and their determinants are shown to depend so heavily on the type of interval and observation scheme used, that only within a comprehensive framework is proper interpretation of empirical results possible. 相似文献
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