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961.
ABSTRACT

Using synthetic data from the 2008 China Time Use Survey (CTUS) and the 2008 China Household Income Project (CHIP), this study estimates time-poverty rates and compares the profiles of time-poor men and women workers in urban China. In line with previous research, time poverty is defined as a lack of enough time for rest and leisure. Three time-poverty measures are adopted. By all three measures, women paid workers and low-paid workers account for a disproportionate share of the time poor. Regression analysis further shows that, other things being equal, workers who are women, low-paid, married, and who live with children or the elderly in counties with higher overtime rates and lower minimum wage standards are more likely to be time poor. Simulations indicate that enforcing working time regulations and raising minimum wage standards could be effective for reducing time poverty.  相似文献   
962.
Background: Inhibitor development to factor VIII (FVIII) hemophilia therapy results in increased complications and substantial economic costs. The SIPPET study, the first randomized controlled trial to compare the immunogenicity of plasma-derived FVIII (pdFVIII)/von Willebrand factor (VWF) and recombinant-DNA-derived FVIII (rFVIII), demonstrated higher inhibitor rates in previously untreated patients (PUPs) treated with rFVIII than in PUPs treated with pdFVIII/VWF.

Objective: To quantify the economic impact of treating PUPs with pdFVIII/VWF vs rFVIII.

Methods: An Excel-based clinical and economic model was developed from a US healthcare payer perspective and run over a 5-year period. The analysis utilized a cohort approach to model patient treatment and outcomes over a monthly cycle to quantify differences in costs of FVIII, bypassing agents, and hospitalizations for serious bleeds. Rates of high-titer inhibitor development were obtained from the SIPPET study. Patients developing high-titer inhibitors were treated with immune tolerance induction (ITI). Patients who developed low-titer inhibitors and those who did not develop inhibitors continued their usual FVIII treatment. Patients who were successfully treated with ITI returned to FVIII treatment, while unsuccessfully treated patients received bypassing agents. Total costs per treated patient were estimated and a one-way sensitivity analysis was conducted to quantify the impact of parameter uncertainty on the model outcomes.

Results: Total cumulative costs per patient over 5 years were $834,621 for pdFVIII/VWF patients and $1,237,163 for rFVIII patients, representing a total saving of $402,542 per patient over the 5-year period, for an average annual saving of $80,508 per patient.

Conclusions: Based on data from the SIPPET study, this analysis found that initiating FVIII treatment in severe hemophilia A PUPs with pdFVIII/VWF has the potential to offer substantial cost savings to healthcare payers, amounting to a one-third reduction in costs.  相似文献   
963.
Background: There is a critical need to focus limited resources on sub-groups of patients with obesity where we expect the largest return on investment. This paper identifies patient sub-groups where an investment may result in larger positive economic and health outcomes.

Methods: The baseline population with obesity was derived from a public survey database and divided into sub-populations defined by demographics and disease status. In 2016, a validated model was used to simulate the incidence of diabetes, absenteeism, and direct medical cost in five care settings. Research findings were derived from the difference in population outcomes with and without weight loss over 15 years. Modeled weight loss scenarios included initial 5% or 12% reduction in body mass index followed by a gradual weight regain. Additional simulations were conducted to show alternative outcomes from different time courses and maintenance scenarios.

Results: Univariate analyses showed that age 45–64, pre-diabetes, female, or obesity class III are independently predictive of larger savings. After considering the correlation between these factors, multivariate analyses projected young females with obesity class I as the optimal sub-group to control obesity-related medical expenditures. In contrast, the population aged 20–35 with obesity class III will yield the best health outcomes. Also, the sub-group aged 45–54 with obesity class I will produce the biggest productivity improvement. Each additional year of weight loss maintained showed increased financial benefits.

Conclusions: This paper studied the heterogeneity between many sub-populations affected by obesity and recommended different priorities for decision-makers in economic, productivity, and health realms.  相似文献   
964.
965.
966.
This article investigates the dynamic relationships among sectoral economic activities, macro expenditure patterns, renewable and non-renewable energy consumption and unemployment in 41 countries from 1980 to 2014. The state of the art econometric techniques, both linear and non-linear panel and time series estimation techniques are used. The results show that industrialization, services sector, government expenditure and trade openness play a positive role in reducing unemployment, while agriculture and renewable energy consumption increase unemployment. This might be, in part, due to recent technological advancements and large capital intensive investments in agriculture and renewable energy sectors. Therefore, dedicated social and labour market policies need to be adopted to complement greening economic policies.  相似文献   
967.
This paper studies the relation between inflation and economic development. The literature is largely silent regarding both the theoretical and empirical perspectives that undeveloped countries endure higher average inflation than developed economies. We present a simple theoretical model linking the inflation phenomenon to the tradition of development economics. Empirical evidence is garnered to test the hypothesis that economic development engenders a downward bias to inflation rates. Through the feasible-GLS estimator in a panel of 65 countries from 2001 to 2011, we aim at listing a number of variables most commonly used to explain differences in the stage of economic development across countries and identifying the most statistically relevant ones to account for differences in inflationary patterns. While our results show that inflation is inversely correlated with the level of the technological content of the economy (measured by share of high-tech exports), human capital and cyclical unemployment, it is directly related to the degree of inflation persistence and terms of trade growth. However, our findings still present an inverse and low correlation between inflation persistence and economic development, implying that development-sensitive variables allowed into the model can only partially account for the differences in inflation at different levels of economic development.  相似文献   
968.
Research analysing the antecedents of a firm’s absorptive capacity suggests that transformational leadership (TL) is one of its main determinants. However, the few studies focusing on the relationship between these two variables do not explicitly assess why transformational leaders facilitate knowledge acquisition, sharing and retention inside firms. This paper suggests that the reason is that the former contributes to the creation of an organisational context that favours learning processes. We test our research model on a sample of 467 Spanish industrial firms. Findings provide evidence that TL is positively related to the firm’s absorptive capacity and that this relationship is mediated by some organisational learning facilitators: experimentation, risk-taking, interacting with external environment and dialogue.  相似文献   
969.
Adoption of a new ICT tool in the fisheries sector depends on several factors such as ease of use, affordable cost, information, and time. All these factors determine the preference of an existing tool over others for productivity enhancement. Which ICT tool is more beneficial than others is a continuing debate among researchers. However, the literature currently lacks detailed studies of fishermen criteria for selecting the best ICT tools in the marine fisheries sector. This paper is based on a framework which explains the factors influencing the adoption of ICT tools for the better fish catch, with the help of a multi-criteria decision making approach, called Analytic Hierarchy Process. Also, in the study we have compared the results of analysis using AHP with popular method TOPSIS and the obtained results were validated. The Study also assesses scientifically, which is the most important ICT tool for fishing through a case study in Northern and Southern parts of Kerala, a state in the southern India. The Study finds that Global Positioning System (GPS) is the most beneficial and important ICT tool in marine fishing. In contrast to the earlier studies, the results show that wireless set is important than other tools like mobile phone and echo-sounder for multi-day fishing. The cost-benefit analysis also supports findings of the study.  相似文献   
970.
This article compares the salary structure of tenured and tenure-track faculty across schools within the university systems of North Carolina and New York. Specifically, we establish a positive relationship between school prestige and salary inequality, both overall and within specific academic ranks. This result suggests that the value to teaching is less discipline-specific than the value to research output. Marked differences in the aforementioned statistical linkage across academic ranks also confirm prior speculation that junior faculty salaries are more closely tied to academic value than senior faculty salaries.  相似文献   
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