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461.
In the valuation of the effect of improved air quality through the estimation of hedonic models of house prices, the potential “errors in variables” aspect of the interpolated air pollution measures is often ignored. In this paper, we assess the extent to which this may affect the resulting empirical estimates for marginal willingness to pay (MWTP), using an extensive sample of over 100,000 individual house sales for 1999 in the South Coast Air Quality Management District of Southern California. We take an explicit spatial econometric perspective and account for spatial dependence and endogeneity using recently developed Spatial 2SLS estimation methods. We also account for both spatial autocorrelation and heteroskedasticity in the error terms, using the Kelejian–Prucha HAC estimator. Our results are consistent across different spatial weights matrices and different kernel functions and suggest that the bias from ignoring the endogeneity in interpolated values may be substantial. This paper is part of a joint research effort with James Murdoch (University of Texas, Dallas) and Mark Thayer (San Diego State University). Their valuable input is gratefully acknowledged. The research was supported in part by NSF Grant BCS-9978058 to the Center for Spatially Integrated Social Science (CSISS), and by NSF/EPA Grant SES-0084213. Earlier versions were presented at the 5th International Workshop on Spatial Econometrics and Statistics, Rome, Italy, May 2006, the 53th North American Meetings of the Regional Science Association International, Toronto, ON, Nov. 2006, the 2007 Meetings of the Allied Social Science Assocations, Chicago, IL, Jan 2007, and at departmental seminars at the University of Illinois. Comments by discussants and participants are greatly appreciated. A special thanks to Harry Kelejian for his detailed and patient clarification of the HAC estimator. The usual disclaimer holds.  相似文献   
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This study focuses on job burnout, job engagement, and their relationships with the Big Five personality dimensions: extraversion, agreeableness, conscientiousness, neuroticism, and openness to experience. The data were collected from employees (managerial/supervisory positions and non-supervisory positions) working for quick-service restaurants. Engagement, the emerging new concept, is perceived to be situated at the opposite end of the continuum of burnout, but the results of this study indicate they may be, rather, two distinctive concepts driven by different personality dimensions. The most critical personality trait affecting burnout is neuroticism and the most eminent traits predicting engagement are conscientiousness and neuroticism. This study does not validate the effects of positive personality traits such as extraversion and agreeableness on burnout and they are found to be weakly related to employees’ work engagement, as well.  相似文献   
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The purpose of this study was to examine the internal strategic factors likely to influence company financial performance for service organizations from managers’ perspectives. It provides empirical evidence of the links between the internal strategic factors examined and financial performance of service organizations. Data for this study were collected from middle and upper managers of service companies using a self-administered survey questionnaire. The results of the study suggested that four of the seven critical internal strategic success factors examined had a significant impact on company financial performance. Those factors are sales, R&D and distribution, information technology, and human resources. Implications of the findings are discussed.  相似文献   
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In Canada, parents can give blood exclusively for their child’s transfusion, a process known as directed donation. This qualitative study aimed to understand parents’ perceptions in seeking to provide blood for their newborn. Ten parents whose preterm children were cared for in the Neonatal Intensive Care Unit of one Canadian hospital were interviewed. The beliefs and experiences of parents with regard to directed donation were analyzed with reference to their understanding of the risks and benefits of this form of transfusion. Interview data revealed that parents had little knowledge or understanding of the medical benefits and risks of directed donation and based their decision to seek this type of transfusion largely on emotional grounds. In addition, despite their preference for directed donation, most infants whose parents were interviewed in this study, for practical reasons could not be given this type of transfusion. This may have magnified risk perceptions of non‐directed transfusions. Parents need to be better informed about the medical risks and benefits of directed donation and the actual likelihood that their child will be able to receive this type of transfusion.  相似文献   
467.
Gendered values, norms and preferences shape the intrinsic motivation to provide care for others. This article situates an analysis of this motivation within the broader literature on gender inequality, explaining why it has costly consequences for women in both the home and the labour market, even as it provides considerable personal satisfaction and social benefit. Further movement towards gender equality may depend on the success of political and cultural efforts to ‘de‐gender’ normative obligations to care.  相似文献   
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The purpose of this study was to explore the motivations and contexts that prompt consumers' impulse self-gifting behaviors (ISGB). A thematic analysis of interview data collected from 20 consumers revealed that motivations for ISGB were prompted by specific contexts and that attempts to avoid ISGB through self-control were typical among the participants. Mood states and marketing promotions also emerged as contexts prompting ISGB. Findings were viewed through the conceptual lens of stimulus-organism-response to frame the experience of ISGB as a process. This study expands the literature by considering the implications of impulse purchasing for self-gifting and offering strategic insights for practitioners.  相似文献   
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Abstract

Aims: Protocol T (NCT01627249) was a head-to-head study conducted by the Diabetic Retinopathy Clinical Research Network that compared intravitreal aflibercept, bevacizumab, and ranibizumab for the treatment of diabetic macular edema (DME). A cost-effectiveness analysis accompanying the 1-year data of Protocol T revealed that aflibercept was not cost-effective vs ranibizumab for all patients, but could have been cost-effective in certain patient sub-groups if the 1-year results were extrapolated out to 10?years. The present study evaluated the cost-effectiveness of US Food and Drug Administration-approved anti-vascular endothelial growth factor agents (ranibizumab, aflibercept) for treatment of DME using the 2-year data from Protocol T.

Methods: Costs of aflibercept 2.0?mg or ranibizumab 0.3?mg, visual acuity (VA)-related medical costs, and quality-adjusted life-years (QALYs) were simulated for eight VA health states. Treatment, adverse event management, and VA-related healthcare resource costs (2016 US dollars) were based on Medicare reimbursement and published literature. VA-related health utilities were determined using a published algorithm. Patients were stratified by baseline VA: 20/40 or better; 20/50 or worse.

Results: Total 2-year costs were higher, and QALYs similar, for aflibercept vs ranibizumab in the full cohort ($44,423 vs $34,529; 1.476 vs 1.466), 20/40 or better VA sub-group ($40,854 vs $31,897; 1.517 vs 1.519), and 20/50 or worse VA sub-group ($48,214 vs $37,246; 1.433 vs 1.412), respectively. Incremental cost-effectiveness ratios in the full cohort and 20/50 or worse VA sub-group were $986,159/QALY and $523,377/QALY, respectively. These decreased to $711,301 and $246,978 when analyses were extrapolated to 10?years.

Limitations: Key potential limitations include the fact that VA was the only QALY parameter analyzed and the uncertainty surrounding the role of better- and worse-seeing eye VA in overall functional impairment.

Conclusions: This analysis suggests that aflibercept is not cost-effective vs ranibizumab for patients with DME, regardless of baseline vision.  相似文献   
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