The sociology of innovation and new biotechnologies

Understanding the social processes that support innovations in new biotechnologies presents an interesting challenge. Evidence from the Australian bioindustry reveals how the development and integration of new biotechnologies is a dynamic social process. Our findings highlight how new technology acceptance and integration rested on the micro‐politics of sense‐making and relational networking.     

Dependence of the Russian defense industry on oil prices: Conversion

The article analyzes the impact of the collapse of world oil prices on the reduction of defense budget, production of weapons, innovative and personnel potential of the defense industry, and on country’s defense capability. Some proposals for the concept of structural changes in the defense industry have been formulated based on experience converting the defense industries in the Soviet Union, the United States, China, and France.     

Nanotechnology and the new technological revolution: Expectations and reality

This paper reviews the existing mechanisms of innovative development in the world economy focusing on emerging technologies markets evolution on the example of nanotechnology. The question has been raised of whether nanotechnologies can provide the core of the new technological revolution, and whether these prospects exist for NBIC convergence. In this connection the development of the global market for nano-enabled products following the 2007–2009 crisis and the reliability of the related development forecasts have been assessed. Particular attention has been paid to peculiarities of nanoenabled product market structure and the impact of stagnating R&D costs in the field of nanotechnology.     

When it pays to have a friend on the inside: contingent effects of buyer advocacy on B2B suppliers

As organizational buying systems grow more complex and sophisticated, suppliers increasingly rely on buyer advocacy: an individual buyer’s efforts to influence his/her colleagues such that the supplier’s standing is improved. Drawing from cognitive response theory, the authors hypothesize an inverted U-shaped relationship between a buyer’s advocacy for a supplier and the customer’s purchases from that supplier. They theorize that this effect is moderated by the advocate’s industry experience and customer–supplier relationship characteristics. An analysis of multisource data from a B2B service provider (Study 1) supports the predicted inverted U-shaped relationship, while a unique dataset from a large industrial supplier (Study 2) provides broad support for the hypothesized moderators. Finally, a randomized experiment (Study 3) replicates key findings and corroborates the theorized cognitive response mechanisms. Findings contribute to the limited literature on buyer advocacy within the organizational buying domain and offer practical implications for suppliers and buyers.

     

Rivaroxaban for non-valvular atrial fibrillation and venous thromboembolism in the Netherlands: a real-world data based cost-effectiveness analysis

Background: Non-vitamin K antagonist oral anticoagulants (NOACs) have been included in international guidelines as important alternatives to vitamin K antagonists (VKAs) for the treatment of venous thromboembolism (VTE) and stroke prevention in non-valvular atrial fibrillation (NVAF). Meanwhile, in the Netherlands, NOACs are widely used next to VKAs. The objective of this study is to estimate the cost-effectiveness of treatment with rivaroxaban compared to VKAs in NVAF and VTE patients in the Netherlands, using data from international prospective observational phase IV studies.

Methods: Two models were developed to represent NVAF and VTE patients, populated with patients from the XANTUS (NCT01606995) and XALIA (NCT01619007) international prospective observational studies. The 1-year cost-effectiveness of rivaroxaban use, compared to VKAs, was explored in a population consisting of NVAF and VTE patients (base case) as well as for four scenarios with sub-populations: NVAF patients only, VTE patients only, NVAF patients with unstable international normalized ratio (INR), and NVAF patients using an INR self-measuring device.

Results: In the base case, rivaroxaban saved €72,350 and gained 21 quality-adjusted life-years (QALYs) in a simulation of 2,000 patients over the use of VKAs. Ergo, rivaroxaban was dominant over VKAs. The probabilistic sensitivity analysis showed a probability of 85% for rivaroxaban being dominant and 100% at a willingness-to-pay threshold of €20,000/QALY. Rivaroxaban appeared to be dominant in all scenarios as well, except for the NVAF-patients-only scenario where the incremental cost-effectiveness ratio (ICER) was €157/QALY.

Conclusions: In patients with NVAF or VTE, rivaroxaban treatment is likely to be cost-effective and a potentially cost-saving alternative to VKA in the Netherlands.     

Assessment of the impact of human capital on economic growth

This paper presents updated figures on the dynamics of human capital in the Russian economy. Time series of human capital are obtained for major types of economic activity that cover up to 85–90% of the total human capital in the Russian economy for 1992–2012. An analysis of the impact of accumulated human capital on economic dynamics is performed by means of the production function model. An original approach to assessing the production function based on the method of principal components is introduced.     

On Measurement of Economic Growth

This article continues the discussion raised in the pages of the journal on the methodological problems of justifying economic policy [1]. Problems of measuring the inflationary component of economic growth and in product competitiveness in the internal market and external markets are considered. A procedure to measure economic growth, taking into account the balance of interests of the current and future generations, is proposed.     

Who Has the Time? Community College Students’ Time-Use Response to Financial Incentives

We evaluate the effect of performance-based scholarship programs for post-secondary students on student time use and effort and whether these effects are different for students we hypothesize may be more or less responsive to incentives. To do so, we administered a time-use survey as part of a randomized experiment in which community college students in New York City were randomly assigned to be eligible for a performance-based scholarship or to a control group that was only eligible for the standard financial aid. This paper contributes to the literature by attempting to get inside the “black box” of how students respond to a monetary incentive to improve their educational attainment. We find that students eligible for a scholarship devoted more time to educational activities, increased the quality of effort toward and engagement with their studies, and allocated less time to leisure. Additional analyses suggest that students who were plausibly more myopic (place less weight on future benefits) were more responsive to the incentives, but we find no evidence that students who are arguably more time constrained were less responsive to the incentives.