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101.
Laurence Hunter argues that although there has been some reference to economic questions in the debate on industrial democracy, they have not received the attention that they deserve. Rather than to provide answers, the purpose of his article is to highlight the importance of the questions, in the hope that others might be encouraged to accept the presented challenge. 相似文献
102.
Michaël Grynberg Claire Murphy Carole Doré Laurence Fresneau Ségolène Paillet Nicoleta Petrica 《Journal of medical economics》2019,22(1):108-115
Objective: To assess the cost-effectiveness (CE) of the originator follitropin-α (Gonal-F) in patients undergoing a medically assisted reproduction (MAR) program in comparison to its biosimilars Bemfola and Ovaleap in a French context.Methods: A CE model was developed for France with a National Health Service (NHS) perspective. Clinical, safety, and dosage data were derived from pivotal clinical trials that compared Gonal-F to Ovaleap and Bemfola. Costs pertaining to drugs, hospitalizations, specialist visits, and examinations were retrieved from the French Programme de Médicalisation des Systèmes d'Information (PMSI) hospital database, literature review, and French clinical experts using 2017?Euro tariffs. In order to test the robustness of results, deterministic one-way sensitivity analyses were carried out on the main variables to assess the impact of treatment cost, probability of birth, ovarian hyperstimulation syndrome (OHSS) rates, and dosage.Results: The average incremental cost per live birth with OHSS and without OHSS was €259.56 and €278.39, respectively, for Gonal-F compared to the pooled biosimilars (i.e. Ovaleap and Bemfola). GONAL-F had an incremental efficacy of 0.06 over the pooled biosimilars. The incremental cost-effectiveness ratio for Gonal-F with OHSS ranged from €3,274.80 to €4,877.76 compared to the pooled biosimilars, owing to the additional live births reported with Gonal-F. Sensitivity analyses also supported results from the base case analyses, with Gonal-F being cost-effective or the dominant strategy in most cases.Conclusion: Gonal-F seems to be a cost-effective strategy compared to its biosimilars Ovaleap and Bemfola, irrespective of the incidence of OHSS events, but further data are needed to confirm these results. 相似文献
103.
Laurence E. Lynn Jr 《Public Management Review》2013,15(2):301-310
Although recent public management reforms in Canada. Mexico and the USA are characterized by similar themes and vocabularies - privatization, customer service, devolution - the nature and extent of actual change reflects the national politics and administrative histories of the three countries. In brief, Canadian public management has been heavily influenced by the need for fiscal retrenchment at both, national and provincial levels, Mexican public management has been influenced by the transition from oligarchic to democratic governance at federal, state and local levels, and USA public management has been preocuppied at the federal level with implementation of the Government Performance and Results Act and with the miscellaneous initiatives organized under the ‘Reinventing Government’ theme as it has been popularized by the Clinton administration. 相似文献
104.
In this paper we investigate the possible values of basket options. Instead of postulating a model and pricing the basket option using that model, we consider the set of all models which are consistent with the observed prices of vanilla options, and, within this class, find the model for which the price of the basket option is largest. This price is an upper bound on the prices of the basket option which are consistent with no-arbitrage. In the absence of additional assumptions it is the lowest upper bound on the price of the basket option. Associated with the bound is a simple super-replicating strategy involving trading in the individual calls. 相似文献
105.
Laurence Van Lent 《European Accounting Review》2013,22(1):197-205
Abstract Chenhall and Moers (European Accounting Review, this issue, pp. 173–195) provide an excellent overview of the econometrics of endogeneity. In response to their discussion I argue that researchers should be courageous enough to set aside endogeneity concerns when their research question is important. Theory does not admit a definite answer to the question whether endogeneity is present in a particular model and econometrics has few technical solutions to offer. Since we cannot be sure endogeneity exists, and if we were to be sure of its existence, there is little we can do about it, researchers are well advised to move on to more serious problems. 相似文献
106.
Jocelyn Husser Laurence Gautier Jean-Marc André Véronique Lespinet-Najib 《Journal of Business Ethics》2014,123(2):327-338
The aim of this study is to examine the decision-making processes at work among French buyers—whether beginners or more experienced individuals, when confronted with a dilemma involving an ethical or non-ethical choice to be made. We go on to illustrate these dilemmas through the use of five original scenarios that reproduce typical situations that arise in a purchasing context in relation to the environment, physical integrity, conflict of interest, or paternalism. Based on 172 participants, the results of our study show that, ethical decision-making depends very clearly on two main factors: expertise and gender. The study also reveals that there is not always a coherent link between ethical choices made and the reasons and justifications given for those choices. Ethical options chosen are not exclusively justified on the grounds of purely ethical reasons but also on the grounds of commercial or economic reasons, or else reasons of avoidance. 相似文献
107.
In 1990 a process of financial liberalization was begun in Peru with the aim of achieving economic stability and sustained development. Due to the economic policies that had been applied throughout the second half of the 1980s, this took place in a context of hyperinflation and financial repression. This article examines the effects that financial liberalization has had on the demand for real balances in Peru and discusses the implications for the conduct of monetary policy. 相似文献
108.
Laurence G. Britton 《Process Safety Progress》1988,7(1):40-50
While a primary strategy for avoiding ignition during silos filling lies in control of the ignition energy of the suspension, it may also be possible to control the energy of on-bed brush discharges created during filling. Two instrument systems are described for investigations in operational, full-scale process equipment. A discussion is made of the effective energies of brush discharges, the effects of process variables on static, and types of charge neutralizer that have been used or proposed. The instrument systems allow pragmatic, in-plant evaluation of the effects of process variables and the benefits of any charge neutralizer system that is used. 相似文献
109.
110.